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ClinicalTrials.gov public records Last synced Oct 25, 2026, 12:32 AM EDT

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Showing 1–24 of 53 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Seminal Fluid Clear all
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Discarded Laboratory Pathological Specimens and Media

NCT01219439
View directory record Official record
Conditions
Non-viable Oocytes, Extra Spermatozoa, Seminal Fluid, Granulosa Cells, Serum, Follicular Fluid, Conditioned IVF Media
Interventions
Not listed
Lead sponsor
Reproductive Medicine Associates of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
10,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2022
U.S. locations
1
States / cities
Basking Ridge, New Jersey
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 25, 2026, 12:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Residence Time of Biomarkers of Semen Exposure

NCT00984555
View directory record Official record
Conditions
Semen Exposure
Interventions
Not listed
Lead sponsor
CONRAD
Other
Eligibility
18 Years to 55 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
2
States / cities
Baltimore, Maryland • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 22, 2010 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Not applicable Interventional

A Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients

NCT00002050
View directory record Official record
Conditions
HIV Infections
Interventions
Thymopentin
Drug
Lead sponsor
Immunobiology Research Institute
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Annandale, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Not applicable Interventional

Double Blind Study of Thymopentin Effects on HIV-1 Infectivity of Blood Mononuclear Cells and Semen in HIV Infected Patients

NCT00002049
View directory record Official record
Conditions
HIV Infections
Interventions
Thymopentin
Drug
Lead sponsor
Immunobiology Research Institute
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Annandale, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 25, 2026, 12:32 AM EDT
Terminated Phase 2 Interventional

Effect of Omega 3 Fats on Sperm Quality and Sexual Function

NCT00406874
View directory record Official record
Conditions
Infertility
Interventions
omega 3 fats, folic acid
Drug
Lead sponsor
Reproductive Partners Medical Group
Other
Eligibility
35 Years to 55 Years · Male only
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007
U.S. locations
1
States / cities
Redondo Beach, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2013 · Synced Oct 25, 2026, 12:32 AM EDT
Completed No phase listed Observational

Determination of HIV-1 Production by the Prostate

NCT00001584
View directory record Official record
Conditions
HIV Infections
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 25, 2026, 12:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Biology of HIV Transmission

NCT00001092
View directory record Official record
Conditions
HIV Infections
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2008
U.S. locations
3
States / cities
Los Angeles, California • San Diego, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2015 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Phase 2 Interventional Results available

To Evaluate Sperm Parameters in Men With Secondary Hypogonadism Previously Treated With Topical Testosterone

NCT00706719
View directory record Official record
Conditions
Secondary Hypogonadism
Interventions
25 mg Androxal, Testim 1%
Drug
Lead sponsor
Repros Therapeutics Inc.
Industry
Eligibility
21 Years to 60 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
2
States / cities
New York, New York • Purchase, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2015 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Not applicable Interventional

Semen Analysis After Proton Therapy for Prostate Cancer

NCT01072513
View directory record Official record
Conditions
Prostate Cancer
Interventions
Semen analysis
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older · Male only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Phase 4 Interventional Results available

Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters

NCT03203681
View directory record Official record
Conditions
Hypogonadism, Male
Interventions
Natesto
Drug
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Phase 1Phase 2 Interventional Results available

A Study Evaluating the Effect of Botulinum Toxin Type A on Semen Quality in Patients With Benign Prostatic Hyperplasia

NCT00894517
View directory record Official record
Conditions
Benign Prostatic Hyperplasia
Interventions
Botulinum Toxin Type A, Placebo (saline)
Biological · Drug
Lead sponsor
Allergan
Industry
Eligibility
45 Years to 70 Years · Male only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 30, 2013 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Study in Healthy Males to Measure Darunavir and Etravirine in Blood, Seminal Fluid, and Rectal Tissue

NCT00855088
View directory record Official record
Conditions
HIV/AIDS, HIV Infections
Interventions
darunavir, Ritonavir, Etravirine
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 49 Years · Male only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 13, 2011 · Synced Oct 25, 2026, 12:32 AM EDT
Recruiting Phase 2 Interventional

A Clinical Trial Evaluating the Efficacy and Safety of Leflutrozole on Testicular Function

NCT06993155
View directory record Official record
Conditions
Semen Quality
Interventions
Leflutrozole, Dose 1, Leflutrozole, Dose 2, Leflutrozole, Dose 3, Placebo
Drug
Lead sponsor
ReproNovo Aps
Industry
Eligibility
18 Years to 49 Years · Male only
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
North Hollywood, California • Pomona, California • Garden City, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Pharmacokinetic Study of Avanfil in Healthy Young Male Subjects

NCT00914511
View directory record Official record
Conditions
Avanfil ADME, Semen Exposure, Sperm Function
Interventions
avanafil 200mg
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
18 Years and older · Male only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 7, 2011 · Synced Oct 25, 2026, 12:32 AM EDT
Completed No phase listed Observational

A Study of the Pre- and Post-operative Semen Analyses and Reproductive Hormone Levels of Men Undergoing Weight-reduction Surgery

NCT00596739
View directory record Official record
Conditions
Male Infertility
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 25, 2026, 12:32 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Male Fertility Program

NCT01467869
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Not listed
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1991 – 2040
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 25, 2026, 12:32 AM EDT
Terminated Phase 3 Interventional Results available

Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis

NCT00767338
View directory record Official record
Conditions
Pregnancy, Infertility
Interventions
Timed intercourse, Microsurgical varicocelectomy, Intrauterine insemination
Behavioral · Procedure
Lead sponsor
Yale University
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
9
States / cities
Aurora, Colorado • New Haven, Connecticut • Ann Arbor, Michigan + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2013 · Synced Oct 25, 2026, 12:32 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Prospective Study on Power Prenatal Vitamins for Males on YO Score At-home Sperm Test Results

NCT05951075
View directory record Official record
Conditions
Spermatogenesis and Semen Disorders, Infertility, Male
Interventions
Power Prenatal for Sperm
Dietary Supplement
Lead sponsor
The Bird and Be Co Inc
Industry
Eligibility
18 Years to 50 Years · Male only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Encino, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Oct 25, 2026, 12:32 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0

NCT02839447
View directory record Official record
Conditions
Male Infertility
Interventions
Diagnostic
Diagnostic Test
Lead sponsor
Aytu BioPharma, Inc.
Industry
Eligibility
21 Years to 45 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
6
States / cities
Miami, Florida • New Orleans, Louisiana • Rochester, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 8, 2024 · Synced Oct 25, 2026, 12:32 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

NCT00011713
View directory record Official record
Conditions
Infertility
Interventions
Completion questionnaires/providing biological samples
Other
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
18 Years to 55 Years
Enrollment
1,474 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2020 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Not applicable Interventional Results available

Home Semen Testing in Men Beginning Attempts to Conceive

NCT05503862
View directory record Official record
Conditions
Male Infertility
Interventions
YoSperm
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older · Male only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Oct 25, 2026, 12:32 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Assessing the Effect of Abstinence Period on Semen Parameters

NCT05701163
View directory record Official record
Conditions
Infertility, Male
Interventions
Abstinence followed by semen sample collection.
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
20 Years to 45 Years · Male only
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Oct 25, 2026, 12:32 AM EDT
Completed No phase listed Observational

Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent Primary Malignant Brain Tumors

NCT00499798
View directory record Official record
Conditions
Brain and Central Nervous System Tumors, Chemotherapeutic Agent Toxicity, Infertility
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 25, 2026, 12:32 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Study of Semen Characteristics After 9 Months of Daily Tadalafil 20 mg

NCT00382135
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
tadalafil, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older · Male only
Enrollment
282 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Oct 25, 2007 · Synced Oct 25, 2026, 12:32 AM EDT