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Showing 25–48 of 90 matching trials from the live ClinicalTrials.gov search.
Conditions
Sensorineural Hearing Loss, Bilateral Hearing Loss, Cochlear Implantation, Hearing Disorders, Hearing Disorders and Deafness, Inner Ear Disorders, Hearing Impairment
Interventions
IotaSoft Robotic Insertion System, Manual Cochlear Implant Insertion
Device · Procedure
Lead sponsor
AdventHealth
Other
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Kissimmee, Florida
Conditions
Sensorineural Hearing Loss
Interventions
Extended Wear Hearing Aid
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Shenandoah, Texas
Conditions
Sensorineural Hearing Loss, Hearing Disorder, Vestibular Disease
Interventions
Not listed
Lead sponsor
National Institute on Deafness and Other Communication Disorders (NIDCD)
NIH
Eligibility
Up to 99 Years
Enrollment
335 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Head and Neck Cancer, Hearing Loss, Tinnitus, Dysphagia
Interventions
TIMELY REHAB
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2030
U.S. locations
3
States / cities
Durham, North Carolina • Portland, Oregon • Madison, Wisconsin
Conditions
Sensorineural Hearing Loss, Low-Frequency Residual Hearing
Interventions
CI632 Slim Modiolar Electrode
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years to 69 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
4
States / cities
Worcester, Massachusetts • Kansas City, Missouri • Cleveland, Ohio
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outcomes in Children With Pre-operative Residual Hearing

NCT03379870
Conditions
High Frequency Sensorineural Hearing Impairment, Hearing Disorders in Children
Interventions
Electric Acoustic Speech Processor: Electric-acoustic stimulation fitting, Electric Acoustic Speech Processor: Full-electric stimulation fitting
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
60 Months to 215 Months
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

CI532 - Early Experience Study

NCT02755935
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Cochlear Nucleus CI532
Device
Lead sponsor
Cochlear
Industry
Eligibility
12 Months and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Skokie, Illinois • Iowa City, Iowa • Ann Arbor, Michigan + 3 more
Conditions
Sensorineural Hearing Loss, Bilateral Hearing Loss
Interventions
CI632D, CI632
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Englewood, Colorado • Iowa City, Iowa • Cleveland, Ohio
Conditions
Hearing Loss, Sensorineural, Cochlear Implantation
Interventions
iotaSOFT Insertion System with AIM, iotaSOFT Insertion System with AIM Control
Device
Lead sponsor
iotaMotion, Inc.
Industry
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Alport Syndrome
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
0 Years to 99 Years
Enrollment
655 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Completed Not applicable Interventional Results available

Evaluation of the Nucleus Hybrid™ L24 Cochlear Implant System

NCT00678899
Conditions
Sensorineural Hearing Loss
Interventions
Nucleus Hybrid L24
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
New York, New York
Conditions
Presbycusis, Hearing Loss, Sensorineural, Noise Induced Hearing Loss, Sudden Hearing Loss
Interventions
FX-322, placebo
Drug · Other
Lead sponsor
Frequency Therapeutics
Industry
Eligibility
66 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
5
States / cities
Sarasota, Florida • Omaha, Nebraska • Amherst, New York + 2 more
Conditions
Sensorineural Hearing Loss
Interventions
Digital noise reduction
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 85 Years
Enrollment
288 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
2
States / cities
Bay Pines, Florida • Mountain Home, Tennessee
Conditions
Hearing Loss, Sensorineural Hearing Loss, Noise-Induced Hearing Loss
Interventions
HPN-07, NAC, Placebo
Drug
Lead sponsor
Otologic Pharmaceutics, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Raleigh, North Carolina
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF), Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene, Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) Genes
Interventions
Not listed
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Up to 7 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Phoenix, Arizona • Columbus, Ohio
Conditions
Hearing Loss
Interventions
Vibrant Soundbridge
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
11
States / cities
Los Angeles, California • San Jose, California • Miami, Florida + 8 more
Conditions
Sensorineural Hearing Loss
Interventions
Hybrid SRW cochlear implant
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Des Moines, Iowa
Conditions
Cochlear Implants, Sensory-Neural Hearing Loss, Balance Disorder
Interventions
Gross motor and developmental balance testing
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
12 Months to 71 Months
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Sensorineural Hearing Loss
Interventions
PIPE-505, Placebo
Drug
Lead sponsor
Contineum Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
8
States / cities
Torrance, California • Boca Raton, Florida • New Albany, Indiana + 5 more
Conditions
Sensorineural Hearing Loss, Autoimmune Inner Ear Disease
Interventions
Anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
13 Years to 75 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New Hyde Park, New York
Conditions
Hearing Loss, Sensorineural
Interventions
PF-04958242, Placebo
Drug
Lead sponsor
Biogen
Industry
Eligibility
50 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
11
States / cities
Anaheim, California • New Haven, Connecticut • South Miami, Florida + 2 more
Conditions
Hearing Loss, Sudden
Interventions
anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Hyde Park, New York
Enrolling by invitation No phase listed Observational

Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy

NCT06696456
Conditions
Otoferlin Gene-mediated Hearing Loss
Interventions
Not listed
Lead sponsor
Akouos, Inc.
Industry
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
3
States / cities
Iowa City, Iowa • Boston, Massachusetts • Philadelphia, Pennsylvania
Conditions
Bilateral Sensorineural Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
American Cochlear Implant Alliance
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
19
States / cities
Los Angeles, California • Englewood, Colorado • Miami, Florida + 16 more