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ClinicalTrials.gov public records Last synced Oct 30, 2026, 12:37 AM EDT

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Showing 1–24 of 190 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scoliosis Clear all
Completed Phase 4 Interventional

Perioperative Steroid Dosing on the APR in AIS

NCT05561725
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
Dexamethasone postoperative, Standard of Care
Drug
Lead sponsor
Emory University
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Completed Phase 4 Interventional

IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction

NCT05730920
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
Interventions
Methadone, Liposomal bupivacaine (LB, Exparel)
Drug
Lead sponsor
Dr. Casey Stondell, MD
Other
Eligibility
11 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 30, 2026, 12:37 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Postural Study Comparing Sitting on the Floor Versus Sitting in a Chair While Playing Video Games.

NCT01163955
View directory record Official record
Conditions
Scoliosis
Interventions
Time to fatigue
Other
Lead sponsor
Glinn and Giordano Physical Therapy
Other
Eligibility
5 Years to 15 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Nov 2, 2011 · Synced Oct 30, 2026, 12:37 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Smart Textile Technology for Scoliosis

NCT02080611
View directory record Official record
Conditions
Spinal Deformities, Scoliosis, Kyphosis
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 30, 2017 · Synced Oct 30, 2026, 12:37 AM EDT
Not listed Not applicable Interventional

Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury

NCT00256672
View directory record Official record
Conditions
Scoliosis
Interventions
Thoraco-Lumbar-Sacral-Orthoses (TLSO) / Flex-Foam
Device
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
5 Years to 16 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
3
States / cities
Sacramento, California • Chicago, Illinois • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 13, 2008 · Synced Oct 30, 2026, 12:37 AM EDT
Terminated Phase 4 Interventional Results available

A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

NCT05552443
View directory record Official record
Conditions
Pain Control
Interventions
Hydromorphone 2.5 mcg/kg, Hydromorphone 2.75 mcg/kg, Hydromorphone 3 mcg/kg, Hydromorphone 3.25 mcg/kg, Hydromorphone 3.5 mcg/kg, Hydromorphone 4 mcg/kg, Hydromorphone 4.5 mcg/kg, Hydromorphone 5 mcg/kg, Hydromorphone 5.5 mcg/kg, Hydromorphone 6 mcg/kg, Hydromorphone 6.5 mcg/kg, Hydromorphone 7 mcg/kg
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
10 Years to 17 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Active, not recruiting No phase listed Observational

Postoperative and Chronic Pain Genetic Spine and Pectus Surgery Study

NCT02998138
View directory record Official record
Conditions
Scoliosis, Kyphosis, Kyphoscoliosis, Pectus Excavatum
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years and older
Enrollment
880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
5
States / cities
Stanford, California • Baltimore, Maryland • Jackson, Mississippi + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Terminated Phase 4 Interventional Results available

IV Lidocaine in Pediatric AIS

NCT03893318
View directory record Official record
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
IV lidocaine, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 30, 2026, 12:37 AM EDT
Terminated Phase 4 Interventional

Comparison of Actifuse ABX and Local Bone in Spinal Surgery

NCT01852747
View directory record Official record
Conditions
Scoliosis, Kyphosis, Lordosis
Interventions
Multilevel Spinal fusion with Actifuse ABX®
Procedure
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 80 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 28, 2017 · Synced Oct 30, 2026, 12:37 AM EDT
Withdrawn No phase listed Observational

ADDRESS - Adult Deformity Robotic vs. Freehand Surgery to Correct Spinal Deformity

NCT02058238
View directory record Official record
Conditions
Scoliosis, Kyphosis, Kyphoscoliosis, Spinal Deformity, Spondylosis
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 30, 2026, 12:37 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

NCT03059420
View directory record Official record
Conditions
Congenital Fibrosis of Extraocular Muscles, Duane Retraction Syndrome, Duane Radial Ray Syndrome, Mobius Syndrome, Brown Syndrome, Marcus Gunn Syndrome, Strabismus Congenital, Horizontal Gaze Palsy, Horizontal Gaze Palsy With Progressive Scoliosis, Facial Palsy, Facial Paresis, Hereditary, Congenital, Third Nerve Palsy, Fourth Nerve Palsy, Sixth Nerve Palsy, Synkinesis, Ocular Motility Disorders, Levator-Medial Rectus Synkinesis, Athabaskan Brainstem Dysgenesis, Tongue Paralysis, Ninth Nerve Disorder, Fifth Nerve Palsy, Seventh Nerve Palsy, Eleventh Nerve Disorder, Twelfth Nerve Disorder, Vagus Nerve Paralysis, Moebius Sequence
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Day and older
Enrollment
20,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Incobotulinumtoxin A and Yoga-like Isometric Exercise in Adolescent Idiopathic Lumbar Scoliosis

NCT04922983
View directory record Official record
Conditions
Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis; Lumbar Region
Interventions
Botulinum toxin type A, Isometric Yoga-like exercise, Placebo
Drug · Behavioral
Lead sponsor
Manhattan Physical Medicine and Rehabilitation, LLP
Other
Eligibility
14 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Manhattan, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2023 · Synced Oct 30, 2026, 12:37 AM EDT
Completed No phase listed Observational

Scoliosis Surgery Using the PASS® LP System

NCT01019109
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Posterior Spinal Fusion Device: Titanium rod arm used titanium rods, and CoCr rod arm used Cobalt Chrome rods as a part of the construct.
Device
Lead sponsor
Medicrea, USA Corp.
Industry
Eligibility
Not listed
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
3
States / cities
Atlanta, Georgia • New Orleans, Louisiana • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 21, 2018 · Synced Oct 30, 2026, 12:37 AM EDT
Recruiting Not applicable Interventional

Open-label Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

NCT06365892
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS)
Interventions
open-label placebo, Treatment as usual
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Enrolling by invitation Not applicable Interventional

Anterior Vertebral Body Tethering (AVBT) Using Zimmer Biomet Tether System or Dynesys System Components to Treat Pediatric Scoliosis

NCT03506334
View directory record Official record
Conditions
Scoliosis
Interventions
AVBT using Dynesys System Components, Spine fusion
Device · Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
10 Years to 16 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Active, not recruiting Not applicable Interventional

Casting vs Bracing for Idiopathic Early-Onset Scoliosis

NCT04500041
View directory record Official record
Conditions
Scoliosis Idiopathic, Early-Onset Scoliosis Deformity of Spine
Interventions
Casting, Bracing
Procedure · Device
Lead sponsor
University of Iowa
Other
Eligibility
12 Months to 36 Months
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
24
States / cities
Little Rock, Arkansas • Aurora, Colorado • Wilmington, Delaware + 18 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Terminated Not applicable Interventional Results available

Single vs Double Epidural Catheter Analgesia for Scoliosis Surgery

NCT01900626
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
epidural catheter
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
11 Years to 18 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 8, 2019 · Synced Oct 30, 2026, 12:37 AM EDT
Completed Phase 4 Interventional Results available

Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion

NCT00880607
View directory record Official record
Conditions
Pain Management, Spinal Fusion, Scoliosis
Interventions
Intrathecal morphine, Extended Release Epidural Morphine
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 17 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 22, 2020 · Synced Oct 30, 2026, 12:37 AM EDT
Recruiting No phase listed Observational

Personalized Spine Study Group (PSSG) Registry

NCT04601363
View directory record Official record
Conditions
Scoliosis; Adolescence, Degenerative Disc Disease, Spinal Fusion, Kyphoscoliosis, Pseudoarthrosis of Spine, Spinal Stenosis, Kyphoses, Scheuermann
Interventions
Patient Specific Rod
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 85 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Oct 30, 2026, 12:37 AM EDT
Completed Phase 2Phase 3 Interventional Results available

An Open-label Trial of Clevidipine for Controlled Hypotension During Spinal Fusion

NCT01645111
View directory record Official record
Conditions
Neuromuscular Scoliosis
Interventions
Clevidipine
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 18, 2015 · Synced Oct 30, 2026, 12:37 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Kids With Iron Deficiency and Scoliosis

NCT06042699
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies, Anemia, Spinal Fusion, Postoperative Cognitive Dysfunction
Interventions
Oral ferrous sulfate, Oral placebo tablet
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 26 Years
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery?

NCT01813058
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 30, 2026, 12:37 AM EDT
Recruiting Not applicable Interventional

REFLECT Scoliosis System Post Approval Study

NCT06298812
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
REFLECT Scoliosis Correction System
Device
Lead sponsor
Globus Medical Inc
Industry
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2032
U.S. locations
2
States / cities
Rochester, Minnesota • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 30, 2026, 12:37 AM EDT
Completed Not applicable Interventional Results available

Vertebral Body Tethering Outcomes for Pediatric Idiopathic Scoliosis

NCT03194568
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Anterior Vertebral Tether
Device
Lead sponsor
Patrick Cahill, MD
Other
Eligibility
8 Years to 16 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 23, 2024 · Synced Oct 30, 2026, 12:37 AM EDT