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ClinicalTrials.gov public records Last synced Oct 3, 2026, 9:30 PM EDT

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Showing 25–46 of 46 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Severe Burns Clear all
Completed Not applicable Interventional

Effects of a Community Based Exercise Program in Adults With Severe Burns

NCT01184547
View directory record Official record
Conditions
Burn Injury, Psychosocial Problem, Quality of Life
Interventions
Combex, Standard of Care
Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 6, 2020 · Synced Oct 3, 2026, 9:30 PM EDT
Completed No phase listed Observational

Low Dose Vitamin C in Burns >20% Compared to Previous Studies With High Dose Vitamin C

NCT05612867
View directory record Official record
Conditions
Burns, Ascorbic Acid Deficiency, Burn Shock, Burn Degree Second, Burn Degree Third, Fluid and Electrolyte Imbalance
Interventions
Vitamin C
Dietary Supplement
Lead sponsor
Arrowhead Regional Medical Center
Other
Eligibility
Not listed
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Colton, California
Source: ClinicalTrials.gov public record
Updated Nov 10, 2022 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 1 Interventional

Effect of Music Therapy on Families of Burn Patients

NCT00824681
View directory record Official record
Conditions
Burns
Interventions
Sound Of Family Together (S.O.F.T.) Music Program, Non-Therapy Related Activities (NTRA)
Behavioral · Other
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
6 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 23, 2010 · Synced Oct 3, 2026, 9:30 PM EDT
Completed Not applicable Interventional

Total Energy Expenditure, Protein Kinetics, and Body Composition in Recovering Burn Children.

NCT01544868
View directory record Official record
Conditions
Energy Expenditure in Burn Children, Protein Turnover in Burn Children
Interventions
Use of Stable Isotope to Measure Energy Expenditure and Protein Turnover
Other
Lead sponsor
Shriners Hospitals for Children
Other
Eligibility
2 Years to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 20, 2014 · Synced Oct 3, 2026, 9:30 PM EDT
Withdrawn No phase listed Observational

Glutamine Enriched Total Parenteral Feeding and Proline Metabolism in Severely Burned Patients

NCT00217035
View directory record Official record
Conditions
Burns
Interventions
TPN or TPN enriched with glutamine
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 3, 2026, 9:30 PM EDT
Withdrawn Not applicable Interventional

Microcirculatory Assessment in Patients With Trauma and Severe Burns

NCT01922960
View directory record Official record
Conditions
Burns, Trauma
Interventions
micro-imaging
Other
Lead sponsor
University of South Alabama
Other
Eligibility
19 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 29, 2017 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 2 Interventional Results available

Vitamin D and n-3 Polyunsaturated Fatty Acids (PUFAs) to Prevent Chronic Pain Following Major Thermal Burn Injury

NCT03313076
View directory record Official record
Conditions
Chronic Pain Following Thermal Burn Injury
Interventions
Omega-3 fatty acids (fish oil), Vitamin D3 (cholecalciferol), Vitamin D3 (cholecalciferol) placebo, Omega-3 fatty acid placebo
Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 3, 2026, 9:30 PM EDT
Recruiting Phase 4 Interventional

Pharmacokinetic Analysis of Cefiderocol in Patients With Acute Burn Injuries

NCT07465432
View directory record Official record
Conditions
Drug Clearance After Severe Burn Injury
Interventions
Cefiderocol
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 12, 2026 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 4 Interventional

Acute and Long-Term Outcome Investigations of Fenofibrate on Severely Burned Patients

NCT01574131
View directory record Official record
Conditions
Second or Third Degree Burns
Interventions
Fenofibrate, Sugar Pill
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
4 Years to 20 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2019 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 2Phase 3 Interventional

Bone Disease in Severely Burned Children

NCT00591162
View directory record Official record
Conditions
Burn
Interventions
Tetracycline, Duel Energy X-Ray Absorptiometry (DEXA), Bone Biopsy
Drug · Radiation · Procedure
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
5 Years to 18 Years
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2008
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 6, 2014 · Synced Oct 3, 2026, 9:30 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of Mitochondrial Dysfunction in Severe Burn and Trauma Patients

NCT01812941
View directory record Official record
Conditions
Burns, Trauma
Interventions
trauma: blood collection, healthy volunteers: blood collection, Burn: blood collection
Other
Lead sponsor
University of South Alabama
Other
Eligibility
19 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2021
U.S. locations
1
States / cities
Mobile, Alabama
Source: ClinicalTrials.gov public record
Updated May 28, 2021 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 2 Interventional Results available

Study of Tolerability and Efficacy of BVS857 in Severe Burn Subjects

NCT02074995
View directory record Official record
Conditions
Hypercatabolic Status Related to Severe Burn
Interventions
BVS857, placebo
Biological · Other
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Oct 3, 2026, 9:30 PM EDT
Completed Phase 4 Interventional

Oliceridine in Patients With Acute Burn Injuries

NCT05465226
View directory record Official record
Conditions
Acute Pain, Burns, Adverse Drug Event, Respiratory Depression, Nausea and Vomiting, Postoperative
Interventions
Oliceridine, Historical opioid use
Drug
Lead sponsor
University of Tennessee
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 26, 2023 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 2Phase 3 Interventional

Propranolol in Severely Burned Children

NCT01957449
View directory record Official record
Conditions
Burn
Interventions
Propranolol, Placebo
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 18 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
4
States / cities
Sacramento, California • Boston, Massachusetts • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Oct 3, 2026, 9:30 PM EDT
Active, not recruiting Not applicable Interventional

Assessment of Safety and Effectiveness of NovoSorb® BTM in Severe Burns

NCT04090424
View directory record Official record
Conditions
Burns
Interventions
NovoSorb BTM, Standard of Care
Device · Procedure
Lead sponsor
PolyNovo Biomaterials Pty Ltd.
Industry
Eligibility
18 Years to 75 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
23
States / cities
Phoenix, Arizona • Los Angeles, California • Sacramento, California + 19 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 3, 2026, 9:30 PM EDT
Withdrawn Phase 3 Interventional

Efficacy of Coenzyme Q10 Supplementation on Multi-Organ Dysfunction in Severely Burned Patients

NCT03968640
View directory record Official record
Conditions
Multiple Organ Failure
Interventions
CoQ10, Placebo
Dietary Supplement
Lead sponsor
American Burn Association
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 20, 2023 · Synced Oct 3, 2026, 9:30 PM EDT
Withdrawn No phase listed Observational

Proline Metabolism in Severely Burned Patients: Effect of Modulated Parenteral Feeding

NCT00216983
View directory record Official record
Conditions
Burns
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 13, 2017 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Phase 2Phase 3 Interventional

Assessment of the Treatment of Severely Burned With Anabolic Agents on Clinical Outcomes, Recovery and Rehabilitation

NCT00675714
View directory record Official record
Conditions
Burns
Interventions
Stable Isotope Infusion Study, Collection of blood and tissues, Radiology testing: Dual-energy X-ray absorptiometry (DEXA), ultrasound, MRI, Humatrope, Ketoconazole, Oxandrolone, Propranolol, Oxandrolone and propranolol combined, Humatrope and propranolol combined, Placebo, Exercise--Hospital supervised intensive exercise program, Home exercise program
Procedure · Drug · Behavioral
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
Up to 80 Years
Enrollment
1,126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2019
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 29, 2019 · Synced Oct 3, 2026, 9:30 PM EDT
Terminated Not applicable Interventional

Continuous Glucose Monitoring (POC) in the ICU

NCT00464386
View directory record Official record
Conditions
Burns, Trauma
Interventions
Continuous Glucose Monitoring
Device
Lead sponsor
United States Army Institute of Surgical Research
Federal
Eligibility
18 Years to 72 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 2, 2016 · Synced Oct 3, 2026, 9:30 PM EDT
Completed No phase listed Observational

Antimicrobial Resistance of Bacteria in Burn Patients

NCT00794742
View directory record Official record
Conditions
Burns
Interventions
Not listed
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Oct 3, 2026, 9:30 PM EDT
Completed Phase 1Phase 2 Interventional

Evaluation of Safety and Efficacy of realSKIN® (Skin Xenotransplant) for Complete Closure of Severe Burn Wounds

NCT03695939
View directory record Official record
Conditions
Deep Full-thickness Burn Injury (Disorder)
Interventions
realSKIN (skin xenotransplant), Human Cadaver Allograft
Biological
Lead sponsor
XenoTherapeutics, Inc.
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Augusta, Georgia • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2024 · Synced Oct 3, 2026, 9:30 PM EDT
Withdrawn Phase 2 Interventional

Vitamin C for Severe Thermal Injuries

NCT01587261
View directory record Official record
Conditions
Severe Thermal Injury, Greater Than 20% TBSA
Interventions
Vitamin C, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Oct 3, 2026, 9:30 PM EDT