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ClinicalTrials.gov public records Last synced Oct 4, 2026, 6:41 PM EDT

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Showing 1–24 of 79 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Scoliosis; Adolescence Clear all
Not listed No phase listed Observational Accepts healthy volunteers

Safety and Efficacy Study of Spinal Tethering

NCT02897453
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
The Spinal Tethering System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
10 Years to 23 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

3-D Correction of Adolescent Idiopathic Scoliosis (AIS) With Differential Metals

NCT05631821
View directory record Official record
Conditions
Juvenile and Adolescent Idiopathic Scoliosis
Interventions
differential rod bending with rod contours (MESA Spinal System)
Procedure
Lead sponsor
Rush University Medical Center
Other
Eligibility
10 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 2, 2022 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational

Bracing Compliance and Personality Traits: A Compliance Assessment Program for Scoliosis and Clubfeet

NCT02755766
View directory record Official record
Conditions
Clubfeet, Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
1 Day to 99 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational

Preemptive Genotyping and Pain Management

NCT01813695
View directory record Official record
Conditions
Pain
Interventions
Preemptive genotyping in medical record, Genotyping not included in electronic medical record
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 21 Years
Enrollment
576 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Use of Ultrasonic Bone Scalpel in Adolescent Idiopathic Scoliosis

NCT02781324
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Posterior Spinal Fusion
Interventions
Posterior Spinal Fusion, Ultrasonic Bone Scalpel
Procedure · Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Phase 4 Interventional Results available

Oral Caffeine Use for Pain Management in AIS Patients After Spinal Fusion

NCT04950660
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Caffeine Tablet, Placebo
Drug
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
12 Years to 17 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Feb 21, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional

SIMDiscovery: The Benefits of Utilizing a Simulation Preparation Program for Spinal Fusion Surgery

NCT03835390
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent
Interventions
SIMDiscovery
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 18 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 7, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Early Phase 1 Interventional

Medrol Dose Packs for Post-Operative Pain Control

NCT06453083
View directory record Official record
Conditions
Pain
Interventions
Placebo, Medrol
Drug
Lead sponsor
University of Utah
Other
Eligibility
10 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Phase 3 Interventional

The Effect of Erector Spinae Plane Block (ESPB) on Pediatric Pain Management Following Posterior Spinal Fusion (PSF) Surgery

NCT07561827
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis (AIS), Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Ropivacaine Hydrocloride
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
10 Years to 18 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional

Brace Monitoring for Adolescent Idiopathic Scoliosis (AIS)

NCT03292601
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
NYRC Brace Scoliosis Monitor
Device
Lead sponsor
Columbia University
Other
Eligibility
8 Years to 17 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Does Tranexamic Acid Decrease Blood Loss in Pediatric Idiopathic Scoliosis Surgery?

NCT01813058
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
10 Years to 21 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2019 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional

A Study to Evaluate a New Semi-rigid Brace, the RESILIENT Brace by Thinks Works, as a Way to Limit Curve Worsening in Kids With Idiopathic Scoliosis.

NCT07574632
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
The RESILIENT scoliosis brace system
Device
Lead sponsor
Thinks Works, PBC
Industry
Eligibility
9 Years to 16 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Terminated Phase 4 Interventional Results available

IV Lidocaine in Pediatric AIS

NCT03893318
View directory record Official record
Conditions
Systemic Lidocaine Improves Pain Control After Surgery by Attenuating the Systemic Inflammatory Response to Surgery
Interventions
IV lidocaine, Placebos
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting No phase listed Observational

Scoliosis Survey to Development Treatment Decision Tool

NCT03017755
View directory record Official record
Conditions
Scoliosis; Adolescence
Interventions
Survey for Patients Treated for Scoliosis and ther Families
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years and older
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 2, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Not yet recruiting Phase 4 Interventional

Postoperative Steroid Use in Adolescent Idiopathic Scoliosis and Neuromuscular Scoliosis Patients

NCT06023043
View directory record Official record
Conditions
Neuromuscular Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Dexamethasone
Drug
Lead sponsor
Children's Hospital Los Angeles
Other
Eligibility
9 Years to 18 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Terminated No phase listed Observational

Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis

NCT02084264
View directory record Official record
Conditions
Scoliosis
Interventions
Not listed
Lead sponsor
Mazor Robotics
Industry
Eligibility
10 Years to 21 Years
Enrollment
272 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
San Diego, California • Orlando, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Not applicable Interventional Results available

Green Sun Medical Dynamic Scoliosis Brace

NCT03641469
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Green Sun Dynamic Brace
Device
Lead sponsor
Green Sun medical
Industry
Eligibility
10 Years to 15 Years · Female only
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
7
States / cities
Los Angeles, California • Pasadena, California • Sacramento, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational

Prospective Study of Motion Preservation Evaluation Below Fusions of the Spine in Adolescent Idiopathic Scoliosis

NCT01661998
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
Not listed
Lead sponsor
Setting Scoliosis Straight Foundation
Other
Eligibility
8 Years to 21 Years
Enrollment
273 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
3
States / cities
San Diego, California • New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 4, 2026, 6:41 PM EDT
Terminated Not applicable Interventional Results available

Study of the Braive Growth Modulation System for Progressive Pediatric Scoliosis

NCT04929678
View directory record Official record
Conditions
Juvenile Idiopathic Scoliosis, Adolescent Idiopathic Scoliosis
Interventions
Braive™ Growth Modulation System (Braive™ GMS)
Device
Lead sponsor
Medtronic Spinal and Biologics
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 20, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Recruiting Not applicable Interventional

Rethinking Rigidity: Development of a 3D-Printed Scoliosis Brace With Varying Flexibility

NCT06785207
View directory record Official record
Conditions
Scoliosis Idiopathic Adolescent Treatment
Interventions
3D-printed scoliosis brace
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
8 Years to 18 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Houston, Texas • The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational

Pharmacokinetics of Aminocaproic Acid in Scoliosis Surgery

NCT01408823
View directory record Official record
Conditions
Scoliosis
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
8 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2013 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational

Return to Sport After Posterior Spinal Fusion

NCT03513120
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis, Posterior Spinal Fusion
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 19, 2020 · Synced Oct 4, 2026, 6:41 PM EDT
Completed Phase 2 Interventional Results available

Methadone vs Magnesium in Spinal Fusion

NCT01795495
View directory record Official record
Conditions
Idiopathic Scoliosis
Interventions
Methadone hydrochloride, Magnesium Sulfate, Remifentanil
Drug
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
12 Years to 19 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 8, 2018 · Synced Oct 4, 2026, 6:41 PM EDT
Completed No phase listed Observational Results available

Adolescent Idiopathic Scoliosis (AIS) Patient Positioning in EOS System®

NCT02269657
View directory record Official record
Conditions
Adolescent Idiopathic Scoliosis
Interventions
EOS® imaging system
Device
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
10 Years to 18 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 13, 2017 · Synced Oct 4, 2026, 6:41 PM EDT