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ClinicalTrials.gov public records Last synced Oct 6, 2026, 9:36 AM EDT

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Showing 145–168 of 923 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Self-injury Clear all
Active, not recruiting Not applicable Interventional

Crisis Response Planning for Military Personnel

NCT05795764
View directory record Official record
Conditions
Suicidal, Suicide Threat, Suicidal Ideation
Interventions
Crisis Response Planning, Treatment as Usual
Behavioral
Lead sponsor
United States Naval Medical Center, San Diego
Federal
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional Results available

Primary Care Intervention to Reduce Prescription Opioid Overdoses

NCT02464410
View directory record Official record
Conditions
Pain, Drug Overdose, Opioid Use Disorders
Interventions
Motivational intervention, Psycho-educational control, Long-term opioid therapy informed consent
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 6, 2026, 9:36 AM EDT
Terminated Phase 2Phase 3 Interventional Accepts healthy volunteers

A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic

NCT05144685
View directory record Official record
Conditions
Suicide, Attempted, Suicidal Ideation
Interventions
OTX-202, OTX-000, Treatment as Usual
Device · Behavioral
Lead sponsor
Oui Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
356 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
6
States / cities
Denver, Colorado • New Haven, Connecticut • Omaha, Nebraska + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2025 · Synced Oct 6, 2026, 9:36 AM EDT
Enrolling by invitation Not applicable Interventional

Implementing A Secure Firearm Storage Program in Illinois Health Centers in Partnership With AllianceChicago and the Illinois Primary Health Care Association (COMMUNITY ASPIRE)

NCT06886776
View directory record Official record
Conditions
Suicide
Interventions
Implementation package (training and facilitation)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
Not listed
Enrollment
1,086 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 6, 2026, 9:36 AM EDT
Active, not recruiting Not applicable Interventional

Manage Emotions to Reduce Aggression (MERA)

NCT04793776
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Aggression, Emotion Regulation
Interventions
Manage Emotions to Reduce Aggression, Present Centered Psychotherapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 64 Years
Enrollment
233 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Tampa, Florida • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 6, 2026, 9:36 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Biological Triggers of Depression in Pregnancy

NCT02566980
View directory record Official record
Conditions
Depression and Suicide, Mood Disorders, Other Perinatal Conditions
Interventions
Not listed
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older · Female only
Enrollment
209 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
3
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 28, 2018 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional Results available

Comprehensive Adaptive Multisite Prevention of University Student Suicide

NCT04707066
View directory record Official record
Conditions
Suicide
Interventions
Treatment As Usual (TAU), Collaborative Assessment and Management of Suicidality (CAMS) - Phase 1, Dialectical Behavior Therapy (DBT) - Phase 2, Maintenance/Monitoring - Phase 2, Collaborative Assessment and Management of Suicidality (CAMS) - Phase 2
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 25 Years
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
4
States / cities
Reno, Nevada • New Brunswick, New Jersey • Durham, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2026 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Better Together Physician Coaching to Mitigate Burnout Amongst Clinicians

NCT05635448
View directory record Official record
Conditions
Burnout, Professional, Self Compassion, Flourishing, Imposter Syndrome, Moral Injury, Loneliness
Interventions
Better Together Physician Coaching Program, No intervention - waitlist control
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 6, 2026, 9:36 AM EDT
Not listed Not applicable Interventional

Suicide in Urban Natives: Detection and Networks to Combat Events

NCT03136094
View directory record Official record
Conditions
Suicide Prevention
Interventions
SBIRT+12, SBIRT+Usual Care
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 34 Years
Enrollment
698 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Jun 27, 2024 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional

Internet Self-Management for People With Intermittent Urinary Catheters

NCT02168465
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
teaching self-management of an intermittent catheter
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated May 7, 2015 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Tech4Rest Trial With Team Truck Drivers

NCT03108599
View directory record Official record
Conditions
Sleep, Sleep Disturbance, Sleep Disorder, Shift Work, Health Knowledge, Attitudes, Practice, Health Behavior, Fatigue, Vibration; Exposure
Interventions
Enhanced Cab, Fit4Sleep
Other · Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
21 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 25, 2024 · Synced Oct 6, 2026, 9:36 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Randomized Controlled Effectiveness Trial of VA S.A.V.E.

NCT06470867
View directory record Official record
Conditions
Suicide Prevention
Interventions
VA S.A.V.E., Control training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
701 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Phase 1 Interventional

Improving Quality-of-life and Depressive Symptoms of Combat Veterans Via Internet-based Intervention

NCT01231711
View directory record Official record
Conditions
Depression, Post-Traumatic Stress Disorder, Functional Status
Interventions
Vets Prevail
Behavioral
Lead sponsor
Prevail Health Solutions, LLC
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 1, 2010 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Phase 2 Interventional

A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide

NCT04669665
View directory record Official record
Conditions
Depressive Disorder, Major, Suicidal
Interventions
SLS-002, Placebo, Standard of care, Intranasal device
Drug · Other · Device
Lead sponsor
Seelos Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
164 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
21
States / cities
Orange, California • Panorama City, California • San Diego, California + 18 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2023 · Synced Oct 6, 2026, 9:36 AM EDT
Suspended Not applicable Interventional

Study to Evaluate the Safety and Efficacy of PEER Interactive Versus Treatment as Usual in Subjects With a Primary Diagnosis of Depression

NCT01794559
View directory record Official record
Conditions
Depressive Disorder
Interventions
PEER Interactive Report
Device
Lead sponsor
MYnd Analytics
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,922 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
2
States / cities
Bethesda, Maryland • Fort Belvoir, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 31, 2020 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Phase 1 Interventional

Improving Care Provided to Patients Treated in a Level 1 Trauma Center Post-suicide Attempt

NCT01355848
View directory record Official record
Conditions
Suicidal Ideas
Interventions
Brief Intervention for Suicidality
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
15 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 10, 2015 · Synced Oct 6, 2026, 9:36 AM EDT
Not listed Phase 3 Interventional

Repetitive Behavior Disorders in People With Severe Mental Retardation

NCT00491478
View directory record Official record
Conditions
Mental Retardation, Stereotyped Behavior, Self-Injurious Behavior, Compulsive Behavior
Interventions
sertraline
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 55 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1992
U.S. locations
2
States / cities
Gainesville, Florida • Morganton, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 26, 2007 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional

Development of a Positive Psychology Intervention to Reduce Suicide Risk

NCT01398891
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Positive Psychology Exercises
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 5, 2013 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional Results available

A Self-Management Program for Completers of Trauma-Focused Therapy for PTSD

NCT03225859
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
Self-Management Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Oct 6, 2026, 9:36 AM EDT
Recruiting No phase listed Observational

Proximal Risk for Suicide in Adolescents

NCT06400810
View directory record Official record
Conditions
Suicide, Mental Health Issue
Interventions
Analog Devices Inc.
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
13 Years to 17 Years
Enrollment
144 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Oct 6, 2026, 9:36 AM EDT
Terminated Not applicable Interventional

A Brief Mind-Body Bridging Intervention for Suicidal Ideation

NCT03677882
View directory record Official record
Conditions
Suicidal Ideation, Mind Body Bridging
Interventions
Mind Body Bridging Group Session
Behavioral
Lead sponsor
VA Salt Lake City Health Care System
Federal
Eligibility
18 Years to 80 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 13, 2024 · Synced Oct 6, 2026, 9:36 AM EDT
Recruiting No phase listed Observational

Natural History of Depression, Bipolar Disorder and Suicide Risk

NCT06462196
View directory record Official record
Conditions
Behavioral Symptoms, Suicide, Self-Injurious Behavior, Sensory System Agents, Analgesics, Peripheral Nervous System Agents, Physiological Effects of Drugs, Anesthetics, Dissociative, Anesthetics, General, Anesthetics, Central Nervous System Depressants, Excitatory Amino Acid Antagonists, Excitatory Amino Acid Agents, Neurotransmitter Agents, Molecular Mechanisms of Pharmacological Action, Ketamine, Depression, Unipolar, Depressive Symptoms, Treatment Resistant Depression, Major Depressive Disorder, Depression, Bipolar
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years to 120 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional

Laughter Therapy Effects on Mood, Stress and Self-efficacy in People With Neurological Diseases.

NCT02750982
View directory record Official record
Conditions
Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Brain Injury, Huntington's Disease, Multiple Sclerosis, Parkinson's Disease, Stroke, Spinal Cord Injury
Interventions
Laughter Therapy
Other
Lead sponsor
Brown, Theodore R., M.D., MPH
Individual
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Kirkland, Washington
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Oct 6, 2026, 9:36 AM EDT
Completed Not applicable Interventional

Real-time Intervention for Suicide Risk Reduction

NCT05848089
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt
Interventions
Brief skills sessions plus EMI skills practice prompts, Ecological momentary assessment (EMA), Treatment as usual (TAU)
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 6, 2026, 9:36 AM EDT