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Showing 1–24 of 141 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sexual Minorities Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Project Minority AIDS Prevention: Reaching Black and Hispanic MSM About PrEP and TasP Using Social Media

NCT03404531
View directory record Official record
Conditions
HIV Infections
Interventions
Social Media Messages Intervention Group, Website Only Group
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years and older · Male only
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

C2P - Phase III: MPowerment and Community Promise

NCT00381784
View directory record Official record
Conditions
HIV Infections
Interventions
Printed materials, Peer advocates
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
12 Years to 24 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
6
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced Sep 2, 2026, 4:41 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Prospective Evaluation of Self-Testing to Increase Screening (PRESTIS) Asian/Asian American Women Supplement

NCT06577220
View directory record Official record
Conditions
Cervical Cancer, Human Papillomavirus Infection
Interventions
Telephone Recall, Mailed HPV Self-Sampling Kit, Patient Navigation
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
30 Years to 65 Years · Female only
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults

NCT05847673
View directory record Official record
Conditions
Cigarette Smoking-Related Carcinoma
Interventions
Online Smoking Cessation Intervention, Questionnaire Administration, Health Promotion and Education
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
125 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 18, 2024 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Digital Wellbeing Project

NCT05061966
View directory record Official record
Conditions
Mental Health
Interventions
immi, Control
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
13 Years to 19 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Sep 2, 2026, 4:41 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

HIV Pre-Exposure Prophylaxis Among an Unrecognized Sexual Minority Population

NCT05815030
View directory record Official record
Conditions
Pre-Exposure Prophylaxis
Interventions
video informational/educational intervention
Other
Lead sponsor
The Alternative Sexualities Health Research Alliance
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Rio Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2025 · Synced Sep 2, 2026, 4:41 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Caregiver-Adolescent Dating Violence Prevention Intervention Pilot Trial

NCT07718022
View directory record Official record
Conditions
Adolescent Relationship Abuse, Sexual and Gender Minorities
Interventions
FLARE, Resource Guide
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years and older
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 9, 2026 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Sexual and Gender Minority Emerging Adults Eliciting Narratives

NCT05899218
View directory record Official record
Conditions
Mental Health Wellness 1, Sexual Orientation, Gender Identity
Interventions
Critical Narrative Development
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 24 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration

NCT03584932
View directory record Official record
Conditions
HIV/AIDS
Interventions
LINK2 Youth Services Navigation Intervention
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
16 Years to 25 Years · Male only
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers

NCT06644664
View directory record Official record
Conditions
Tobacco-Related Carcinoma
Interventions
Health Education, Interview, Smoking Cessation Intervention, Survey Administration, Text Message-Based Navigation Intervention
Behavioral · Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 35 Years
Enrollment
292 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 29, 2026 · Synced Sep 2, 2026, 4:41 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Family Acceptance Project Online (Pilot RCT)

NCT06839859
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Family Acceptance Project - Online
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Healthy Families Bright Futures Program

NCT06309134
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
Healthy Families Bright Futures Program
Behavioral
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
15 Years to 18 Years
Enrollment
122 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Pride Body Project

NCT03451513
View directory record Official record
Conditions
Eating Disorder, Body Image
Interventions
Pride Body Project, Media Advocacy
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 35 Years
Enrollment
453 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 29, 2023 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Phase 1 Interventional

Flexiquit+: Web Program to Promote Smoking Cessation in Sexual and Gender Minority Young Adult Smokers

NCT04194918
View directory record Official record
Conditions
Tobacco Use Disorder
Interventions
Computer-Assisted Smoking Cessation Intervention, Text Message, Handout, Questionnaire Administration, Quality-of-Life Assessment, Survey Administration
Behavioral · Other
Lead sponsor
Fred Hutchinson Cancer Center
Other
Eligibility
18 Years to 30 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults

NCT03751020
View directory record Official record
Conditions
Depression, Suicidality, Substance Abuse, HIV, Minority Stress
Interventions
Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 29 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
New Haven, Connecticut • Worcester, Massachusetts • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 27, 2020 · Synced Sep 2, 2026, 4:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Improving The Breast Cancer Care Delivery Model for Sex and Gender Minority Survivors, Intended for SGM Study

NCT06205394
View directory record Official record
Conditions
Breast Carcinoma
Interventions
Non-Interventional Study
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
Not listed
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 15, 2024 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening

NCT06100250
View directory record Official record
Conditions
Sexually Transmitted Diseases, Gonorrhea, Chlamydia, Syphilis, HIV
Interventions
Motivational interviewing and specimen self-collection
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

MySTYLE: Online Family-based HIV Prevention for Non-heterosexual Black Adolescent Males in the South

NCT03487796
View directory record Official record
Conditions
Hiv, Adolescent Behavior, Family Relations, Sexual Orientation
Interventions
MySTYLE, Waitlist Control
Behavioral · Other
Lead sponsor
Rhode Island Hospital
Other
Eligibility
14 Years to 20 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Dec 28, 2021 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Results available

SmokefreeSGM, A Text-based Smoking Cessation Feasibility Trial for Sexual and Gender Minority Groups

NCT05645354
View directory record Official record
Conditions
Smoking Cessation
Interventions
SmokefreeSGM, SmokefreeTXT
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth

NCT03709472
View directory record Official record
Conditions
Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation, Family Relations
Interventions
Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
11 Years to 18 Years
Enrollment
172 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Gamified, Social Media Inspired Personalized Normative Feedback Alcohol Intervention for Sexual Minority Women

NCT03884478
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol; Harmful Use
Interventions
Personalized Normative Feedback
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
21 Years to 55 Years · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Not applicable Interventional

Gene Expression Outcomes in Interventions for Substance Using HIV+ Minority Men

NCT03143205
View directory record Official record
Conditions
Human Immunodeficiency Virus Infection, Inflammation
Interventions
AWARENESS for Sexual Minorities, Writing tasks
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 21, 2024 · Synced Sep 2, 2026, 4:41 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Community Intervention Trial for Youth (CITY) Study

NCT00164580
View directory record Official record
Conditions
HIV Infections
Interventions
Community-Level Intervention
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
15 Years to 25 Years · Male only
Enrollment
12,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2004
U.S. locations
8
States / cities
Birmingham, Alabama • Los Angeles, California • San Francisco, California + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 26, 2012 · Synced Sep 2, 2026, 4:41 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

HIV Prevention and PrEP Intervention for SGM Adolescents and Parents: "Hey, Friend"

NCT04846946
View directory record Official record
Conditions
HIV Infections
Interventions
Hey, Friend
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
14 Years to 18 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 1, 2022 · Synced Sep 2, 2026, 4:41 AM EDT