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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sedation, Conscious Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

NCT03653520
View directory record Official record
Conditions
Cataract
Interventions
Diazepam, Tramadol, Ondansetron, MKO melt
Drug
Lead sponsor
Avanti Anesthesia
Other
Eligibility
18 Years and older
Enrollment
651 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 30, 2018 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Using Capnography to Reduce Hypoxia During Pediatric Sedation

NCT01463527
View directory record Official record
Conditions
Hypoventilation, Hypoxia
Interventions
Nellcor NPB-70 Capnograph
Device
Lead sponsor
Yale University
Other
Eligibility
1 Year to 20 Years
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 10, 2018 · Synced Jul 22, 2026, 2:08 PM EDT
Enrolling by invitation Phase 1 Interventional Accepts healthy volunteers

Induction of Dreaming With EEG and Anesthesia in Healthy Adults

NCT07198711
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Propofol - Emergence-from-LOR Protocol, Propofol - Light Sedation Protocol
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 3 Interventional

An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Colonoscopy

NCT00261599
View directory record Official record
Conditions
Conscious Sedation
Interventions
AQUAVAN® (fospropofol disodium) Injection, Midazolam HCI
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
20
States / cities
Huntsville, Alabama • Fresno, California • Jacksonville, Florida + 17 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2008 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sedation for Brainstem Evoked Auditory Response (BEAR) Testing Using Intravenous Pentobarbital

NCT01282112
View directory record Official record
Conditions
Childrens 0 to 18 Years of Age Who Require Moderate Sedation
Interventions
Not listed
Lead sponsor
Akron Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
416 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Akron, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy

NCT06181188
View directory record Official record
Conditions
Conscious Sedation, Patient Satisfaction, Ketamine
Interventions
Ketamine, Midazolam, Fentanyl
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 25, 2023 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Flumazenil Reversal of Oral Triazolam

NCT00695630
View directory record Official record
Conditions
Dental Anxiety
Interventions
Flumazenil, Placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 40 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jun 11, 2008 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated Phase 2 Interventional Results available

Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions

NCT01845441
View directory record Official record
Conditions
Stroke, Brain Ischemia, Vasospasm, Intracranial, Hemorrhage, Intracranial
Interventions
Dexmedetomidine, Fentanyl, Midazolam
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 27, 2022 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Gabapentin to Improve Patient Tolerance in Endoscopic Retrograde Cholangiopancreatography (ERCP)

NCT01143766
View directory record Official record
Conditions
Conscious Sedation
Interventions
Gabapentin, Standard sedation regimen
Drug · Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Use of Capnography in EGD and Colonoscopy With Moderate Sedation.

NCT01994785
View directory record Official record
Conditions
Hypoxia, Apnea, Hypotension, Hypopnea
Interventions
Capnographic Monitoring
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Independence, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Driving Skills Recovery Following Procedural Sedation for Gastrointestinal Endoscopy

NCT04350424
View directory record Official record
Conditions
Anesthesia, Psychomotor Status
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 17, 2023 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers Results available

Sedation Regimens in GI Endoscopy

NCT04807101
View directory record Official record
Conditions
Anesthesia, Endoscopy, Colonoscopy, Conscious Sedation
Interventions
midazolam alone
Drug
Lead sponsor
Greg S Cohen MD LLC
Other
Eligibility
18 Years to 75 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Moderate Sedation Educational Software

NCT00708760
View directory record Official record
Conditions
Moderate Sedation Training
Interventions
paper based training, web based training
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2012
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 22, 2026, 2:08 PM EDT
Not listed Not applicable Interventional

Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery Time

NCT02620501
View directory record Official record
Conditions
Dysphagia, GERD, Abdominal Pain
Interventions
Lidocaine, Placebo
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Jul 22, 2026, 2:08 PM EDT
Terminated Not applicable Interventional Results available

Bispectral Index Monitoring During Testing in the Electrophysiology Lab

NCT00749671
View directory record Official record
Conditions
Tachycardia, Ventricular
Interventions
Bispectral index monitoring, Ramsey Sedation Scale
Device · Other
Lead sponsor
Baystate Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Not applicable Interventional Results available

Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies

NCT02518919
View directory record Official record
Conditions
Conscious Sedation
Interventions
Child life intervention, Music listening
Other
Lead sponsor
Children's Hospital of Michigan
Other
Eligibility
3 Years to 15 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 26, 2018 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 3 Interventional

An Effectiveness and Safety Study of AQUAVAN® Injection (Fospropofol Disodium) for Sedation During Flexible Bronchoscopy

NCT00306722
View directory record Official record
Conditions
Bronchoscopy, Anesthesia
Interventions
AQUAVAN® (fospropofol disodium) Injection
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
25
States / cities
Mobile, Alabama • Phoenix, Arizona • Laguna Hills, California + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2008 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

Intranasal Midazolam in Children as a Pre-Operative Sedative

NCT02314546
View directory record Official record
Conditions
Sedation, Conscious
Interventions
Midazolam, xylocaine, saline placebo
Drug
Lead sponsor
Bassett Healthcare
Other
Eligibility
18 Months to 7 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Cooperstown, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2015 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Observational Results available

Cortisol Response to Moderate and Deep Sedation in Children

NCT01265966
View directory record Official record
Conditions
Adrenal Insufficiency
Interventions
Not listed
Lead sponsor
Tripler Army Medical Center
Federal
Eligibility
3 Months to 18 Years
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Honolulu, Hawaii
Source: ClinicalTrials.gov public record
Updated Mar 10, 2013 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Isolite and Dental Treatment Under Conscious Sedation

NCT01683851
View directory record Official record
Conditions
Dental Caries
Interventions
Isolite System
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
4 Years to 7 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 12, 2013 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA

NCT04305158
View directory record Official record
Conditions
Nitrous Oxide
Interventions
Nitrous Oxide
Drug
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Apr 10, 2024 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 2Phase 3 Interventional Results available

A Safety Study of AQUAVAN® (Fospropofol Disodium) Injection for Sedation During Minor Surgical Procedures.

NCT00327392
View directory record Official record
Conditions
Procedural Sedation
Interventions
AQUAVAN® (fospropofol disodium) Injection
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
15
States / cities
Phoenix, Arizona • Jacksonville, Florida • Louisville, Kentucky + 11 more
Source: ClinicalTrials.gov public record
Updated Jun 19, 2012 · Synced Jul 22, 2026, 2:08 PM EDT
Completed No phase listed Observational

Effect of Anesthesia on Force Application During Colonoscopy

NCT02101099
View directory record Official record
Conditions
Outpatient Colonoscopy for Colorectal Cancer Screening or for Symptoms Suggestive of Colonic Diseases
Interventions
Colonoscopy Force Monitor
Device
Lead sponsor
Artann Laboratories
Industry
Eligibility
30 Years to 75 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Washington D.C., District of Columbia • Chevy Chase, Maryland • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 11, 2016 · Synced Jul 22, 2026, 2:08 PM EDT
Completed Phase 4 Interventional Results available

A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency Department

NCT03085563
View directory record Official record
Conditions
Conscious Sedation, Simple Lacerations Less Than 4 cm, Lumbar Punctures, Minor Incision Drainage of Abscesses Not Requiring Extensive Debridement
Interventions
Nitrous Oxide, Midazolam
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
2 Years to 17 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Jul 22, 2026, 2:08 PM EDT