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ClinicalTrials.gov public records Last synced Oct 11, 2026, 1:59 AM EDT

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Showing 49–58 of 58 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sepsis, Severe Sepsis and Septic Shock Clear all
Not listed No phase listed Observational

Pharmacogenomic Biomarker Study for Recombinant Human Activated Protein C Treatment in Severe Sepsis

NCT01486524
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
Not listed
Lead sponsor
Sirius Genomics Inc.
Industry
Eligibility
18 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
4
States / cities
Atlanta, Georgia • Baltimore, Maryland • Boston, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 6, 2011 · Synced Oct 11, 2026, 1:59 AM EDT
Completed Phase 2 Interventional Results available

GR270773 In The Treatment Of Suspected Or Confirmed Gram-Negative Severe Sepsis In Adults

NCT00089986
View directory record Official record
Conditions
Sepsis
Interventions
Intravenous GR270773- Phospholipid Emulsion, Placebo
Drug · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
1,415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
132
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 110 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Oct 11, 2026, 1:59 AM EDT
Completed Not applicable Interventional Results available

Preemptive Resuscitation for Eradication of Septic Shock

NCT01449721
View directory record Official record
Conditions
Sepsis, Severe Sepsis
Interventions
Intravenous fluid
Drug
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
5
States / cities
Newark, Delaware • Boston, Massachusetts • Detroit, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Oct 11, 2026, 1:59 AM EDT
Not listed No phase listed Observational

Echocardiography in Septic Shock

NCT02135796
View directory record Official record
Conditions
Septic Shock, Severe Sepsis
Interventions
Echocardiography
Other
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
13 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2019
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Oct 11, 2026, 1:59 AM EDT
Completed No phase listed Observational

IMproved PREdiction of Severe Sepsis in the Emergency Department

NCT01392508
View directory record Official record
Conditions
Systemic Inflammatory Response Syndrome (SIRS), Sepsis, Severe Sepsis, Septic Shock
Interventions
Not listed
Lead sponsor
Axis Shield Diagnostics Ltd
Industry
Eligibility
18 Years and older
Enrollment
759 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Oct 11, 2026, 1:59 AM EDT
Completed No phase listed Observational

Mitochondrial DNA as a Biomarker of Sepsis Severity

NCT03077672
View directory record Official record
Conditions
Sepsis Syndrome, Sepsis, Severe Sepsis, Septic Shock, Infection
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
1,304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 11, 2026, 1:59 AM EDT
Completed No phase listed Observational

Procalcitonin Monitoring Sepsis Study

NCT01523717
View directory record Official record
Conditions
Severe Sepsis, Septic Shock
Interventions
Not listed
Lead sponsor
Brahms AG
Industry
Eligibility
18 Years and older
Enrollment
858 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
13
States / cities
Sacramento, California • Chicago, Illinois • Boston, Massachusetts + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 11, 2026, 1:59 AM EDT
Completed Phase 3 Interventional

ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis

NCT00334828
View directory record Official record
Conditions
Severe Sepsis
Interventions
eritoran tetrasodium, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2006
U.S. locations
69
States / cities
Birmingham, Alabama • Mobile, Alabama • Mesa, Arizona + 66 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2017 · Synced Oct 11, 2026, 1:59 AM EDT
Not listed Not applicable Interventional

De-resuscitation Informed by Ultrasound for Patients With Sepsis

NCT04921319
View directory record Official record
Conditions
Sepsis, Septic Shock, Sepsis, Severe, Volume Overload
Interventions
VExUS score
Diagnostic Test
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Oct 11, 2026, 1:59 AM EDT
Not listed No phase listed Observational

Electronic Application of a Severe Sepsis Screening Tool and Management Bundle

NCT01724463
View directory record Official record
Conditions
Systemic Inflammatory Response Syndrome (SIRS), Sepsis, Severe Sepsis, Septic Shock
Interventions
Severe Sepsis Management Bundle
Other
Lead sponsor
University of Tennessee
Other
Eligibility
1 Month to 18 Years
Enrollment
30,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 31, 2015 · Synced Oct 11, 2026, 1:59 AM EDT