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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:23 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 408 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scars Clear all
Active, not recruiting Not applicable Interventional

CO2 Laser Revision for Burn Related Donor Site Scars

NCT04456127
View directory record Official record
Conditions
Burn Scar, Scar, Skin Graft Scar
Interventions
Fractional CO2 Laser
Procedure
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 31, 2025 · Synced Oct 21, 2026, 7:23 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Prospective Observation of Wound Healing With Prevena Incision Management System

NCT01704924
View directory record Official record
Conditions
Scarring
Interventions
Prevena, Standard of Care Dressing
Device · Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 19, 2018 · Synced Oct 21, 2026, 7:23 AM EDT
Not yet recruiting Phase 2 Interventional

The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial

NCT07583862
View directory record Official record
Conditions
Surgical Wounds, Mohs Surgery
Interventions
Topical Timolol, Normal Saline
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement

NCT05358860
View directory record Official record
Conditions
Acne Scars - Mixed Atrophic and Hypertrophic
Interventions
Sofwave
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
22 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
4
States / cities
Hackensack, New Jersey • New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 21, 2026, 7:23 AM EDT
Terminated Phase 2 Interventional Results available

Imiquimod for Preventing Keloid Recurrence

NCT03760250
View directory record Official record
Conditions
Keloid
Interventions
Imiquimod 5% cream
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty

NCT01037985
View directory record Official record
Conditions
Scar Prevention
Interventions
EXC 001, Placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 45 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
6
States / cities
La Jolla, California • Chicago, Illinois • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2021 · Synced Oct 21, 2026, 7:23 AM EDT
Terminated Phase 1 Interventional

Evaluating Autologous Stromal Vascular Fraction in Subjects with Vocal Fold Scar

NCT05354544
View directory record Official record
Conditions
Vocal Fold Scars
Interventions
Autologous adipose derived SVF
Biological
Lead sponsor
Shane A. Shapiro
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 21, 2026, 7:23 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Poly-4-Hydroxybutyrate Scaffold in Rhytidectomy

NCT07132892
View directory record Official record
Conditions
Tissue Adhesion
Interventions
Galaflex Lite Scaffold
Device
Lead sponsor
Jeffrey M. Kenkel
Other
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Not yet recruiting Not applicable Interventional

Tools for Return of Facial Function

NCT07825844
View directory record Official record
Conditions
Facial Scarring, Facial Trauma, Burn, Orofacial Contracture, Facial Scar Contracture
Interventions
Intraoral Stretching Splints
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
7 Years to 100 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Recruiting Phase 3 Interventional

Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

NCT05677971
View directory record Official record
Conditions
Alpha1-Antitrypsin Deficiency
Interventions
Fazirsiran Injection, Placebo
Drug · Other
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
37
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Completed No phase listed Observational

Hypertrophic Scarring After Facial Burn

NCT00242970
View directory record Official record
Conditions
Burn
Interventions
3-Dimensional Color Scanning
Device
Lead sponsor
Legacy Health System
Other
Eligibility
4 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2015 · Synced Oct 21, 2026, 7:23 AM EDT
Recruiting Phase 3 Interventional

Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

NCT06165341
View directory record Official record
Conditions
Alpha1-Antitrypsin Deficiency
Interventions
Fazirsiran Injection, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
20
States / cities
Phoenix, Arizona • Tucson, Arizona • La Jolla, California + 15 more
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of the Composition of Dental Plaque

NCT00001726
View directory record Official record
Conditions
Dental Caries, Dental Plaque, Periodontal Disease
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional Results available

An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures

NCT05981443
View directory record Official record
Conditions
Brow Ptosis, Surgical Wound
Interventions
Dermabond, Non-Absorbable Sutures
Device · Other
Lead sponsor
Cody Blanchard
Other
Eligibility
18 Years to 100 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 24, 2025 · Synced Oct 21, 2026, 7:23 AM EDT
Active, not recruiting Not applicable Interventional

Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects

NCT05074238
View directory record Official record
Conditions
Surgical Wound, Wound Heal, Wound of Skin, Scar
Interventions
Zinc containing suncreen
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Seprafilm® Adhesion Barrier and Cesarean Delivery

NCT00565643
View directory record Official record
Conditions
Adhesions, Cesarean Section, Delivery, Obstetric
Interventions
modified sodium hyaluronic acid and carboxymethylcellulose, Placebo
Device
Lead sponsor
Winthrop University Hospital
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
753 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2014
U.S. locations
3
States / cities
Mineola, New York • Stony Brook, New York • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 14, 2024 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures

NCT03891004
View directory record Official record
Conditions
Surgical Wound, Tissue Adhesion
Interventions
Subcuticular Skin Closure, Tissue Adhesives
Procedure · Device
Lead sponsor
St. John Hospital & Medical Center
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2019 · Synced Oct 21, 2026, 7:23 AM EDT
Terminated Not applicable Interventional Results available

Ablative Fractional Laser for Sclerotic GVHD-Associated Joint Contractures

NCT02881047
View directory record Official record
Conditions
Subjects With Severe, Refractory Sclerotic Skin Changes
Interventions
CO2 Laser, Ultrasound, Skin Biopsy
Device · Radiation · Diagnostic Test
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional

Treatment of Surgical Scars With Fractional Photothemolysis Versus Pulse Dye Laser

NCT00685243
View directory record Official record
Conditions
Post Surgical Scars
Interventions
Laser treatment
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
West Bloomfield, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Pressure Garment Therapy After Burns

NCT01005732
View directory record Official record
Conditions
Hypertrophic Scarring After Burn Injury
Interventions
Custom fabricated pressure garments
Device
Lead sponsor
University of Washington
Other
Eligibility
7 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1995 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 4, 2011 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Reducing Side-effects of Autologous Skin Tissue Harvesting

NCT02234193
View directory record Official record
Conditions
Scar
Interventions
Micro biopsy, Lidocaine with epinephrine
Device · Procedure
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dermabrasion in Mohs: Split-Scar Trial

NCT07213921
View directory record Official record
Conditions
Wound Heal
Interventions
Dermabrasion
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Recruiting Phase 1 Interventional

Topical CBD Scar Healing Study

NCT06129591
View directory record Official record
Conditions
Paramedian Forehead Flap
Interventions
Vantage Hemp CBD Isolate + Silicone patch, Silicone patch
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 21, 2026, 7:23 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Open-label, Prospective, Multicenter Study to Evaluate the Cutera Excel V™ Laser and a Micro-Lens Array Attachment

NCT03424148
View directory record Official record
Conditions
Scarring, Skin Aging
Interventions
Excel V™ Laser & Micro-Lens Array Attach
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Brisbane, California • Sacramento, California
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Oct 21, 2026, 7:23 AM EDT