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Conditions: HIV
Interventions: Truvada, Gel lubricant; Drug · Device
Lead sponsor: Emory University; Other
Eligibility: 18 Years to 49 Years · Male only
Enrollment: 86 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Papillomavirus Infections
Interventions: 851B; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 240 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 22
States / cities: Colton, California • San Diego, California • Colorado Springs, Colorado + 19 more

Conditions: HIV Infections
Interventions: CD4 Antigens; Drug
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 1 Day to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 6
States / cities: San Francisco, California • Stanford, California • Chicago, Illinois + 2 more

Conditions: HIV Infection
Interventions: Not listed
Lead sponsor: National Cancer Institute (NCI); NIH
Eligibility: Not listed
Enrollment: 55 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: HIV Infections
Interventions: Virtual Reality, Health Promotion; Behavioral
Lead sponsor: Rhode Island Hospital; Other
Eligibility: 12 Years to 16 Years
Enrollment: 196 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2010
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: HIV, Acquired Immunodeficiency Syndrome
Interventions: ESTEEM, CMHT, VCT; Behavioral
Lead sponsor: Yale University; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 254 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 2
States / cities: New Haven, Connecticut • Miami, Florida

Conditions: Body Weight Changes, Human Immunodeficiency Virus, ART, Obesity, Minority Health, BMD, Metabolic Syndrome, Fasting
Interventions: DOR/3TC/TDF, DOR + FTC/TAF, BIC/FTC/TAF; Drug · Combination Product
Lead sponsor: Prism Health North Texas; Other
Eligibility: 18 Years and older · Female only
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: HIV Infections, Episodic Substance Use
Interventions: Adapted Personalized Cognitive Risk-reduction Counseling intervention (PCC), Standard HIV testing with information only; Behavioral
Lead sponsor: San Francisco Department of Public Health; Government
Eligibility: 18 Years and older · Male only
Enrollment: 385 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: HIV Prevention, Sexually Transmitted Diseases, Pre-Exposure Prophylaxis
Interventions: HOME Study intervention, Control; Behavioral
Lead sponsor: Public Health Foundation Enterprises, Inc.; Other
Eligibility: 18 Years to 35 Years · Male only
Enrollment: 104 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Substance Use Disorders, HIV Infections
Interventions: Virtual Reality Tool; Behavioral
Lead sponsor: Medical University of South Carolina; Other
Eligibility: 15 Years to 30 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Charleston, South Carolina

Conditions: HIV Infections, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depression, Substance Abuse
Interventions: Twinrix, Enhanced treatment as usual; Drug · Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 236 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose, Substance Abuse, Intravenous Drug Usage, Opiate Substitution Treatment, Sexually Transmitted Diseases
Interventions: Harm reduction kiosk; Behavioral
Lead sponsor: April M Young; Other
Eligibility: 18 Years and older
Enrollment: 752 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Lexington, Kentucky

Conditions: HIV Infections, Heart Disease
Interventions: Lovaza, Placebo; Drug
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years to 70 Years
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: HIV/AIDS
Interventions: Family-Based HIV prevention, Adolescent Only Health Promotion; Behavioral · Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 13 Years to 18 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: HIV/AIDS
Interventions: LINK2 Youth Services Navigation Intervention; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 16 Years to 25 Years · Male only
Enrollment: 106 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Infections, Papillomavirus
Interventions: Data collection; Other
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 15 Years to 25 Years · Female only
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: San Diego, California

Conditions: Antisocial Behavior, Psychopathology, Substance Use, HIV Infections
Interventions: Nurse Home Visiting; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 17 Years to 65 Years
Enrollment: 1,880 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Human Immunodeficiency Virus Exposure, Alcohol; Harmful Use
Interventions: Game Plan for PrEP, Attention-Matched Control Lifestyle Habits Videos; Behavioral
Lead sponsor: Brown University; Other
Eligibility: 18 Years and older · Male only
Enrollment: 73 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Contraceptive Usage, Opioid Dependence
Interventions: Treatment as usual, WHO contraception protocol, Incentives; Behavioral
Lead sponsor: University of Vermont; Other
Eligibility: 18 Years to 44 Years · Female only
Enrollment: 138 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2019
U.S. locations: 1
States / cities: Burlington, Vermont

Conditions: Substance Abuse, Substance Addiction, Substance Use Disorder (SUD), Substance Use (Drugs, Alcohol), Human Immunodeficiency Virus (HIV)
Interventions: The TLC Program; Behavioral
Lead sponsor: Illinois Institute of Technology; Other
Eligibility: 18 Years and older
Enrollment: 124 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chlamydia Trachomatis Infection, Neisseria Gonorrhoeae Infection, Mycoplasma Genitalium Infection
Interventions: cobas® liat CT/NG/MG nucleic acid test, Standard of Care (SOC): Clinician's Standard Practice; Diagnostic Test · Other
Lead sponsor: Hoffmann-La Roche; Industry
Eligibility: 18 Years and older
Enrollment: 331 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2025
U.S. locations: 4
States / cities: San Francisco, California • Hamilton Square, New Jersey • Perth Amboy, New Jersey + 1 more

Conditions: HIV Infections
Interventions: Focus Group, First Intervention Trial, Intervention Trial 2; Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 16 Years to 24 Years
Enrollment: 46 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 3
States / cities: Los Angeles, California • New York, New York • Philadelphia, Pennsylvania

Conditions: Substance Use, HIV Infections
Interventions: Couples Health Project; Behavioral
Lead sponsor: Hunter College of City University of New York; Other
Eligibility: 18 Years to 55 Years · Male only
Enrollment: 360 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2029
U.S. locations: 3
States / cities: Detroit, Michigan • New York, New York • Charlottesville, Virginia

Conditions: Sexually Transmitted Diseases, Substance-Related Disorders
Interventions: Partner-Specific IMB-based HIV risk reduction intervention, Healthy Lifestyle; Behavioral
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 15 Years to 18 Years
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Providence, Rhode Island

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PrEP, Lube, and the Rectal Mucosa in MSM at Risk of HIV

Efficacy of 851B Gel for Treating High-Risk Cervical Human Papillomavirus Infection in Women.

A Phase I Study of the Safety and Pharmacokinetics of Recombinant CD4 (rCD4) in Infants and Children Infected With or at Risk for HIV Infection

Long-Term Survival With HIV: Psychological and Behavioral Factors Associated With the Transition From Adolescence to Young Adulthood

Eliciting Affect in Teens in a Virtual World (Project AVATAR)

A Unified Intervention for Young Gay and Bisexual Men's Minority Stress, Mental Health, and HIV Risk

Doravirine and Weight Gain in Antiretroviral Naive

Reducing HIV Risk Among Episodic Substance Using Men Who Have Sex With Men (SUMSM)

HOME Study: a Combination Support Package to Increase Uptake of PrEP and HIV/STI Testing

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder

Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk

Pilot Placebo Controlled Study With Lovaza in Cardiovascular Disease

Project RAP: Family-based HIV Prevention in the Juvenile Drug Court

Youth Services Navigation Intervention for HIV+ Youth Being Released From or At-risk for Incarceration

Post-marketing Study to Assess the Safety of CERVARIX When Used in the United States and in Canada

Age-17 Follow-up of Home Visiting Intervention

Game Plan for PrEP

Improving Effective Contraceptive Use Among Opioid-maintained Women: Stage II

The Trans-Led Care Study

A Study of the Cobas® Liat CT/NG/MG Test Versus Current Standard Practice for Managing Participants at Increased Risk of Sexually Transmitted Infections

Integrated Treatment of Marijuana Abuse for HIV+ Youth

Couples Motivational Interviewing to Reduce Drug Use and HIV Risk in Vulnerable Male Couples

Partner-Specific HIV Risk Reduction Intervention for Drug-Using Adolescents