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ClinicalTrials.gov public records Last synced Sep 22, 2026, 12:21 AM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Screening for Colon Cancer Clear all
Completed No phase listed Observational Accepts healthy volunteers

Blood Collection Sub-Study of Exact Sciences Protocol 2019-01: "Clinical Validation of an Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, For Colorectal Cancer Screening BLUE-C"

NCT04144751
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Blood Sample Collection
Other
Lead sponsor
Exact Sciences Corporation
Industry
Eligibility
40 Years and older
Enrollment
23,494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
194
States / cities
Birmingham, Alabama • Cullman, Alabama • Dothan, Alabama + 160 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Sep 22, 2026, 12:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Complete Histologic Resection of Adenomatous Polyps?

NCT01224444
View directory record Official record
Conditions
Adenomatous Polyps
Interventions
standard polypectomy snare
Other
Lead sponsor
White River Junction Veterans Affairs Medical Center
Federal
Eligibility
40 Years to 85 Years
Enrollment
269 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
2
States / cities
Lebanon, New Hampshire • White River Junction, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 11, 2015 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chromocolonoscopy for the Detection of Flat Adenomas in Routine Colorectal Cancer Screening.

NCT00245492
View directory record Official record
Conditions
Colon Cancer, Polyp, Adenoma
Interventions
Chromocolonoscopy
Procedure
Lead sponsor
Indiana University
Other
Eligibility
50 Years and older
Enrollment
792 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
3
States / cities
Indianapolis, Indiana • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jan 27, 2009 · Synced Sep 22, 2026, 12:21 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Multilevel Approach for Improvement in Screening of Colorectal Cancer in Rural Communities, The Screen to Save Trial

NCT05291988
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Educational Intervention, Fecal Immunochemical Test, Questionnaire Administration
Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
2
States / cities
Seattle, Washington • Sequim, Washington
Source: ClinicalTrials.gov public record
Updated Dec 14, 2022 · Synced Sep 22, 2026, 12:21 AM EDT
Terminated Not applicable Interventional Results available

Outreach for Patients That Are Newly Eligible for Colorectal Cancer Screening

NCT00860249
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Letter Only, Letter and Educational DVD
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
50 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 4, 2011 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Genetic Epidemiology Risk Assessment Program or Usual Care in Colorectal Cancer Screening for Healthy Participants

NCT00478309
View directory record Official record
Conditions
Colorectal Cancer, Healthy, no Evidence of Disease
Interventions
counseling intervention, educational intervention
Other
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
50 Years and older
Enrollment
697 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 2, 2016 · Synced Sep 22, 2026, 12:21 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

A Prospective Study of a New Immunochemical Fecal Occult Blood Test in U.S. Veteran Patients Undergoing Colonoscopy

NCT00533975
View directory record Official record
Conditions
Colon Cancer
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2007 · Synced Sep 22, 2026, 12:21 AM EDT
Terminated No phase listed Observational Results available

Genetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE Trial

NCT03765736
View directory record Official record
Conditions
Metastatic Colon Adenocarcinoma, Metastatic Rectal Adenocarcinoma, Stage III Colon Cancer AJCC v8, Stage III Rectal Cancer AJCC v8, Stage IIIA Colon Cancer AJCC v8, Stage IIIA Rectal Cancer AJCC v8, Stage IIIB Colon Cancer AJCC v8, Stage IIIB Rectal Cancer AJCC v8, Stage IIIC Colon Cancer AJCC v8, Stage IIIC Rectal Cancer AJCC v8, Stage IV Colon Cancer AJCC v8, Stage IV Rectal Cancer AJCC v8, Stage IVA Colon Cancer AJCC v8, Stage IVA Rectal Cancer AJCC v8, Stage IVB Colon Cancer AJCC v8, Stage IVB Rectal Cancer AJCC v8, Stage IVC Colon Cancer AJCC v8, Stage IVC Rectal Cancer AJCC v8, Unresectable Colon Adenocarcinoma, Unresectable Rectal Adenocarcinoma
Interventions
Genetic Testing
Other
Lead sponsor
Academic and Community Cancer Research United
Other
Eligibility
18 Years and older
Enrollment
199 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
18
States / cities
Scottsdale, Arizona • La Jolla, California • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2025 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Colonoscopy or Fecal Occult Blood Test in Screening Healthy Participants for Colorectal Cancer

NCT00102011
View directory record Official record
Conditions
Colorectal Cancer
Interventions
annual screening, fecal occult blood test, screening colonoscopy, standard follow-up care
Procedure
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
40 Years to 69 Years
Enrollment
4,952 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2026
U.S. locations
4
States / cities
Shreveport, Louisiana • Minneapolis, Minnesota • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2026 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colorectal Cancer Screening Navigator Program for Low Income and Non-English Speaking Populations

NCT00476970
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Patient Navigation
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
52 Years to 79 Years
Enrollment
1,223 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Chelsea, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2016 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional

Randomized Controlled Trial Comparing Water vs. Air Method for Performing Colonoscopy in Adult Female Subjects

NCT01790425
View directory record Official record
Conditions
Screening for Colon Cancer
Interventions
to infuse water into colon to open the lumen for water infusion colonoscopy, Air colonoscopy
Procedure
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 80 Years · Female only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jun 26, 2017 · Synced Sep 22, 2026, 12:21 AM EDT
Completed No phase listed Observational

Combined Colon and Endometrial Cancer Screening in Women With HNPCC

NCT00510796
View directory record Official record
Conditions
Colon Cancer
Interventions
Interview
Behavioral
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2016 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Educational Intervention With or Without Telephone Counseling in Increasing Colorectal Cancer Screening Compliance in Brothers and Sisters of Patients With Colorectal Cancer

NCT00352638
View directory record Official record
Conditions
Colorectal Cancer
Interventions
counseling intervention, educational intervention, study of socioeconomic and demographic variables
Other
Lead sponsor
Fox Chase Cancer Center
Other
Eligibility
40 Years and older
Enrollment
660 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2013
U.S. locations
18
States / cities
Newark, Delaware • Washington D.C., District of Columbia • Tampa, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated May 15, 2014 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC

NCT04890054
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Fecal Immunochemical Test, Interview, Patient Navigation
Other · Behavioral
Lead sponsor
OHSU Knight Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
5,696 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 18, 2025 · Synced Sep 22, 2026, 12:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Vanguard Study: Testing a New Way to Screen for Cancer

NCT06995898
View directory record Official record
Conditions
Bladder Carcinoma, Breast Carcinoma, Colorectal Carcinoma, Esophageal Carcinoma, Gastric Carcinoma, Liver Carcinoma, Lung Carcinoma, Malignant Solid Neoplasm, Ovarian Carcinoma, Pancreatic Carcinoma, Prostate Carcinoma
Interventions
Biospecimen Collection, Device Usage, Electronic Health Record Review, Multi-Cancer Detection Test, Questionnaire Administration
Procedure · Device · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
45 Years to 75 Years
Enrollment
24,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
44
States / cities
Pleasanton, California • Cheyenne Wells, Colorado • Denver, Colorado + 36 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Rural Colon Cancer Screening Toolkit Intervention

NCT04651504
View directory record Official record
Conditions
Colon Cancer Screening
Interventions
Colorectal Cancer Toolkit
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
45 Years to 75 Years
Enrollment
185,903 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 4, 2026 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lay Health Worker Outreach in Increasing Colorectal Cancer Screening in Asian Americans

NCT03115372
View directory record Official record
Conditions
Colorectal Carcinoma, Health Status Unknown, Healthy Subject
Interventions
Educational Intervention, Informational Intervention, Survey Administration, Telephone-Based Intervention
Other · Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
50 Years to 75 Years
Enrollment
982 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
4
States / cities
Los Angeles, California • Sacramento, California • San Francisco, California + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Sep 22, 2026, 12:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluating Online Messages About Colon Cancer Screening

NCT06134089
View directory record Official record
Conditions
Colonic Cancer
Interventions
Perceived Effectiveness Prompt, Perceived Shareability Prompt
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
45 Years to 74 Years
Enrollment
2,210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Standard Colonoscopy Versus Colonoscopy With Endocuff Vision

NCT03361917
View directory record Official record
Conditions
Colorectal Polyp, Colorectal Adenoma, Colon Cancer
Interventions
Endocuff Vision
Device
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional

Comparative Effectiveness of FIT, Colonoscopy, & Usual Care Screening Strategies

NCT01710215
View directory record Official record
Conditions
Colorectal Cancer
Interventions
FIT Screening Strategy, Colon Screening Strategy
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 64 Years
Enrollment
5,999 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Health Service Intervention for the Improvement of Access and Adherence to Colorectal Cancer Screening

NCT04607291
View directory record Official record
Conditions
Colorectal Carcinoma
Interventions
Community Health Service, Survey Administration
Other
Lead sponsor
Roswell Park Cancer Institute
Other
Eligibility
50 Years to 75 Years
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2021 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Low Literacy Intervention for Colorectal Cancer Screening

NCT00012922
View directory record Official record
Conditions
Colorectal Cancer
Interventions
Low Literacy Intervention for Colorectal Cancer Screening
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years and older · Male only
Enrollment
2,400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Ends 2003
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 6, 2015 · Synced Sep 22, 2026, 12:21 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Plasma-based Colorectal Cancer Screening Research & Development

NCT04027790
View directory record Official record
Conditions
Colo-rectal Cancer
Interventions
Epi proColon
Diagnostic Test
Lead sponsor
Epigenomics, Inc
Industry
Eligibility
45 Years to 84 Years
Enrollment
354 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
5
States / cities
Tampa, Florida • Springfield, Illinois • New Orleans, Louisiana + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 1, 2021 · Synced Sep 22, 2026, 12:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Colonoscopy Screening: Setting Epic Follow-up Times

NCT05631873
View directory record Official record
Conditions
Concordance Between Colonoscopy Follow up Interval Noted in Patient Letters vs. Electronic Health Record Chart, Colorectal Cancer
Interventions
Assistance with implementing Epic Smartlist
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
Not listed
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Sep 22, 2026, 12:21 AM EDT