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ClinicalTrials.gov public records Last synced Jul 22, 2026, 11:48 AM EDT

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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Second Degree Burn Clear all
Not listed Phase 1 Interventional

Using Autologous Platelet Rich Plasma (PRP) Gel to Treat Deep 2nd and 3rd Degree Burns

NCT01843686
View directory record Official record
Conditions
Acute Burns
Interventions
Magellan®, Placebo Saline Gel and Usual and Customary Standard of Care
Device · Other
Lead sponsor
Arteriocyte, Inc.
Industry
Eligibility
18 Years to 86 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Sacramento, California • Washington D.C., District of Columbia • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Not applicable Interventional Results available

An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.

NCT01734317
View directory record Official record
Conditions
Wound Healing
Interventions
Mepilex Transfer Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Tampa, Florida • Garden City, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Not applicable Interventional Results available

NPWT PRO vs KCI Ulta® NPWT and to Compare NPWT PRO vs NPWT PRO With Simultaneous Irrigation on Wound Healing

NCT02519621
View directory record Official record
Conditions
Partial-thickness Burn, Ulcer
Interventions
NPWT PRO without irrigation, NPWT PRO with irrigation, KCI Ulta
Device
Lead sponsor
Larry Lavery
Other
Eligibility
18 Years to 89 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Jul 22, 2026, 11:48 AM EDT
Terminated Phase 4 Interventional Results available

Superficial Partial-Thickness Burn Study

NCT04601532
View directory record Official record
Conditions
Superficial Partial Thickness Burn
Interventions
Catasyn™ Advanced Technology Hydrogel and SynePure™ Wound Cleanser, Silver Sulfadiazine
Device · Drug
Lead sponsor
J. Peter Rubin, MD
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Phase 3 Interventional Results available

StrataGraft® Skin Tissue Expanded Access at Specific Study Sites ( StrataCAT )

NCT04123548
View directory record Official record
Conditions
Deep Partial-thickness Burn
Interventions
StrataGraft skin tissue
Biological
Lead sponsor
Stratatech, a Mallinckrodt Company
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
10
States / cities
Orange, California • Washington D.C., District of Columbia • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Jul 22, 2026, 11:48 AM EDT
Withdrawn Phase 1 Interventional

Polymem vs. Bacitracin/Xeroform in Treating Burn Wounds

NCT00479193
View directory record Official record
Conditions
Burns
Interventions
bacitracin/xeroform, Polymem
Drug
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Jul 22, 2026, 11:48 AM EDT
Not listed Phase 2 Interventional

Safety and Efficacy Study of Autologous Engineered Skin Substitute to Treat Partial- and Full-Thickness Burn Wounds

NCT01655407
View directory record Official record
Conditions
Thermal Injury, Deep Partial-Thickness Burn, Full-Thickness Burn
Interventions
Autologous Engineered Skin Substitute, Split-Thickness Autograft (AG)
Drug
Lead sponsor
Amarantus BioScience Holdings, Inc.
Industry
Eligibility
18 Years to 40 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Pheonix, Arizona • Houston, Texas • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 30, 2016 · Synced Jul 22, 2026, 11:48 AM EDT
Active, not recruiting Not applicable Interventional

Randomized Controlled Trial to Investigate Clinical Outcomes and Associated Costs When PermeaDerm is Used as Temporary Dressing for Surgical Wounds

NCT06750809
View directory record Official record
Conditions
Surgical Wound, Trauma Wound, Autografts, Partial-thickness Burn, Partial Thickness Wounds
Interventions
PermeaDerm Biosynthetic Wound Matrix, Frozen Human Cadaveric Allograft (FHCA)
Device
Lead sponsor
Avita Medical
Industry
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Phoenix, Arizona • Washington D.C., District of Columbia • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 22, 2026, 11:48 AM EDT
Withdrawn Not applicable Interventional

Mepilex Ag vs. Xeroform in Pediatric Patients That Sustain Partial Thickness Burn Injury

NCT04149808
View directory record Official record
Conditions
Second-degree Burn
Interventions
Mepilex Ag (burn dressing), Xeroform Dressing
Device
Lead sponsor
Wayne State University
Other
Eligibility
7 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Stem Cell Therapy to Improve Burn Wound Healing

NCT02104713
View directory record Official record
Conditions
Skin Burn Degree Second
Interventions
Allogeneic (MSC's) Application to the Burn Wounds
Biological
Lead sponsor
E.Badiavas
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Jul 22, 2026, 11:48 AM EDT
Not listed Phase 1 Interventional

CellMist™ Autologous Cells to Treat Deep Second-Degree Burns

NCT04890574
View directory record Official record
Conditions
Burns, Burns Second Degree, Burns Deep Second Degree
Interventions
CellMist™ System
Device
Lead sponsor
RenovaCare, Inc
Industry
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 14, 2022 · Synced Jul 22, 2026, 11:48 AM EDT
Terminated Phase 4 Interventional

Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients

NCT01574131
View directory record Official record
Conditions
Second or Third Degree Burns
Interventions
Fenofibrate, Sugar Pill
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
4 Years to 20 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2019 · Synced Jul 22, 2026, 11:48 AM EDT
Not listed Phase 1 Interventional

Applying Platelet Rich Plasma (PRP) Gel to Acute Deep Partial Thickness Thermal Injuries

NCT02169362
View directory record Official record
Conditions
Acute Deep Partial Thickness Thermal Burns
Interventions
Autologous Platelet Rich Plasma (PRP) Gel (Magellan® Bio-Bandage™)
Device
Lead sponsor
Arteriocyte, Inc.
Industry
Eligibility
18 Years to 86 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
8
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2017 · Synced Jul 22, 2026, 11:48 AM EDT
Withdrawn Phase 2Phase 3 Interventional

Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds

NCT01790763
View directory record Official record
Conditions
Skin Burn Degree Second
Interventions
Keramatrix, Mepilex
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
1 Day to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2015 · Synced Jul 22, 2026, 11:48 AM EDT
Terminated Phase 4 Interventional Results available

Comparison of Collagenase With Antibiotic Ointment of Minor Partial Thickness Burns

NCT02673229
View directory record Official record
Conditions
Burn, Partial Thickness
Interventions
Collagenase Santyl, Bacitracin
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
2 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Not applicable Interventional Results available

ReCell® Combined With Meshed Skin Graft in the Treatment of Acute Burn Injuries

NCT02380612
View directory record Official record
Conditions
Burns
Interventions
ReCell Treatment, Skin Graft
Device · Procedure
Lead sponsor
Avita Medical
Industry
Eligibility
5 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
7
States / cities
Phoenix, Arizona • Washington D.C., District of Columbia • Tampa, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Jul 22, 2026, 11:48 AM EDT
Terminated Not applicable Interventional Results available

Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns

NCT03564795
View directory record Official record
Conditions
Partial-thickness Burn
Interventions
KeraStat Gel, Silver Sulfadiazine
Device
Lead sponsor
KeraNetics, LLC
Industry
Eligibility
6 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Not applicable Interventional Results available

A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries

NCT01138917
View directory record Official record
Conditions
Burns
Interventions
ReCell and Split-thickness skin graft
Device
Lead sponsor
Avita Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
12
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 9 more
Source: ClinicalTrials.gov public record
Updated May 12, 2019 · Synced Jul 22, 2026, 11:48 AM EDT
Recruiting Phase 2 Interventional

4-Aminopyridine to Treat Skin Burns

NCT06596434
View directory record Official record
Conditions
Burns, Second Degree Burn, Wounds and Injuries
Interventions
Drug: 4-Aminopyridine, Placebo
Drug · Other
Lead sponsor
John Elfar
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 22, 2026, 11:48 AM EDT
Not yet recruiting Not applicable Interventional

Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients.

NCT07453732
View directory record Official record
Conditions
Partial-thickness Burn, Pain, Second Degree Burn
Interventions
Banana leaf dressing
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 23, 2026 · Synced Jul 22, 2026, 11:48 AM EDT
Recruiting Phase 2 Interventional

Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

NCT01297400
View directory record Official record
Conditions
Burns
Interventions
Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]
Drug
Lead sponsor
Skingenix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Not applicable Interventional Results available

Evaluating the Cost-effectiveness, Efficacy, Safety and Tolerance of Mepilex® Ag Versus Silvadene®

NCT00742183
View directory record Official record
Conditions
Second Degree Burn
Interventions
Mepilex, Silvadene
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
5 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
10
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Gainesville, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Jul 22, 2026, 11:48 AM EDT
Recruiting Not applicable Interventional

Field Shield Wound Dressing Study

NCT07337616
View directory record Official record
Conditions
Burn Wounds - Partial Thickness (2nd Degree)
Interventions
Field Shield Wound Dressing, Silverlon
Device
Lead sponsor
KeriCure Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jul 22, 2026, 11:48 AM EDT
Completed Phase 4 Interventional

Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns

NCT01926392
View directory record Official record
Conditions
Burn
Interventions
water-soluble therapy, silver sulfadiazine
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Jul 22, 2026, 11:48 AM EDT