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Showing 1–20 of 20 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sexual Minority Stress Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Proximal Effects of Alcohol on Same-Sex Intimate Partner Violence

NCT04625465
View directory record Official record
Conditions
Alcohol Consumption, Violence, Domestic, Stress, Psychological, Aggression
Interventions
CBT Text Messaging, Attention Control Text Messaging
Behavioral
Lead sponsor
Georgia State University
Other
Eligibility
21 Years and older
Enrollment
474 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Self-Compassion Practice on Stress Reactivity Among Sexual Minority Women

NCT05949060
View directory record Official record
Conditions
Stress Reaction, Sexuality, Compassion
Interventions
Compassion Intervention
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of a Multi-Level School Intervention for LGBTQ Youth

NCT04041414
View directory record Official record
Conditions
Sexual Minority Stress Experiences Among LGBTQ Youth
Interventions
Proud & Empowered!
Other
Lead sponsor
University of Southern California
Other
Eligibility
12 Years to 20 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
4
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Jul 21, 2026, 9:10 PM EDT
Recruiting Not applicable Interventional

A Comparative Effectiveness Study of PTSD Treatments Among Sexual and Gender Minority Populations

NCT06367764
View directory record Official record
Conditions
PTSD
Interventions
Cognitive Processing Therapy, STAIR Narrative Therapy
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
2
States / cities
Palo Alto, California • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Apr 23, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Results available

Project EQuIP: Empowering Queer Identities in Psychotherapy

NCT03721276
View directory record Official record
Conditions
Sexual Minority Stress
Interventions
EQuIP (Empowering Queer Identities in Psychotherapy)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

NCT04546061
View directory record Official record
Conditions
Substance Use, Mental Health
Interventions
Project Uplift
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Charlotte, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Trans Care: An Online Intervention to Reduce Symptoms of Gender Dysphoria

NCT05884307
View directory record Official record
Conditions
Gender Dysphoria
Interventions
Trans Care Web App
Other
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 21, 2026, 9:10 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Efficacy of a Multi-level School Intervention for LGBTQ Youth

NCT05541406
View directory record Official record
Conditions
Depression, Anxiety, Post Traumatic Stress Disorder, Coping Behavior, Sexual Minority Stress, Suicidality, Substance Use, Bullying, Harassment
Interventions
Proud & Empowered
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 20 Years
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
21
States / cities
El Monte, California • Glendale, California • Inglewood, California + 6 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Family Acceptance Project Online (Pilot RCT)

NCT06839859
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Family Acceptance Project - Online
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
14 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project QueST 2023: Queer Survivors of Trauma

NCT05569915
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Drinking Heavy
Interventions
Trauma Expressive Writing, Stigma Expressive Writing, Control
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Jul 21, 2026, 9:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Healthy Families Bright Futures Program

NCT06309134
View directory record Official record
Conditions
Alcohol Drinking, Violence in Adolescence
Interventions
Healthy Families Bright Futures Program
Behavioral
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
15 Years to 18 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 16, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Reducing Daily Stress Among Sexual and Gender Minorities

NCT05131360
View directory record Official record
Conditions
Social Discrimination, Sexual and Gender Minorities, Mindfulness
Interventions
Introduction Only, Purpose Only, Connection Only, Connection and Purpose, Awareness Only, Awareness and Purpose, Awareness, Purpose, and Connection, Awareness and Connection
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years to 29 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 22, 2021 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM

NCT05540652
View directory record Official record
Conditions
HIV, Minority Stress, Mental Health Wellness 1
Interventions
Mindfulness-Based Queer Resilience (MBQR)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 18, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Developing an Online Mindfulness-based Intervention to Reduce Minority Stress and HIV Risk Among Young Adult MSM - Aim 3

NCT05855655
View directory record Official record
Conditions
Hiv, Minority Stress, Mental Health Wellness 1
Interventions
Mindfulness-Based Queer Resilience (MBQR)
Behavioral
Lead sponsor
Brown University
Other
Eligibility
18 Years to 34 Years · Male only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Mental Health Experiences of Sexual and Gender Minorities Living With Cancer and Their Care Partners

NCT05866705
View directory record Official record
Conditions
Depression, Anxiety, Caregiver Burden, Stress, Chronic Illness
Interventions
Not listed
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
21 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 24, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk

NCT02929069
View directory record Official record
Conditions
HIV, Acquired Immunodeficiency Syndrome
Interventions
ESTEEM, CMHT, VCT
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
2
States / cities
New Haven, Connecticut • Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Jul 21, 2026, 9:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Affirmative Psychotherapy for Sexual Minority Women's Mental and Behavioral Health

NCT05509166
View directory record Official record
Conditions
Heavy Drinking, Mental Health Issue
Interventions
LGBTQ-affirmative Cognitive Behavioral Therapy, LGBTQ-affirmative Treatment-As-Usual
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
274 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 8, 2026 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Results available

Web-Based Cognitive Behavioral Stress Management for Latino Sexual Minority Men Living With HIV and Cancer

NCT03993054
View directory record Official record
Conditions
HIV/AIDS, Cancer
Interventions
Culturally-tailored cognitive behavioral stress management
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 1, 2025 · Synced Jul 21, 2026, 9:10 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Lakota Family Acceptance Project

NCT07326748
View directory record Official record
Conditions
LGBTQ, Racial Disparities, Family Relationships, Minority Stress, Depression, Anxiety, Drug Use, Teen Dating Violence, Sexual Risk Reduction
Interventions
Adapted Lakota Family Acceptance Program
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Pine Ridge, South Dakota • Rapid City, South Dakota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2026 · Synced Jul 21, 2026, 9:10 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults

NCT03751020
View directory record Official record
Conditions
Depression, Suicidality, Substance Abuse, HIV, Minority Stress
Interventions
Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 29 Years
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
New Haven, Connecticut • Worcester, Massachusetts • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 27, 2020 · Synced Jul 21, 2026, 9:10 PM EDT