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ClinicalTrials.gov public records Last synced Oct 9, 2026, 12:53 AM EDT

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Showing 49–72 of 188 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scoliosis, Unspecified Clear all
Recruiting Phase 3 Interventional

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

NCT07561827
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Ropivacaine Hydrocloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 9, 2026, 12:53 AM EDT
Completed Phase 1 Interventional Results available

Susceptibility of Motor-Evoked Potentials to Varying Targeted Blood Levels of Dexmedetomidine

NCT00671931
View directory record Official record
Conditions
Scoliosis
Interventions
low dexmedetomidine, low propofol, high dexmedetomidine, low propofol, Dexmedetomidine, Dexmedetomidin
Drug
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
10 Years to 25 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 23, 2013 · Synced Oct 9, 2026, 12:53 AM EDT
Terminated Not applicable Interventional

Vertebral Body Tethering Treatment for Idiopathic Scoliosis

NCT03802656
View directory record Official record
Conditions
Scoliosis, Spinal Curvatures, Spinal Diseases, Bone Diseases, Musculoskeletal Disease, Adolescent Idiopathic Scoliosis, Juvenile; Scoliosis
Interventions
Anterior Vertebral Body Tethering
Device
Lead sponsor
Ochsner Health System
Other
Eligibility
8 Years to 16 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational

The Treatment of Progressive Early Onset Spinal Deformities: A Multi-Center Outcome Study

NCT02299362
View directory record Official record
Conditions
Early Onset Scoliosis, Congenital Spinal Deformities, Infantile Idiopathic Scoliosis, Neuromuscular Spinal Deformity, Syndromic Spinal Deformity, Thoracic Insufficiency Syndrome
Interventions
Not listed
Lead sponsor
Growing Spine Study Group
Other
Eligibility
1 Day to 18 Years
Enrollment
2,602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2020
U.S. locations
19
States / cities
Little Rock, Arkansas • Los Angeles, California • San Diego, California + 16 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 9, 2026, 12:53 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

A Trial Comparing Single Intra-op Dose of Methadone Versus Placebo in Patients Undergoing Spine Surgery

NCT02206685
View directory record Official record
Conditions
Thoracolumbar Scoliosis
Interventions
Methadone, Normal Saline
Drug
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 17 Years
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2021 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Changes in Cerebral Oxygenation During the Administration of Cell Saver Blood and Allogeneic Blood

NCT02607150
View directory record Official record
Conditions
Idiopathic Scoliosis, Transfusion Reaction
Interventions
Cerebral Oxygenation Changes
Other
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2016 · Synced Oct 9, 2026, 12:53 AM EDT
Not yet recruiting Early Phase 1 Interventional

Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover

NCT07766824
View directory record Official record
Conditions
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients, Lumbar Spondylosis, Lumbar Spondylolisthesis, Cervical Spondylosis and Spondylolisthesis, Post Laminectomy Cervical Syndrome, Cervical Myelopathy
Interventions
Ready Set Recover
Behavioral
Lead sponsor
National University of Natural Medicine
Other
Eligibility
18 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 9, 2026, 12:53 AM EDT
Completed Not applicable Interventional Results available

A Multicenter Prospective Study of Quality of Life in Adult Scoliosis

NCT00854828
View directory record Official record
Conditions
Scoliosis
Interventions
Surgical intervention, Non-operative intervention
Procedure · Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 80 Years
Enrollment
286 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
7
States / cities
Chicago, Illinois • Louisville, Kentucky • Baltimore, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 14, 2021 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational

Development of a Conservative Care and Bracing Registry (CCBR)

NCT07527611
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Ealy Onset Scoliosis, Juvenile Idiopathic Scoliosis, Infantile Idiopathic Scoliosis, Neuromuscular Scoliosis
Interventions
Not listed
Lead sponsor
National Scoliosis Center
Other
Eligibility
1 Year to 18 Years
Enrollment
280 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 9, 2026, 12:53 AM EDT
Recruiting Not applicable Interventional

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

NCT03292601
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
NYRC Brace Scoliosis Monitor
Device
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 17 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 9, 2026, 12:53 AM EDT
Completed Not applicable Interventional

Long-Term Outcome Following the Treatment of Pediatric Scoliosis

NCT01760434
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Long-term outcomes
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 99 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2019 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational

MLX/XLX ACR Expandable Lumbar Interbody Implants

NCT04420143
View directory record Official record
Conditions
Degenerative Disc Disease, Spondylolisthesis, Degenerative Scoliosis
Interventions
Not listed
Lead sponsor
NuVasive
Industry
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
4
States / cities
Orange, California • Jacksonville, Florida • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 22, 2025 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational

Is Pleth Variability Index (PVI) a Surrogate for Pulse Pressure Variations (PPV) in Pediatric Spine Fusion (SF) Surgery?

NCT00994656
View directory record Official record
Conditions
Scoliosis, Spinal Fusion
Interventions
Masimo multi-wavelength pulse co-oximeter
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 11, 2011 · Synced Oct 9, 2026, 12:53 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery

NCT06096181
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil, Dexmedetomidine, Posterior Spinal Fusion
Interventions
Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
Drug
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
12 Years to 18 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 9, 2026, 12:53 AM EDT
Withdrawn No phase listed Observational

Test-Retest Reliability of Pulmonary Function Tests in Patients With Duchenne's Muscular Dystrophy

NCT00207857
View directory record Official record
Conditions
Duchenne's Muscular Dystrophy, Scoliosis
Interventions
Not listed
Lead sponsor
Children's Healthcare of Atlanta
Other
Eligibility
6 Years to 21 Years · Male only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 4, 2015 · Synced Oct 9, 2026, 12:53 AM EDT
Recruiting Not applicable Interventional

Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis

NCT07167927
View directory record Official record
Conditions
Children With Medical Complexity (CMC), Multiple Chronic Conditions, Neuromuscular Scoliosis, Shared Decision Making, Decision Support Systems, Clinical, Decision Aids
Interventions
Decision support tool
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
8 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 9, 2026, 12:53 AM EDT
Not listed Not applicable Interventional

Single Versus Dual Spine Attending Surgeons in Complex Adult Deformity Surgery:

NCT02703831
View directory record Official record
Conditions
Scoliosis, Unspecified
Interventions
Dual attending, Single Attending
Procedure
Lead sponsor
Norton Leatherman Spine Center
Other
Eligibility
25 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 9, 2016 · Synced Oct 9, 2026, 12:53 AM EDT
Terminated Not applicable Interventional

Thromboelastography Transfusion Protocol for Pediatric Neuromuscular Scoliosis Surgery

NCT02670798
View directory record Official record
Conditions
Neuromuscular Scoliosis
Interventions
Thromboelastography laboratory testing
Procedure
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated May 3, 2018 · Synced Oct 9, 2026, 12:53 AM EDT
Recruiting Phase 2Phase 3 Interventional

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

NCT07217873
View directory record Official record
Conditions
Scoliosis Correction, Iron Deficiency, Transfusion Blood, Surgery Complications, Spinal Fusion, Scoliosis Idiopathic Adolescent, Scoliosis Neuromuscular
Interventions
Ferric carboxymaltose IV, Normal Saline (Placebo)
Drug
Lead sponsor
Columbia University
Other
Eligibility
10 Years to 19 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 9, 2026, 12:53 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Effect of Adult Spinal Deformity Surgery on Functional Reach

NCT06258161
View directory record Official record
Conditions
Scoliosis, Scoliosis Kyphosis
Interventions
Spinal Fusion, No intervention
Procedure · Other
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational

Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery

NCT01408823
View directory record Official record
Conditions
Scoliosis
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 9, 2026, 12:53 AM EDT
Completed No phase listed Observational

Validation of Triggered EMG Values for Pedicle Screws Using a Powered Screwdriver

NCT02064101
View directory record Official record
Conditions
Scoliosis
Interventions
Spinal Fusion
Procedure
Lead sponsor
University of Colorado, Denver
Other
Eligibility
8 Years to 21 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 9, 2026, 12:53 AM EDT
Completed Phase 3 Interventional

IRB-HSR# 14145 R,S Methadone: Analgesia and Pharmacokinetics in Adolescents Undergoing Scoliosis Correction

NCT01205256
View directory record Official record
Conditions
Scoliosis
Interventions
methadone
Drug
Lead sponsor
University of Virginia
Other
Eligibility
12 Years to 19 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Oct 9, 2026, 12:53 AM EDT
Active, not recruiting Not applicable Interventional

Hospital-Based Cluster Trial: Magnetically Controlled Growing Rods Using Distraction Intervals

NCT04058561
View directory record Official record
Conditions
Early-Onset Scoliosis Deformity of Spine
Interventions
MAGEC® Spinal Bracing And Distraction System
Device
Lead sponsor
Pediatric Spine Foundation
Other
Eligibility
5 Years to 9 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
17
States / cities
Los Angeles, California • San Diego, California • Aurora, Colorado + 13 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 9, 2026, 12:53 AM EDT