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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sexual Dysfunction, Physiological Clear all
Completed Phase 1 Interventional

Vardenafil ODT (Orally Disintegrating Tablet) - Nifedipine Interaction Study

NCT01348880
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Vardenafil ODT, (Staxyn, BAY38-9456), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
65 Years to 80 Years · Male only
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
2
States / cities
Miami, Florida • Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 18, 2014 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Botox Injection for Treatment of Vaginismus

NCT01352546
View directory record Official record
Conditions
Vaginismus
Interventions
BOTOX
Biological
Lead sponsor
Plastic Surgery Professional Association
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Aug 6, 2017 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Not applicable Interventional

Pelvic Physical Therapy for Sexual Dysfunction in Gynecologic Oncology Survivors

NCT05242770
View directory record Official record
Conditions
Gynecologic Cancer, Sexual Dysfunction
Interventions
Control Arm, Physical Therapy Arm, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-QLQ-C30), Female Sexual Function Index (FSFI), Exit Interview
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 22, 2026 · Synced Sep 15, 2026, 7:52 PM EDT
Not listed Phase 4 Interventional

Clinical Efficacy of Changing the InterStim® Parameters in Patients With Interstitial Cystitis/Painful Bladder Syndrome

NCT01312259
View directory record Official record
Conditions
Painful Bladder Syndrome, Interstitial Cystitis, Pelvic Floor; Insufficiency, Bowel Dysfunction, Sexual Dysfunction, Pelvic Floor; Incompetency
Interventions
Changing the Interstim parameter of '' Frequency" in patients with Interstitial Cystitis
Other
Lead sponsor
Pelvic and Sexual Health Institute
Other
Eligibility
18 Years to 70 Years · Female only
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 28, 2014 · Synced Sep 15, 2026, 7:52 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Postcoital Sponge on Self-Reported Vaginal Health Parameters

NCT06530186
View directory record Official record
Conditions
Vaginal Infection, Vaginal Discharge, Vaginosis, Sexual Dysfunction
Interventions
LiviWell Postcoital Vaginal Insert
Device
Lead sponsor
Atlantic Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Mountain Lakes, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 1 Interventional

Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of Mild to Moderate ED

NCT02398370
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
Biological
Lead sponsor
Melissa Marchand
Other
Eligibility
40 Years to 70 Years · Male only
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Coral Springs, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2015 · Synced Sep 15, 2026, 7:52 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Transvaginal Low-level Laser Therapy to Improve Pelvic Pain and Sexual Function in Patients with Endometriosis.

NCT05540353
View directory record Official record
Conditions
Endometriosis, Dyspareunia, Pelvic Pain
Interventions
Transvaginal photobiomodulation, Sham therapy
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
6
States / cities
Washington D.C., District of Columbia • Mitchellville, Maryland • Rockville, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2025 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 3 Interventional Results available

The Vaginal Health Trial

NCT02516202
View directory record Official record
Conditions
Atrophy of Vagina, Menopause, Dyspareunia (Female)
Interventions
Vagifem, Replens, Placebo tablet, Placebo gel
Drug · Device · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
302 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Minneapolis, Minnesota • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 11, 2018 · Synced Sep 15, 2026, 7:52 PM EDT
Not yet recruiting Not applicable Interventional

Improving Sexual Health in Gynecological Cancer Patients

NCT07144566
View directory record Official record
Conditions
Gynaecologic Cancer
Interventions
Nurse Led Sexual Health Clinical Program Intervention
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 26, 2025 · Synced Sep 15, 2026, 7:52 PM EDT
Completed No phase listed Observational

The Women's Urology Center/WISH Database Project

NCT00379002
View directory record Official record
Conditions
Interstitial Cystitis, Sexual Dysfunction, Pelvic Pain, Incontinence
Interventions
Not listed
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older · Female only
Enrollment
2,923 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 3, 2020 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Autologous Platelet-Rich Plasma for Erectile Dysfunction.

NCT04396795
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Autologous Platelet Rich Plasma, Saline solution
Drug · Other
Lead sponsor
University of Miami
Other
Eligibility
30 Years to 75 Years · Male only
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Sep 15, 2026, 7:52 PM EDT
Terminated Phase 4 Interventional

Does Vilazodone Help With Antidepressant-associated Sexual Dysfunction?

NCT01856127
View directory record Official record
Conditions
Sexual Dysfunction, Major Depressive Disorder
Interventions
Vilazodone, Sertraline
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
3
States / cities
Philadelphia, Pennsylvania • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 24, 2016 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treating Postmenopausal Dyspareunia Where it Hurts

NCT03240081
View directory record Official record
Conditions
Dyspareunia
Interventions
50mcg estradiol cream, 100mcg estradiol cream
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 21, 2023 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 3 Interventional

To Determine How Different Doses of Tadalafil Work on Getting and Keeping an Erection 26 or 36 Hours After Taking

NCT00547508
View directory record Official record
Conditions
Impotence
Interventions
tadalafil, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older · Male only
Enrollment
485 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 21, 2007 · Synced Sep 15, 2026, 7:52 PM EDT
Recruiting Not applicable Interventional

Efficacy of Low-intensity Shockwave vs Radial Wave for Treatment of Erectile Dysfunction and Pelvic Pain

NCT05868668
View directory record Official record
Conditions
Erectile Dysfunction Due to Arterial Insufficiency, Erectile Dysfunction, Erectile Dysfunction Due to Arterial Disease, Chronic Pelvic Pain Syndrome, Chronic Prostatitis, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Radiation Therapy
Interventions
Focused shockwave, Radial wave, Sham treatment
Device
Lead sponsor
The Cleveland Clinic
Other
Eligibility
40 Years and older · Male only
Enrollment
186 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 15, 2026, 7:52 PM EDT
Completed No phase listed Interventional Accepts healthy volunteers Results available

A Study to Measure the Degree and Effectiveness of the Various vSculpt Operating Modes

NCT02856490
View directory record Official record
Conditions
Sexual Dysfunction, Stress Incontinence
Interventions
vSculpt, InTone
Device
Lead sponsor
Joylux, Inc.
Other
Eligibility
48 Years to 60 Years · Female only
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

Pilot Trial Evaluating Stereotactic Body Radiotherapy With Integrated Boost for Clinically Localized Prostate Cancer (RAD 1203)

NCT01856855
View directory record Official record
Conditions
Prostate Cancer, Prostate Adenocarcinoma, Radiation Toxicity, Sexual Dysfunction
Interventions
Stereotactic Body Radiation Therapy with Integrated Boost
Radiation
Lead sponsor
John Fiveash, MD
Other
Eligibility
19 Years and older · Male only
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 11, 2023 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

A Study of Semen Characteristics After 9 Months of Daily Tadalafil 20 mg

NCT00382135
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
tadalafil, placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
45 Years and older · Male only
Enrollment
282 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bothell, Washington
Source: ClinicalTrials.gov public record
Updated Oct 24, 2007 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Mirabegron For Erectile Dysfunction

NCT02916693
View directory record Official record
Conditions
Erectile Dysfunction, Overactive Bladder, Urinary Incontinence
Interventions
Mirabegron
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 4, 2021 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 2 Interventional

POMx In the Treatment of Erectile Dysfunction

NCT01220206
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
Placebo, One POMx capsule daily, 2 POMx Capsules
Drug
Lead sponsor
POM Wonderful LLC
Industry
Eligibility
21 Years to 70 Years · Male only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Huntsville, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 4, 2012 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Not applicable Interventional Results available

A Mindfulness-based Intervention for Older Women With Low Sexual Desire

NCT03232801
View directory record Official record
Conditions
Hypoactive Sexual Desire Disorder, Sexual Dysfunction, Female Sexual Dysfunction
Interventions
mindfulness-based multicomponent intervention, general health education group
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older · Female only
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Not applicable Interventional

Erectile Dysfunction Study

NCT00873665
View directory record Official record
Conditions
Erectile Dysfunction
Interventions
aerobic exercise, wait-list control
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Male only
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2013 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Tadalafil in Preventing Erectile Dysfunction in Patients With Prostate Cancer Treated With Radiation Therapy

NCT00931528
View directory record Official record
Conditions
Prostate Cancer, Sexual Dysfunction
Interventions
Tadalafil, Placebo
Drug · Other
Lead sponsor
Radiation Therapy Oncology Group
Network
Eligibility
18 Years to 120 Years · Male only
Enrollment
242 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
183
States / cities
Birmingham, Alabama • Mobile, Alabama • Peoria, Arizona + 151 more
Source: ClinicalTrials.gov public record
Updated Feb 13, 2018 · Synced Sep 15, 2026, 7:52 PM EDT
Completed Phase 3 Interventional Results available

Efficacy and Safety of Linzagolix for the Treatment of Endometriosis-associated Pain.

NCT03992846
View directory record Official record
Conditions
Endometriosis
Interventions
75 mg linzagolix tablet, 200 mg linzagolix tablet, Add-back capsule (E2 1 mg / NETA 0.5 mg), Placebo tablet to match 75 mg linzagolix tablet, Placebo tablet to match 200 mg linzagolix tablet, Placebo capsule to match Add-back capsule
Drug
Lead sponsor
Kissei Pharmaceutical Co., Ltd.
Industry
Eligibility
18 Years to 49 Years · Female only
Enrollment
486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
22
States / cities
Birmingham, Alabama • Dothan, Alabama • Chiefland, Florida + 19 more
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Sep 15, 2026, 7:52 PM EDT