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ClinicalTrials.gov public records Last synced Oct 19, 2026, 6:24 AM EDT

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Showing 73–96 of 110 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sex Differences Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Neural and Hormonal Influences on Sex Differences in Risk for AUD

NCT04929288
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Alcohol
Drug
Lead sponsor
Jessica Weafer
Other
Eligibility
21 Years to 26 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Not applicable Interventional Results available

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

NCT04448327
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
active tVNS, Sham tVNS
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 65 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sex Differences in E-cig Perception: Study 1

NCT05432830
View directory record Official record
Conditions
Nicotine Addiction, E-Cig Use, Cigarette Smoking, Sex Differences
Interventions
E-liquid Flavor 1, E-liquid Flavor 2, E-liquid Flavor 3
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 44 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Withdrawn Phase 3 Interventional

Pain Assessment and Quality of Life in Back Pain Patients: Role of Milnacipran

NCT01221740
View directory record Official record
Conditions
Back Pain
Interventions
Savella
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 19, 2026, 6:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Pain Perception Between Males and Females Following Laparoscopic Cholecystectomy

NCT00575276
View directory record Official record
Conditions
Cholecystitis, Acute, Cholecystitis, Chronic
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 8, 2012 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Specialized Centers of Research (SCOR)on Sex Differences - Kyphosis Study

NCT01766674
View directory record Official record
Conditions
Kyphosis
Interventions
Kyphosis spinal strengthening exercises
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 19, 2026, 6:24 AM EDT
Completed No phase listed Observational

Evaluation of Genetic Markers as Explanations for the Observed Differences in Disease Progression in HIV+ Youth

NCT00107029
View directory record Official record
Conditions
HIV Infection
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
Not listed
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
10
States / cities
Los Angeles, California • Washington D.C., District of Columbia • Fort Lauderdale, Florida + 7 more
Source: ClinicalTrials.gov public record
Updated Feb 28, 2017 · Synced Oct 19, 2026, 6:24 AM EDT
Completed No phase listed Observational

Gender and Neural Substrates of Stress and Craving

NCT00756925
View directory record Official record
Conditions
Cocaine Dependence
Interventions
Acthrel
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 7, 2018 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Brain Blood Flow Responses to Stress: Sex Differences

NCT06253702
View directory record Official record
Conditions
Cerebrovascular Disorders
Interventions
Indomethacin, Placebo, Orilissa, Testosterone gel, Anastrozole, Estradiol
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder

NCT06426303
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Naltrexone
Drug
Lead sponsor
Milky Kohno
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Sex Differences in E-Cigarette Perception

NCT07398976
View directory record Official record
Conditions
Nicotine Dependence, E-cigarette Use
Interventions
Nicotine Level 1 (0mg/ml), Nicotine Level 2 (36mg/ml), Nicotine Level 3 (59mg/ml)
Other
Lead sponsor
Yale University
Other
Eligibility
21 Years to 44 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Completed No phase listed Observational

Pharmacokinetic Evaluation of Changes in Nevirapine AUC Due to Differences in Weight

NCT01335360
View directory record Official record
Conditions
HIV Infection
Interventions
Nevirapine
Drug
Lead sponsor
Western University of Health Sciences
Other
Eligibility
18 Years to 50 Years · Male only
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 19, 2026, 6:24 AM EDT
Not yet recruiting Early Phase 1 Interventional Accepts healthy volunteers

Human Cerebrovascular Blood Flow and Sex Differences in Metabolic Syndrome

NCT07218653
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Indomethacin, Placebo, MRI
Drug · Diagnostic Test
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 45 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Adolescent Changes in Brain and Behavior in Boys and Girls With ADHD

NCT05927506
View directory record Official record
Conditions
ADHD, Attention Deficit Hyperactivity Disorder
Interventions
Other
Behavioral
Lead sponsor
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Other
Eligibility
12 Years to 17 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Alcohol and Gender Effects on Stress Circuit Function

NCT00226694
View directory record Official record
Conditions
Alcoholism, Stress, Alcohol Dependence
Interventions
Citalopram, Placebo
Drug · Other
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years to 65 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2012
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Oct 19, 2026, 6:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gender Differences of Neuroanatomical and Neurophysiological Correlates of Risk-proneness in Early Adolescents

NCT03534375
View directory record Official record
Conditions
Gender, Early Adolescent Behavior
Interventions
The study is an observational cross sectional study
Other
Lead sponsor
Texas Tech University
Other
Eligibility
10 Years to 12 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2021 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sex Differences in Attentional Bias in Marijuana-dependent Individuals

NCT01179425
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Cognitive stressor
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 14, 2011 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Sex-related Differences in Sympathetic Vascular Transduction in the Setting of Hypoxemia

NCT05256069
View directory record Official record
Conditions
Vasodilation, Hypoxia
Interventions
Propranolol Pill, Placebo
Drug
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years to 45 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Oct 19, 2026, 6:24 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Imaging Sex Differences in Smoking-Induced Pulmonary Inflammation

NCT03721822
View directory record Official record
Conditions
Smoking, Cigarette, Smoking E-cigarette, Healthy Volunteer
Interventions
[18F]NOS
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Phase 1 Interventional Results available

The Women's Recovery Group Study: Stage I Trial

NCT00230100
View directory record Official record
Conditions
Alcohol-Related Disorders, Substance-Related Disorders
Interventions
The Women's Recovery Group, mixed-gender Group Drug Counseling
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Oct 19, 2026, 6:24 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Sex Differences in the Vascular Effects of E-cigarette Use

NCT06159608
View directory record Official record
Conditions
E-cigarette Use
Interventions
Local heating + L-NAME (NG-nitro-L-arginine methyl ester; nitric oxide synthase inhibitor), Chronic estrogen exposure
Drug · Other
Lead sponsor
Anna Stanhewicz, PhD
Other
Eligibility
18 Years to 24 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Oct 19, 2026, 6:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HYPEROXIA Responses and ROS

NCT05958303
View directory record Official record
Conditions
Cerebrovascular Disorders
Interventions
Antioxidant Cocktail, Placebo
Dietary Supplement · Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

Gender Related Differences in the Acute Effects of Delta-9-Tetrahydrocannabinol in Healthy Humans: Sub-Study II

NCT04704271
View directory record Official record
Conditions
Cannabis
Interventions
Inhaled THC, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 19, 2026, 6:24 AM EDT
Terminated Not applicable Interventional

Therapeutic Targeting of Sex Differences in Pediatric Brain Tumor Glycolysis

NCT03591861
View directory record Official record
Conditions
Pediatric Brain Tumor
Interventions
Ketogenic diet, BCNU
Procedure · Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Up to 21 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 12, 2022 · Synced Oct 19, 2026, 6:24 AM EDT