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Showing 1–24 of 49 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sex, Unsafe Clear all
Completed Not applicable Interventional Accepts healthy volunteers

MyLife MyStyle Evaluation Project

NCT01640392
View directory record Official record
Conditions
Unsafe Sex
Interventions
MyLife MyStyle group-level intervention
Behavioral
Lead sponsor
Los Angeles County Department of Public Health
Government
Eligibility
18 Years to 29 Years · Male only
Enrollment
528 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

No Excuses/Sin Buscar Excusas Intervention to Reduce Latino Men's HIV Risks

NCT00690690
View directory record Official record
Conditions
HIV Infections
Interventions
Video (group-delivered video-based intervention), HCT
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 49 Years · Male only
Enrollment
370 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 8, 2010 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intervention for Substance Use and Sexual Risk Behavior in Homeless Youth

NCT03735784
View directory record Official record
Conditions
Substance Use, Unprotected Sex
Interventions
AWARE
Behavioral
Lead sponsor
RAND
Other
Eligibility
18 Years to 25 Years
Enrollment
276 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
3
States / cities
Hollywood, California • Los Angeles, California • Venice Beach, California
Source: ClinicalTrials.gov public record
Updated Jun 20, 2021 · Synced Sep 11, 2026, 2:09 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Individual and Contextual Factors That Influence Sexual Decisions

NCT03224416
View directory record Official record
Conditions
Binge Drinking, Unsafe Sex, HIV/AIDS, Sexually Transmitted Diseases
Interventions
Alcohol Administration, Placebo Alcohol Administration, No Alcohol Administration
Other
Lead sponsor
Brown University
Other
Eligibility
21 Years to 35 Years · Male only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational

Quick Start of Highly Effective Contraception

NCT02076217
View directory record Official record
Conditions
IUD, Contraceptive Implant, Contraception, Birth Control, Emergency Contraception
Interventions
Copper T-380 IUD, LNG IUD, Contraceptive implant Nexplanon, Depo-Provera
Drug · Device
Lead sponsor
University of Utah
Other
Eligibility
15 Years to 45 Years · Female only
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Proyecto SOL: A Risk Reduction Intervention for Hispanic Men Who Have Sex With Men (MSM)

NCT00690976
View directory record Official record
Conditions
HIV Infections
Interventions
Proyecto SOL, HCT
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 49 Years · Male only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Mar 10, 2010 · Synced Sep 11, 2026, 2:09 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating a Digital Intervention to Improve Adolescent Condom Use and Communication

NCT06878755
View directory record Official record
Conditions
Condomless Sex, Sexual Assault
Interventions
Promoting Assertive Communication among Teens (PACT), Healthy Minds
Other
Lead sponsor
North Carolina Agriculture & Technical State University
Other
Eligibility
14 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Reducing Unsafe Alcohol Use in HIV-Positive Individuals

NCT00371969
View directory record Official record
Conditions
Alcohol Abuse
Interventions
Enhanced Motivational Interview, Standard Motivational Interview or viewing DVD
Behavioral
Lead sponsor
Research Foundation for Mental Hygiene, Inc.
Other
Eligibility
18 Years to 65 Years
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 29, 2015 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Evaluation of Pulse: A Mobile Health App and Teen Pregnancy Prevention Program

NCT04043130
View directory record Official record
Conditions
Unprotected Sex, Contraceptive Usage
Interventions
Pulse
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
18 Years to 20 Years · Female only
Enrollment
2,317 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 15, 2020 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional

An Evaluation of Re:MIX: a Teen Pregnancy Prevention Program With Young Parents as Peer Educators, EngenderHealth

NCT03114410
View directory record Official record
Conditions
Sexual Behavior, Unprotected Sex
Interventions
Re:MIX, a multi-layer comprehensive teen pregnancy prevention intervention aimed at reducing pregnancy and STIs among youth ages 13-17
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
12 Years to 18 Years
Enrollment
621 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2020 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Familias Unidas: Preventing Drug Abuse and HIV in Hispanic First Offenders

NCT01257022
View directory record Official record
Conditions
Substance Use, Unsafe Sexual Behavior
Interventions
Familias Unidas
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years to 17 Years
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 4, 2014 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protecting Our Future Generation: Promotion of Protective Sexual Health Practices Among Native American Youth and Young Adults Through an Assets-based Self-care Intervention

NCT03895320
View directory record Official record
Conditions
Sexual Behavior, Unprotected Sex, Gonorrhea, Chlamydia, Trichomonas, Sexually Transmitted Diseases, Adolescent Behavior, Self Evaluation
Interventions
Sexual Health Risk Assessment, Sexual Health Score, Sexual Health Messaging, Water SSB Quiz, Water SSB Score, Water SSB Messaging, STI Screening
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years to 26 Years
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Whiteriver, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 22, 2024 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Moon and Sun Brothers: A Community Prevention Intervention (Hermanos de Luna y Sol)

NCT07475702
View directory record Official record
Conditions
Help-Seeking Behavior, Pre-exposure Prophylaxis Use, Condomless Sex, Risky Health Behavior
Interventions
Moon and Sun Brothers: A Community Prevention Intervention
Behavioral
Lead sponsor
San Francisco State University
Other
Eligibility
18 Years and older
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
San Francisco, California • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Copper T380A IUD vs. Oral Levonorgestrel for Emergency Contraception

NCT00966771
View directory record Official record
Conditions
Pregnancy
Interventions
Copper T380 IUD, Oral levonorgestrel
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 30 Years · Female only
Enrollment
548 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Salt Lake City, Utah • West Valley City, Utah
Source: ClinicalTrials.gov public record
Updated Feb 5, 2017 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional

HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence

NCT01907126
View directory record Official record
Conditions
Unsafe Sex, Physical Violence, Sexual Assault, Sexual Abuse
Interventions
Nutrition Program (NP), Women's Prison CoOp (WPC)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
Framingham, Massachusetts • Cranston, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Sep 11, 2026, 2:09 AM EDT
Not listed Not applicable Interventional

Evaluating the Many Ways of Being Program

NCT05801601
View directory record Official record
Conditions
Sexual Behavior, Unprotected Sex
Interventions
Many Ways of Being, an innovative sexual health promotion program focused on addressing rigid gender norms and promoting healthy relationships, A career readiness program
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
15 Years to 19 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Familias Unidas: Preventing Substance Abuse in Hispanic Youth

NCT01038206
View directory record Official record
Conditions
Prevention, Family Function, Substance Use, Sexual Behavior
Interventions
Familias Unidas
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
12 Years and older
Enrollment
746 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Results available

Brief Interventions in the Emergency Department for Alcohol and HIV/Sexual Risk

NCT01351389
View directory record Official record
Conditions
Alcohol Consumption, Unsafe Sex
Interventions
Brief Motivational Intervention (BMI), Brief Advice
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
3
States / cities
Pawtucket, Rhode Island • Providence, Rhode Island • Warwick, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Positive Choice: Prevention for Positive Health

NCT00447707
View directory record Official record
Conditions
HIV Infections, Sexual Risk Behavior, Substance Use Risks
Interventions
Positive Choice
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years and older
Enrollment
497 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2006
U.S. locations
5
States / cities
Oakland, California • San Francisco, California • San Leandro, California
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Couple-Based Relationship Strengthening HIV Intervention for Young Parents

NCT01643005
View directory record Official record
Conditions
HIV
Interventions
Relationship Strengthening HIV Prevention Intervention, Parenting Program Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
14 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 25, 2020 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of the SafeSpace App Intervention

NCT06043596
View directory record Official record
Conditions
Health Behavior, Health Care Utilization, Unprotected Sex, Sexually Transmitted Infections
Interventions
SafeSpace Sexual Health, SafeSpace General Health
Behavioral
Lead sponsor
Child Trends
Other
Eligibility
14 Years to 18 Years · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Sep 11, 2026, 2:09 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Education and Employment Support for HIV Prevention in Young Adults (ENSPIRE)

NCT06096324
View directory record Official record
Conditions
Economic Hardship, Condomless Sex, Utilization, Health Care
Interventions
Job announcements plus HIV prevention text messages, educational sessions, economic resources, and mentoring., Job announcements
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 24 Years
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MI With Text Messaging to Reduce Sexual Risk and Hazardous Drinking Among MSM

NCT03755661
View directory record Official record
Conditions
Alcohol; Harmful Use, Sex, Unsafe
Interventions
MI&TXT4MSM
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
21 Years to 50 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 5, 2021 · Synced Sep 11, 2026, 2:09 AM EDT
Completed Not applicable Interventional

Cognitive Processing Intervention for Trauma, HIV/STI Risks, and Substance Use Among Native Women

NCT01849029
View directory record Official record
Conditions
Post Traumatic Stress Disorders, Unsafe Sex, Substance Use Disorders
Interventions
Cognitive Processing Therapy-Cognitive
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Toppenish, Washington
Source: ClinicalTrials.gov public record
Updated Aug 21, 2017 · Synced Sep 11, 2026, 2:09 AM EDT