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ClinicalTrials.gov public records Last synced Oct 2, 2026, 4:14 AM EDT

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Showing 49–72 of 91 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sensori-Neural Deafness Clear all
Recruiting Not applicable Interventional

Neural Prediction to Enhance Language

NCT05962359
View directory record Official record
Conditions
Bilateral Sensorineural Hearing Loss, Speech and Language Development Delay Due to Hearing Loss, Social Communication
Interventions
Parent-Implemented Communication Treatment
Behavioral
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
0 Months to 5 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Clear Speech on Listening Effort and Memory in Sentence Processing

NCT06053190
View directory record Official record
Conditions
Speech, Memory, Delayed, Sensorineural Hearing Loss
Interventions
Sentence stimulus, Speaking style
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Phase 1 Interventional Results available

Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss

NCT02038972
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Autologous Stem Cells
Genetic
Lead sponsor
James Baumgartner, MD
Other
Eligibility
6 Weeks to 6 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Recruiting Phase 1Phase 2 Interventional

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

NCT05788536
View directory record Official record
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Interventions
DB-OTO
Genetic
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Phase 1Phase 2 Interventional Results available

FX-322 in Sensorineural Hearing Loss

NCT03616223
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
FX-322, Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 14, 2022 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional

Auditory Nerve Test System During Vestibular Schwannoma Resection

NCT04241679
View directory record Official record
Conditions
Vestibular Schwannoma, Acoustic Neuroma, Sensorineural Hearing Loss, Asymmetric Sensorineural Hearing Loss, Cochlear Nerve Damage, Cochlear Nerve Deafness, Skull Base Neoplasms, Auditory; Nerve
Interventions
Auditory Nerve Test System
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Oct 2, 2026, 4:14 AM EDT
Recruiting Phase 3 Interventional

Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

NCT05821959
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
AAVAnc80-hOTOF via Akouos Delivery Device, AAVAnc80-hOTOF via Akouos Delivery Device and Precision Delivery Mechanism
Combination Product
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
Not listed
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
6
States / cities
San Francisco, California • Iowa City, Iowa • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Recruiting Not applicable Interventional

Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery

NCT06664710
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Cochlear Implantation
Interventions
iotaSOFT Insertion System with AIM, iotaSOFT Insertion System with AIM Control
Device
Lead sponsor
iotaMotion, Inc.
Industry
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 1, 2025 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aid Noise Reduction in Pediatric Users Pilot Study (Oticon Pilot Study)

NCT04469946
View directory record Official record
Conditions
Hearing Impairment, Sensorineural Hearing Loss, Bilateral
Interventions
Oticon OpenSound Navigator speech enhancement algorithm
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
6 Years to 12 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 2, 2026, 4:14 AM EDT
Completed No phase listed Observational

Genetic Analysis of Hereditary Disorders of Hearing and Balance

NCT00023049
View directory record Official record
Conditions
Sensorineural Hearing Loss, Hearing Disorder, Vestibular Disease
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
Up to 99 Years
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 22, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

CI532 - Early Experience Study

NCT02755935
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Cochlear Nucleus CI532
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Months and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Skokie, Illinois • Iowa City, Iowa • Ann Arbor, Michigan + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 2, 2026, 4:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Determine the Incidence of Long QT Amongst a Large Cohort of Subjects Diagnosed With Unilateral or Bilateral Sensorineural Hearing Loss.

NCT02082431
View directory record Official record
Conditions
Sensorineural Hearing Loss, Long QT Syndrome
Interventions
Not listed
Lead sponsor
Pediatrix
Other
Eligibility
1 Day to 90 Days
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
12
States / cities
Anchorage, Alaska • Phoenix, Arizona • Waterford, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 5, 2020 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Phase 2 Interventional

The Effects of Gevokizumab in Corticosteroid-resistant Subjects With Autoimmune Inner Ear Disease

NCT01950312
View directory record Official record
Conditions
Autoimmune Inner Ear Disease
Interventions
gevokizumab
Drug
Lead sponsor
XOMA (US) LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Feb 3, 2016 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Phase 2 Interventional Results available

FX-322 in Adults With Stable Sensorineural Hearing Loss

NCT04120116
View directory record Official record
Conditions
Sensorineural Hearing Loss, Noise Induced Hearing Loss, Sudden Sensorineural Hearing Loss
Interventions
FX-322 (One Dose), FX-322 (Two Doses), FX-322 (Four Doses), Placebo
Drug
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
16
States / cities
Fresno, California • Torrance, California • Colorado Springs, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 2, 2026, 4:14 AM EDT
Terminated Not applicable Interventional Results available

An Evidence Based Delivery Model of Care for Newly Implanted Adult CI Recipients

NCT03904420
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Clinical Education and Treatment Model, Traditional Model
Other
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
2
States / cities
Wichita Falls, Texas • Edmonds, Washington
Source: ClinicalTrials.gov public record
Updated Oct 29, 2020 · Synced Oct 2, 2026, 4:14 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Binaural Cue Sensitivity in Children and Adults With Combined Electric and Acoustic Stimulation

NCT07356128
View directory record Official record
Conditions
Bilateral Sensorineural Hearing Loss, Cochlear Implant, Hearing Preservation, Electric and Acoustic Simulation
Interventions
binaural processing over time, binaural processing over time for children and adults with normal hearing
Behavioral
Lead sponsor
Hearts for Hearing
Other
Eligibility
5 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Phase 3 Interventional Results available

Sudden Deafness Treatment Trial

NCT00097448
View directory record Official record
Conditions
Sudden Deafness
Interventions
prednisone, methylprednisolone sodium succinate
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
14
States / cities
Los Angeles, California • San Diego, California • Gainesville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2017 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

Benefits of Bimodal Streaming With MED-EL Cochlear Implants and Starkey Hearing Aids

NCT07028619
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Sensorineural Hearing Loss, Bilateral, Cochlear Implant Recipients, Asymmetric Hearing Loss
Interventions
Bimodal Streaming Configuration
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Meridian, Idaho
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System

NCT00678899
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Nucleus Hybrid L24
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2015 · Synced Oct 2, 2026, 4:14 AM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment

NCT02809118
View directory record Official record
Conditions
Hearing Loss, Idiopathic Sudden Sensorineural
Interventions
AM-111 0.4 mg/ml, AM-111 0.8 mg/ml, Placebo
Drug · Other
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
38
States / cities
Birmingham, Alabama • Escondido, California • Fresno, California + 34 more
Source: ClinicalTrials.gov public record
Updated Aug 7, 2020 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outcomes in Children With Pre-operative Residual Hearing

NCT03379870
View directory record Official record
Conditions
High Frequency Sensorineural Hearing Impairment, Hearing Disorders in Children
Interventions
Electric Acoustic Speech Processor: Electric-acoustic stimulation fitting, Electric Acoustic Speech Processor: Full-electric stimulation fitting
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
60 Months to 215 Months
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Phase 1 Interventional

A Study Of The Effects Of PF-04958242 In Subjects With Age-Related Hearing Loss

NCT01518920
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
PF-04958242, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
50 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
11
States / cities
Anaheim, California • New Haven, Connecticut • South Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2019 · Synced Oct 2, 2026, 4:14 AM EDT
Withdrawn Phase 2 Interventional

A Trial of LY3056480 in Patients With SNLH

NCT05061758
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
LY3056480
Drug
Lead sponsor
Audion Therapeutics BV
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
3
States / cities
Chicago, Illinois • New York, New York • Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 25, 2022 · Synced Oct 2, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Listening Effort on Sentence Processing and Memory (Study 1)

NCT05584514
View directory record Official record
Conditions
Sentence Stimulus, Auditory Noise
Interventions
Sentence Stimulus, Auditory Noise
Other
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 90 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 18, 2023 · Synced Oct 2, 2026, 4:14 AM EDT