- Conditions
- Severe Periodontitis, Acute Inflammatory Response
- Interventions
- Customized acrylic mouthguard
- Other
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 69 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2023
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
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Showing 1–7
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- Conditions
- Generalized Moderate Chronic Periodontitis, Generalized Severe Chronic Periodontitis, Periodontal Diseases
- Interventions
- Scaling and root planing, Er:YAG Laser, Hand instruments
- Procedure · Device
- Lead sponsor
- Columbia University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 29 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2019
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Periodontal Diseases
- Interventions
- MIST (minimally invasive surgical therapy)
- Device
- Lead sponsor
- McGuire Institute
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 54 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2018 – 2020
- U.S. locations
- 1
- States / cities
- Nashville, Tennessee
- Conditions
- Periodontal Disease
- Interventions
- ST266, Saline (0.9% NaCl)
- Biological · Drug
- Lead sponsor
- Noveome Biotherapeutics, formerly Stemnion
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 151 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2017
- U.S. locations
- 6
- States / cities
- Birmingham, Alabama • Indianapolis, Indiana • Cambridge, Massachusetts + 3 more
- Conditions
- Periodontitis Chronic Generalized Severe, Periodontitis Chronic Generalized Moderate
- Interventions
- leukocyte platelet rich fibrin (L-PRF), Scaling and Root Planing
- Biological · Procedure
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2022
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Severe Periodontitis
- Interventions
- Valacyclovir group, Control group
- Drug · Other
- Lead sponsor
- University of California, San Francisco
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 40 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- San Francisco, California
- Conditions
- Tooth Loss, Tooth Diseases, Tooth Fracture, Tooth Injuries, Periodontal Bone Loss, Periodontitis, Peri-Implantitis, Tooth Decay
- Interventions
- Not listed
- Lead sponsor
- Verdugo, Fernando, DDS
- Individual
- Eligibility
- 18 Years and older
- Enrollment
- 34 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Los Angeles, California