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Showing 1–24 of 106 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sexual and Gender Minorities Clear all
Completed Not applicable Interventional

Randomized Controlled Trial of Project Body Neutrality

NCT06172452
View directory record Official record
Conditions
Depression, Eating Disorders, Body Image
Interventions
Project Body Neutrality SSI, Supportive Therapy SSI
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
13 Years to 17 Years
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of a Multi-Level School Intervention for LGBTQ Youth

NCT04041414
View directory record Official record
Conditions
Sexual Minority Stress Experiences Among LGBTQ Youth
Interventions
Proud & Empowered!
Other
Lead sponsor
University of Southern California
Other
Eligibility
12 Years to 20 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
4
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated Jul 27, 2021 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project PRIDE (Promoting Resilience In Discriminatory Environments)

NCT03528135
View directory record Official record
Conditions
Human Immunodeficiency Virus, Sexually Transmitted Infections, Anxiety, Depression, Substance Use Disorders
Interventions
Project PRIDE
Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 25 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated May 24, 2022 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Suicide Prevention for Sexual and Gender Minority Youth (Case Series)

NCT04757649
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention with Navigation Services
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
15 Years to 29 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 28, 2024 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mitigating Sexual Stigma Within Healthcare Interactions Improve Engagement of MSM in HIV Prevention

NCT04779736
View directory record Official record
Conditions
Human Immunodeficiency Virus, Stigma, Social, Patient Engagement
Interventions
A set of implementation strategies to reduce sexual stigma
Behavioral
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Results available

Project EQuIP: Empowering Queer Identities in Psychotherapy

NCT03721276
View directory record Official record
Conditions
Sexual Minority Stress
Interventions
EQuIP (Empowering Queer Identities in Psychotherapy)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 35 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Jun 10, 2026, 7:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

International Kink Health Study

NCT05318053
View directory record Official record
Conditions
Wounds and Injuries, Mental Health
Interventions
Not listed
Lead sponsor
The Alternative Sexualities Health Research Alliance
Other
Eligibility
18 Years and older
Enrollment
917 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rio Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 23, 2025 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

NCT04546061
View directory record Official record
Conditions
Substance Use, Mental Health
Interventions
Project Uplift
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Charlotte, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Supporting Trans Identities and Occupational Justice Through Narrative Informed Theatre: Supporting Trans Identities and Occupational Justice Through Narrative Informed Theatre

NCT04515654
View directory record Official record
Conditions
Transgenderism, Stigma, Social
Interventions
IDEAS (Identity Evolution and Sharing) Performance
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 16, 2020 · Synced Jun 10, 2026, 7:50 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Game-Based Intervention to Reduce Alcohol-Related Harms Among Sexual and Gender Minority Youth

NCT06215664
View directory record Official record
Conditions
Alcohol Problem, Harm Reduction, Alcohol-Related Harm
Interventions
Singularities Game, Food4Thought
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
14 Years to 18 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Jun 10, 2026, 7:50 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

PrEPsmart 2-1-1 Pilot

NCT06631365
View directory record Official record
Conditions
HIV-1-infection
Interventions
PrEPsmart mobile app, Truvada
Device · Drug
Lead sponsor
Public Health Foundation Enterprises, Inc.
Other
Eligibility
18 Years and older · Male only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Oct 7, 2024 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PrEP Affect Regulation Treatment Innovation

NCT04899024
View directory record Official record
Conditions
Medication Adherence, HIV Prevention, Stimulant Use
Interventions
PARTI, Attention-Control, Contingency Management for PrEP Adherence
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
18 Years and older · Male only
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
San Francisco, California • Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Results available

Zenyth: Motivational Interviewing-based Telehealth Intervention for Bacterial Sexually Transmitted Infection Screening

NCT06100250
View directory record Official record
Conditions
Sexually Transmitted Diseases, Gonorrhea, Chlamydia, Syphilis, HIV
Interventions
Motivational interviewing and specimen self-collection
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 30, 2025 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Gamified, Social Media Inspired Personalized Normative Feedback Alcohol Intervention for Sexual Minority Women

NCT03884478
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Abuse, Alcohol; Harmful Use
Interventions
Personalized Normative Feedback
Behavioral
Lead sponsor
Loyola Marymount University
Other
Eligibility
21 Years to 55 Years · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Preventing Drug Abuse Among Sexual Minority Youth

NCT03954535
View directory record Official record
Conditions
Substance Abuse
Interventions
Free2b, Attention-Placebo
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
15 Years to 17 Years
Enrollment
1,216 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Project QueST 2023: Queer Survivors of Trauma

NCT05569915
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Drinking Heavy
Interventions
Trauma Expressive Writing, Stigma Expressive Writing, Control
Behavioral
Lead sponsor
Syracuse University
Other
Eligibility
18 Years and older
Enrollment
131 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

PrEPTECH Phase 2 Study of a PrEP Telehealth Intervention

NCT04902820
View directory record Official record
Conditions
Pre-Exposure Prophylaxis, HIV, Telemedicine
Interventions
PrEPTECH website, Online PrEP resource list
Other
Lead sponsor
ETR Associates
Other
Eligibility
15 Years to 27 Years · Male only
Enrollment
229 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Scotts Valley, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2023 · Synced Jun 10, 2026, 7:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

SGM Evidenced-Based Mental Healthcare Implementation

NCT05890404
View directory record Official record
Conditions
CBT, LGBTQ
Interventions
LGBTQ-Affirmative CBT Training: Materials Only, LGBTQ-Affirmative CBT Training: Direct Training, LGBTQ-Affirmative CBT Training: Local Supervision
Behavioral
Lead sponsor
Yale University
Other
Eligibility
15 Years and older
Enrollment
1,410 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 4, 2025 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Suicide Prevention for Sexual and Gender Minority Youth (Open Trial)

NCT05087966
View directory record Official record
Conditions
Suicide
Interventions
Safety Planning Intervention with Navigation Services
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
15 Years to 29 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Results available

Web-Based Cognitive Behavioral Stress Management for Latino Sexual Minority Men Living With HIV and Cancer

NCT03993054
View directory record Official record
Conditions
HIV/AIDS, Cancer
Interventions
Culturally-tailored cognitive behavioral stress management
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older · Male only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 1, 2025 · Synced Jun 10, 2026, 7:50 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Parent-focused Intervention to Reduce HIV Risk in Gay and Bisexual Adolescents

NCT05852600
View directory record Official record
Conditions
Hiv, Sexual Health
Interventions
Parents and Adolescents Talking about Healthy Sexuality (PATHS), Lead with Love (LWL)
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
14 Years and older
Enrollment
393 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Jun 10, 2026, 7:50 AM EDT
Recruiting Phase 3 Interventional

Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents

NCT05766592
View directory record Official record
Conditions
Mental Health Issue, Parent-Child Relations
Interventions
LGBTQ-affirmative CBT, ABFT-SGM
Behavioral
Lead sponsor
Yale University
Other
Eligibility
20 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 12, 2026 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Project RESIST: Evaluating the Effects of Anti-smoking Inoculation Messages Among Young Adult Sexual Minority Women

NCT05499520
View directory record Official record
Conditions
Cigarette Smoking Behavior
Interventions
Culturally Tailored Anti-Smoking Messages
Other
Lead sponsor
Abramson Cancer Center at Penn Medicine
Other
Eligibility
18 Years to 30 Years
Enrollment
2,591 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Jun 10, 2026, 7:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

HPV Vaccine Intervention for Young Sexual Minority Men

NCT04032106
View directory record Official record
Conditions
Healthy Subject
Interventions
Best Practice, Informational Intervention, Questionnaire Administration, Text Message-Based Intervention
Other · Behavioral
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years to 25 Years · Male only
Enrollment
1,227 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
2
States / cities
Minneapolis, Minnesota • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Jun 10, 2026, 7:50 AM EDT