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ClinicalTrials.gov public records Last synced Sep 4, 2026, 7:20 PM EDT

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Showing 1–24 of 35 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Second-degree Burn Clear all
Withdrawn Phase 1 Interventional

Polymem vs. Bacitracin/Xeroform in Treating Burn Wounds

NCT00479193
View directory record Official record
Conditions
Burns
Interventions
bacitracin/xeroform, Polymem
Drug
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2017 · Synced Sep 4, 2026, 7:20 PM EDT
Not listed Phase 1 Interventional

Using Autologous Platelet Rich Plasma (PRP) Gel to Treat Deep 2nd and 3rd Degree Burns

NCT01843686
View directory record Official record
Conditions
Acute Burns
Interventions
Magellan®, Placebo Saline Gel and Usual and Customary Standard of Care
Device · Other
Lead sponsor
Arteriocyte, Inc.
Industry
Eligibility
18 Years to 86 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
3
States / cities
Sacramento, California • Washington D.C., District of Columbia • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 8, 2018 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Not applicable Interventional Results available

NPWT PRO vs KCI Ulta® NPWT and to Compare NPWT PRO vs NPWT PRO With Simultaneous Irrigation on Wound Healing

NCT02519621
View directory record Official record
Conditions
Partial-thickness Burn, Ulcer
Interventions
NPWT PRO without irrigation, NPWT PRO with irrigation, KCI Ulta
Device
Lead sponsor
Larry Lavery
Other
Eligibility
18 Years to 89 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2023 · Synced Sep 4, 2026, 7:20 PM EDT
Recruiting Not applicable Interventional

Field Shield Wound Dressing Study

NCT07337616
View directory record Official record
Conditions
Burn Wounds - Partial Thickness (2nd Degree)
Interventions
Field Shield Wound Dressing, Silverlon
Device
Lead sponsor
KeriCure Medical
Industry
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Phoenix, Arizona • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Sep 4, 2026, 7:20 PM EDT
Recruiting Phase 2 Interventional

4-Aminopyridine to Treat Skin Burns

NCT06596434
View directory record Official record
Conditions
Burns, Second Degree Burn, Wounds and Injuries
Interventions
Drug: 4-Aminopyridine, Placebo
Drug · Other
Lead sponsor
John Elfar
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Sep 4, 2026, 7:20 PM EDT
Enrolling by invitation Phase 4 Interventional

Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns

NCT07326657
View directory record Official record
Conditions
Partial-thickness Burn Wounds
Interventions
Intact fish skin graft, autograft
Device · Procedure
Lead sponsor
Kerecis Ltd.
Industry
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Phase 4 Interventional Results available

Open, Prosp, Rand. Invest. Evaluating Pain With Mepitel One vs.Bridal Veil and Staples on Split Thickness Skin Grafts

NCT01365273
View directory record Official record
Conditions
Deep Partial Thickness Burn, Full Thickness Burns
Interventions
Mepitel One
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years to 70 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
4
States / cities
Tampa, Florida • Augusta, Georgia • Kansas City, Kansas + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2014 · Synced Sep 4, 2026, 7:20 PM EDT
Terminated Phase 4 Interventional

Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients

NCT01574131
View directory record Official record
Conditions
Second or Third Degree Burns
Interventions
Fenofibrate, Sugar Pill
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
4 Years to 20 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 28, 2019 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Not applicable Interventional Results available

A Multicenter Comparative Study of the ReCell Device and Autologous Split-thickness Meshed Skin Graft in the Treatment of Acute Burn Injuries

NCT01138917
View directory record Official record
Conditions
Burns
Interventions
ReCell and Split-thickness skin graft
Device
Lead sponsor
Avita Medical
Industry
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
12
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 9 more
Source: ClinicalTrials.gov public record
Updated May 12, 2019 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Not applicable Interventional

A Randomized Trial Evaluating EARLY Application of a Surfactant Dressing in Thermal Injury (EARLY)

NCT04880655
View directory record Official record
Conditions
Burns, Partial-thickness Burn
Interventions
WSD, Dressed with bacitracin and petrolatum gauze
Device
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Sep 4, 2026, 7:20 PM EDT
Active, not recruiting Not applicable Interventional

Randomized Controlled Trial to Investigate Clinical Outcomes and Associated Costs When PermeaDerm is Used as Temporary Dressing for Surgical Wounds

NCT06750809
View directory record Official record
Conditions
Surgical Wound, Trauma Wound, Autografts, Partial-thickness Burn, Partial Thickness Wounds
Interventions
PermeaDerm Biosynthetic Wound Matrix, Frozen Human Cadaveric Allograft (FHCA)
Device
Lead sponsor
Avita Medical
Industry
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
13
States / cities
Phoenix, Arizona • Washington D.C., District of Columbia • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 4, 2026, 7:20 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Ultrasound Treatment on Wound Healing Time

NCT05796492
View directory record Official record
Conditions
Burn Wound, 2nd Degree Burn of the Skin
Interventions
Pulsed splenic ultrasound, Ultrasound probe (no energy applied)
Device
Lead sponsor
General Electric Research
Industry
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2025 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Not applicable Interventional Results available

An Open Single-centre Investigation Evaluating Efficacy in Second Degree Partial Thickness Burns Using a Silicone Contact Layer Containing Silver.

NCT01734317
View directory record Official record
Conditions
Wound Healing
Interventions
Mepilex Transfer Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Tampa, Florida • Garden City, New York
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Stem Cell Therapy to Improve Burn Wound Healing

NCT02104713
View directory record Official record
Conditions
Skin Burn Degree Second
Interventions
Allogeneic (MSC's) Application to the Burn Wounds
Biological
Lead sponsor
E.Badiavas
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2020 · Synced Sep 4, 2026, 7:20 PM EDT
Terminated Not applicable Interventional Results available

Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns

NCT03564795
View directory record Official record
Conditions
Partial-thickness Burn
Interventions
KeraStat Gel, Silver Sulfadiazine
Device
Lead sponsor
KeraNetics, LLC
Industry
Eligibility
6 Years to 100 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 31, 2024 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Phase 4 Interventional

Comparison of a Water-soluble Topical Antimicrobial to Silver Sulfadiazine in Partial Thickness Burns

NCT01926392
View directory record Official record
Conditions
Burn
Interventions
water-soluble therapy, silver sulfadiazine
Drug
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Sep 4, 2026, 7:20 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Compare the Efficacy of Mepilex and Keramatrix in Second Degree Burn Wounds

NCT01790763
View directory record Official record
Conditions
Skin Burn Degree Second
Interventions
Keramatrix, Mepilex
Device
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
1 Day to 18 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 13, 2015 · Synced Sep 4, 2026, 7:20 PM EDT
Completed No phase listed Observational

Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C

NCT05612867
View directory record Official record
Conditions
Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second, Burn Degree Third, Fluid and Electrolyte Imbalance
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
Arrowhead Regional Medical Center
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Colton, California
Source: ClinicalTrials.gov public record
Updated Nov 9, 2022 · Synced Sep 4, 2026, 7:20 PM EDT
Active, not recruiting Not applicable Interventional

Performance and Safety of Exufiber Ag+ and Exufiber on Partial Thickness Burns

NCT04839523
View directory record Official record
Conditions
Partial-thickness Burn
Interventions
Exufiber, Exufiber Ag+
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
4 Weeks and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
6
States / cities
Phoenix, Arizona • Los Angeles, California • Washington D.C., District of Columbia + 3 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2024 · Synced Sep 4, 2026, 7:20 PM EDT
Recruiting Phase 2 Interventional

Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

NCT01297400
View directory record Official record
Conditions
Burns
Interventions
Investigational Drug, MW-III, Silvadene® Cream 1% [Silver Sulfadiazine]
Drug
Lead sponsor
Skingenix, Inc.
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Sacramento, California • Washington D.C., District of Columbia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 4, 2026, 7:20 PM EDT
Terminated No phase listed Observational

Utilizing 3D Imaging for Burn Wound Assessment

NCT06938061
View directory record Official record
Conditions
Burn, 2nd Degree Burn of the Skin, 3rd Degree Burn of the Skin, 1st Degree Burn of the Skin
Interventions
3D Imaging
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
18 Years to 89 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Sep 4, 2026, 7:20 PM EDT
Terminated Phase 4 Interventional Results available

Comparison of Collagenase With Antibiotic Ointment of Minor Partial Thickness Burns

NCT02673229
View directory record Official record
Conditions
Burn, Partial Thickness
Interventions
Collagenase Santyl, Bacitracin
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
2 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2024 · Synced Sep 4, 2026, 7:20 PM EDT
Recruiting Phase 3 Interventional

Safety and Efficacy of realSKIN® to Provide Complete Wound Closure of Burn Wounds as an Alternative to Autografting

NCT06223269
View directory record Official record
Conditions
Burns Degree Third, Burn (Disorder), Burn Degree Second, Thermal Burn, Wound Heal
Interventions
Skin Xenotransplant, Autograft(ing)
Drug · Procedure
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
4
States / cities
Phoenix, Arizona • Augusta, Georgia • Portland, Maine + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 4, 2026, 7:20 PM EDT
Completed Not applicable Interventional Results available

A Clinical Investigation to Evaluate Efficacy of Mepitel Ag in Partial Thickness Second Degree Burns

NCT01636362
View directory record Official record
Conditions
Burns, Wound Healing
Interventions
Mepitel Ag
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
2 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
6
States / cities
Phoenix, Arizona • Orlando, Florida • Indianapolis, Indiana + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 6, 2014 · Synced Sep 4, 2026, 7:20 PM EDT