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Showing 1–24 of 728 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Self Destructive Behavior Clear all
Not listed Phase 3 Interventional

Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation

NCT01212848
View directory record Official record
Conditions
Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation - Sham Comparator
Device
Lead sponsor
INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Other
Eligibility
18 Years to 70 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
2
States / cities
Bethesda, Maryland • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2013 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Phase 1 Interventional

Emergency Linkage to Outpatient Psychiatric Services

NCT00278811
View directory record Official record
Conditions
Emergency Services, Psychiatric
Interventions
mobile crisis team
Procedure
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Jul 21, 2026, 5:27 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Inducing Self-Dehumanization to Examine Oxytocin and Suicide Risk

NCT06710964
View directory record Official record
Conditions
Mechanistic Self-Dehumanization Condition, Control Condition
Interventions
The Ten Item Personality Inventory, Mechanistic Self-Dehumanization Condition, Debrief, Control Condition, Clinical Interview, Self-Report Measures, Blood Draw
Other · Diagnostic Test
Lead sponsor
Florida State University
Other
Eligibility
18 Years to 40 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Recruiting Not applicable Interventional

A Novel Peer-Delivered Recovery-Focused Suicide Prevention Intervention for Veterans With Serious Mental Illness

NCT05537376
View directory record Official record
Conditions
Psychotic Disorders, Bipolar Disorders, Suicidal Ideation, Suicide, Attempted
Interventions
SUicide Prevention by Peers Offering Recovery Tactics
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Not applicable Interventional

Co-Designing a Virtual Reality Intervention to Enhance Skill Development

NCT07186543
View directory record Official record
Conditions
Suicide
Interventions
Cognitive Behavioral Therapy (CBT) Worksheets, Practice Experiences for School Reintegration (PrESR)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years to 18 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Suicide Prevention for Sexual and Gender Minority Youth (Randomized Controlled Trial)

NCT05669976
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention with Navigation Services, Safety Planning Intervention
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
15 Years to 29 Years
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Recruiting Not applicable Interventional

Development of PRECISE: A Data Driven Personalized Suicide Prevention Intervention

NCT06809348
View directory record Official record
Conditions
Suicidal Thoughts and Behaviors
Interventions
PRECISE
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Not applicable Interventional

A System of Safety (SOS)

NCT03104504
View directory record Official record
Conditions
Suicide
Interventions
Suicide Risk Screening, Safety Planning, Care transition facilitation, A Lean Implementation Strategy
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
12 Years and older
Enrollment
493,756 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2023
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 11, 2024 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Phase 2Phase 3 Interventional

NRX-101 for Bipolar Depression With Subacute Suicidal Ideation

NCT03395392
View directory record Official record
Conditions
Bipolar Depression, Suicidal Ideation and Behavior
Interventions
NRX-101, Lurasidone HCl
Drug
Lead sponsor
NeuroRx, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
14
States / cities
Culver City, California • Miami Lakes, Florida • Atlanta, Georgia + 10 more
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Jul 21, 2026, 5:27 PM EDT
Recruiting Not applicable Interventional

Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD

NCT07238192
View directory record Official record
Conditions
Posttraumatic Stress Disorder (PTSD), Suicidal Ideation, Suicide Attempt
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Enrolling by invitation No phase listed Observational

Youth Depression and Suicide Research Network

NCT04572321
View directory record Official record
Conditions
Depression, Suicide, Suicidal Ideation, Suicide, Attempted, Depressive Disorder, Depressive Symptoms, Depressive Episode, Depression and Suicide, Depression, Teen, Depression, Anxiety
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 20 Years
Enrollment
5,000 participants
Timeline
2020 – 2032
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Active, not recruiting Not applicable Interventional

Improving Care, Accelerating Recovery and Education

NCT06233747
View directory record Official record
Conditions
Mental Health Disorder, Suicide Attempt, Suicidal Ideation, Emergency Psychiatric
Interventions
Improving Care, Accelerating Recovery & Education (ICARE)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
12 Years to 17 Years
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Recruiting Not applicable Interventional

Refinements of Functional Communication Training

NCT04045600
View directory record Official record
Conditions
Aggression, Self-injurious Behavior
Interventions
Trad FCT, Mult FCT, Mult FCT + Stimulus Fading
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
3 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Somerset, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 16, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Not applicable Interventional

Expanding Interventions for Automatically Maintained SIB

NCT06739616
View directory record Official record
Conditions
Self-Injurious Behavior, Problem Behavior, Intellectual Disability, Autism Spectrum Disorder, Restricted Behavior
Interventions
AUTOSIB across time, AUTOSIB diminished reinforcement
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
2 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Randolph, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Jul 21, 2026, 5:27 PM EDT
Terminated Not applicable Interventional

Network Health Intervention for Adolescents Leaving Acute Psychiatric Care

NCT05340296
View directory record Official record
Conditions
Suicide, Attempted
Interventions
Acute Youth Connect
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
12 Years to 18 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Veterans Coping Long-term With Active Suicide

NCT01894841
View directory record Official record
Conditions
Suicide
Interventions
Coping Long Term with Active Suicide (CLASP), Safety Assessment and Follow Up Evaluation
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Feb 9, 2020 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Phase 2 Interventional Results available

Memantine in Body Focused Repetitive Behaviors

NCT04792645
View directory record Official record
Conditions
Trichotillomania (Hair-Pulling Disorder), Dermatillomania
Interventions
Placebo, Memantine
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 21, 2026, 5:27 PM EDT
Withdrawn Phase 2Phase 3 Interventional

Trial of Kuvan in Lesch-Nyhan Disease

NCT00935753
View directory record Official record
Conditions
Behavioral Manifestations of Lesch-Nyhan Disease
Interventions
sapropterin
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
4 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2019 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Digital Narrative Bibliotherapy as a Scalable Intervention for Suicidal Thoughts

NCT05351645
View directory record Official record
Conditions
Suicidal Ideation
Interventions
Treatment
Behavioral
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
864 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Developing an Intervention to Promote Lethal Means Safety in Suicidal Adolescents

NCT05423483
View directory record Official record
Conditions
Suicide
Interventions
Safe Home Text Message Reminders
Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
12 Years to 100 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 2, 2025 · Synced Jul 21, 2026, 5:27 PM EDT
Not yet recruiting Not applicable Interventional

A Just-in-time Adaptive Intervention for Suicide Safety Planning in Adolescents

NCT07348666
View directory record Official record
Conditions
Suicide, Mental Health Disorder, Anhedonia
Interventions
ViraSafe: Treatment pushes, BRITE
Behavioral
Lead sponsor
Ksana Health
Industry
Eligibility
13 Years to 24 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Eugene, Oregon • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 1, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Not yet recruiting Not applicable Interventional

Task-Shifting Adapted IPT-A for Youth Suicide Prevention

NCT07383831
View directory record Official record
Conditions
Suicidal Ideation, Depressive Symptoms, Adolescent Mental Health
Interventions
Adapted Brief Interpersonal Psychotherapy for Adolescents (IPT-A LAZOS), Usual Community Center Services
Behavioral · Other
Lead sponsor
Boston College
Other
Eligibility
12 Years to 17 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 21, 2026, 5:27 PM EDT
Completed Not applicable Interventional

Supplementing Brief Psychotherapy With a Mobile App

NCT05867316
View directory record Official record
Conditions
Suicide and Self-harm, Emotion Regulation
Interventions
Unified Protocol
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Jul 21, 2026, 5:27 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Executive Dysfunction and Suicide in Psychiatric Outpatients and Inpatients

NCT01043432
View directory record Official record
Conditions
Traumatic Brain Injury, Suicidality
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
133 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 11, 2015 · Synced Jul 21, 2026, 5:27 PM EDT