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ClinicalTrials.gov public records Last synced Sep 14, 2026, 2:42 AM EDT

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Showing 1–24 of 187 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Scoliosis Clear all
Recruiting Not applicable Interventional

Studying Melatonin and Recovery in Teens

NCT06093477
View directory record Official record
Conditions
Juvenile; Scoliosis, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis;Congenital, Kyphosis, Spondylolisthesis, Pectus Surgery, Hip Surgery
Interventions
Fast-Dissolve Melatonin Pill, Fast-Dissolve Placebo Pill
Dietary Supplement · Other
Lead sponsor
Stanford University
Other
Eligibility
12 Years to 18 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 14, 2026, 2:42 AM EDT
Terminated Phase 4 Interventional Results available

Posterior Spinal Fusion With Two Energy Dissection Techniques

NCT02465099
View directory record Official record
Conditions
Scoliosis
Interventions
Ultrasonic Dissection (UD), Electrocautery Dissection (ED)
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
10 Years to 21 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
5
States / cities
Madera, California • Wilmington, Delaware • Chicago, Illinois + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2018 · Synced Sep 14, 2026, 2:42 AM EDT
Completed No phase listed Observational

Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

NCT03539770
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent
Interventions
Posterior spinal fusion
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
8 Years to 21 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2018 · Synced Sep 14, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Erector Spinae Plane Blockade in Pediatric Scoliosis Surgery Patients

NCT04153994
View directory record Official record
Conditions
Scoliosis; Juvenile, Scoliosis; Adolescence
Interventions
Erector Spinae Plane Blockade
Procedure
Lead sponsor
Stanford University
Other
Eligibility
Up to 18 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Sep 14, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional

Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

NCT07167927
View directory record Official record
Conditions
Children With Medical Complexity (CMC), Multiple Chronic Conditions, Neuromuscular Scoliosis, Shared Decision Making, Decision Support Systems, Clinical, Decision Aids
Interventions
Decision support tool
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
8 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 14, 2026, 2:42 AM EDT
Completed Phase 2 Interventional Results available

Methadone vs Magnesium in Spinal Fusion

NCT01795495
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Methadone hydrochloride, Magnesium Sulfate, Remifentanil
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 19 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2018 · Synced Sep 14, 2026, 2:42 AM EDT
Completed Phase 4 Interventional

IV Methadone Vs EXPAREL Erector Spinae Plane Blockade in Pediatric Subjects Undergoing Idiopathic Scoliosis Correction

NCT05730920
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Juvenile Idiopathic Scoliosis
Interventions
Methadone, Liposomal bupivacaine (LB, Exparel)
Drug
Lead sponsor
Dr. Casey Stondell, MD
Other
Eligibility
11 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Sep 14, 2026, 2:42 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Kids With Iron Deficiency and Scoliosis

NCT06042699
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Neuromuscular Scoliosis, Perioperative/Postoperative Complications, Iron Deficiencies, Anemia, Spinal Fusion, Postoperative Cognitive Dysfunction
Interventions
Oral ferrous sulfate, Oral placebo tablet
Dietary Supplement
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 26 Years
Enrollment
275 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Sep 14, 2026, 2:42 AM EDT
Completed No phase listed Observational

A Prospective Study of Instrumented, Posterolateral Lumbar Fusions (PLF) With OsteoAMP®

NCT02225444
View directory record Official record
Conditions
Spondylolisthesis, Scoliosis, Intervertebral Disc Disease
Interventions
OsteoAMP
Other
Lead sponsor
Bioventus LLC
Industry
Eligibility
21 Years to 85 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
9
States / cities
New Haven, Connecticut • Chicago, Illinois • Kansas City, Kansas + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2020 · Synced Sep 14, 2026, 2:42 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

3-D Correction of Adolescent Idiopathic Scoliosis (AIS) With Differential Metals

NCT05631821
View directory record Official record
Conditions
Juvenile and Adolescent Idiopathic Scoliosis
Interventions
differential rod bending with rod contours (MESA Spinal System)
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
10 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 1, 2022 · Synced Sep 14, 2026, 2:42 AM EDT
Recruiting No phase listed Observational

Clinical Orthopaedic Data Bank (Acute and Chronic)

NCT00411060
View directory record Official record
Conditions
Osteoarthritis, Osteosarcoma, Scoliosis, Cerebral Palsy
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
Not listed
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 14, 2026, 2:42 AM EDT
Completed Not applicable Interventional

SIMDiscovery: The Benefits of Utilizing a Simulation Preparation Program for Spinal Fusion Surgery

NCT03835390
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent
Interventions
SIMDiscovery
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 6, 2020 · Synced Sep 14, 2026, 2:42 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Hypertonic Saline in Posterior Spinal Fusion

NCT06822374
View directory record Official record
Conditions
Scoliosis Idiopathic, Scoliosis;Congenital
Interventions
Normosol-R, buffered 2% hypertonic saline
Drug
Lead sponsor
Joseph D. Tobias
Other
Eligibility
10 Years to 25 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 9, 2025 · Synced Sep 14, 2026, 2:42 AM EDT
Terminated Not applicable Interventional Results available

Safety Outcomes of Vertebral Body Tethering Technique

NCT04119284
View directory record Official record
Conditions
Idiopathic Adolescent Scoliosis
Interventions
Anterior body tether (ABT)
Device
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
8 Years to 16 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 12, 2025 · Synced Sep 14, 2026, 2:42 AM EDT
Not yet recruiting Phase 4 Interventional

Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients

NCT06023043
View directory record Official record
Conditions
Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Dexamethasone
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
9 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 14, 2026, 2:42 AM EDT
Not listed Not applicable Interventional

The Effect Spinal Bracing System on Gait in Adult Scoliosis Patients

NCT03572855
View directory record Official record
Conditions
Scoliosis
Interventions
Scoliosis Brace
Combination Product
Lead sponsor
Texas Back Institute
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Plano, Texas
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 14, 2026, 2:42 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Study of 3D Scanning for Adolescent Scoliosis

NCT06035952
View directory record Official record
Conditions
Scoliosis
Interventions
3D topographical scan
Diagnostic Test
Lead sponsor
NSite Medical
Industry
Eligibility
10 Years to 18 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
2
States / cities
Palo Alto, California • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Sep 14, 2026, 2:42 AM EDT
Not listed No phase listed Observational

Prospective Database Registry Study of Scoliosis in Children With Cerebral Palsy

NCT00680264
View directory record Official record
Conditions
Cerebral Palsy, Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
8 Years to 21 Years
Enrollment
402 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2025
U.S. locations
12
States / cities
San Diego, California • Wilmington, Delaware • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 14, 2026, 2:42 AM EDT
Enrolling by invitation No phase listed Observational

Changes in Cerebral Oxygenation Related to Intraoperative Position Changes

NCT06910228
View directory record Official record
Conditions
Scoliosis Patients
Interventions
Near infrared spectroscopy (NIRS)
Device
Lead sponsor
Joseph D. Tobias
Other
Eligibility
10 Years to 21 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 26, 2025 · Synced Sep 14, 2026, 2:42 AM EDT
Not listed No phase listed Observational

Adolescent Idiopathic Scoliosis Outcomes Database Registry

NCT01661959
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
10 Years to 21 Years
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2025
U.S. locations
12
States / cities
San Diego, California • Wilmington, Delaware • Miami, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 14, 2026, 2:42 AM EDT
Completed No phase listed Observational

Development of a Conservative Care and Bracing Registry (CCBR)

NCT07527611
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis, Juvenile Idiopathic Scoliosis, Infantile Idiopathic Scoliosis, Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
National Scoliosis Center
Other
Eligibility
1 Year to 18 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 14, 2026, 2:42 AM EDT
Withdrawn No phase listed Observational

Test-Retest Reliability of Pulmonary Function Tests in Patients With Duchenne's Muscular Dystrophy

NCT00207857
View directory record Official record
Conditions
Duchenne's Muscular Dystrophy, Scoliosis
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
6 Years to 21 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 3, 2015 · Synced Sep 14, 2026, 2:42 AM EDT
Active, not recruiting No phase listed Observational

Postoperative and Chronic Pain Genetic Spine Surgery Study

NCT02998138
View directory record Official record
Conditions
Scoliosis, Kyphosis, Kyphoscoliosis
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 18 Years
Enrollment
880 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
5
States / cities
Stanford, California • Baltimore, Maryland • Jackson, Mississippi + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Sep 14, 2026, 2:42 AM EDT
Completed Not applicable Interventional

Incidence of Proximal Junctional Kyphosis (PJK) in Long Posterior Spinal Fusion: A Study Comparing Traditional Open Surgery to Minimally Invasive Percutaneous Technique at the Proximal Fusion Levels

NCT00890227
View directory record Official record
Conditions
Scoliosis, Kyphosis
Interventions
Traditional technique, Minimally invasive technique
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 14, 2026, 2:42 AM EDT