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ClinicalTrials.gov public records Last synced May 21, 2026, 7:36 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 528 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Shock Clear all
Recruiting Phase 3 Interventional
View directory record Official record
Conditions
Wounds and Injuries, Shock, Hemorrhagic
Interventions
LTOWB, Components
Biological
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
15 Years and older
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
13
States / cities
Birmingham, Alabama • Los Angeles, California • New Orleans, Louisiana + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2025 · Synced May 21, 2026, 7:36 PM EDT
Terminated Phase 1 Interventional
View directory record Official record
Conditions
Trauma, Critical Illness, Shock
Interventions
Glutamine
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 22, 2010 · Synced May 21, 2026, 7:36 PM EDT
Not listed Phase 3 Interventional Accepts healthy volunteers
View directory record Official record
Conditions
Kidney Stones
Interventions
LithoSpace Extracorporeal Shockwave Lithotripter
Device
Lead sponsor
Advance Shockwave Technology GmbH
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
2
States / cities
Garden City, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2011 · Synced May 21, 2026, 7:36 PM EDT
Not listed Phase 2 Interventional
View directory record Official record
Conditions
Shock, Hemorrhagic, Shock, Traumatic, Shock, Septic
Interventions
Polydatin Injectable
Drug
Lead sponsor
Neptunus Pharmaceuticals Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced May 21, 2026, 7:36 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Shock
Interventions
CareGuide™ device
Device
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 22, 2017 · Synced May 21, 2026, 7:36 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Sepsis, Systemic Inflammatory Response Syndrome
Interventions
Not listed
Lead sponsor
Immunexpress
Industry
Eligibility
18 Years to 95 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
3
States / cities
Los Angeles, California • Atlanta, Georgia • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced May 21, 2026, 7:36 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Sepsis, Shock
Interventions
Tissue oxygenation monitoring
Device
Lead sponsor
University of Michigan
Other
Eligibility
30 Days to 18 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 22, 2017 · Synced May 21, 2026, 7:36 PM EDT
Withdrawn Phase 2Phase 3 Interventional
View directory record Official record
Conditions
Shock, Hemorrhagic
Interventions
Plasma, Normal saline
Biological · Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 22, 2016 · Synced May 21, 2026, 7:36 PM EDT
Not yet recruiting Phase 1Phase 2 Interventional
View directory record Official record
Conditions
B-Acute Lymphoblastic Leukemia, CAR-T Cell Therapy, Cytokine Release Syndrome, Immune Effector Cell Associated Neurotoxicity Syndrome, Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome
Interventions
Anakinra (Kineret®)
Drug
Lead sponsor
Ann & Robert H Lurie Children's Hospital of Chicago
Other
Eligibility
1 Year to 25 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 14, 2025 · Synced May 21, 2026, 7:36 PM EDT
Not listed No phase listed Observational
View directory record Official record
Conditions
Streptococcal Sepsis, Invasive Group A Beta-Haemolytic Streptococcal Disease, Necrotizing Soft Tissue Infection, Infection, Bloodstream, Infection, Bacterial, Streptococcal Toxic Shock Syndrome
Interventions
Linezolid, Clindamycin
Drug
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
18 Years to 100 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced May 21, 2026, 7:36 PM EDT
Terminated Phase 3 Interventional Results available
View directory record Official record
Conditions
Hemorrhagic Shock
Interventions
Whole blood
Biological
Lead sponsor
Jason Sperry
Other
Eligibility
18 Years to 89 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 5, 2021 · Synced May 21, 2026, 7:36 PM EDT
Enrolling by invitation No phase listed Observational
View directory record Official record
Conditions
Severe Sepsis, Severe Sepsis Without Septic Shock
Interventions
Not listed
Lead sponsor
Beckman Coulter, Inc.
Industry
Eligibility
18 Years to 89 Years
Enrollment
40,000 participants
Timeline
2021 – 2026
U.S. locations
10
States / cities
Irvine, California • Augusta, Georgia • Indianapolis, Indiana + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced May 21, 2026, 7:36 PM EDT
Completed Phase 1Phase 2 Interventional Results available
View directory record Official record
Conditions
Septic Shock
Interventions
Acetyl-L-Carnitine
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced May 21, 2026, 7:36 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Septic Shock
Interventions
Esmolol
Drug
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Murray, Utah
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced May 21, 2026, 7:36 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Sepsis, Septic Shock, Severe Sepsis
Interventions
Severe Sepsis Prediction, Severe Sepsis Detection
Other
Lead sponsor
Dascena
Industry
Eligibility
18 Years and older
Enrollment
142 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2016
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced May 21, 2026, 7:36 PM EDT
Terminated No phase listed Observational
View directory record Official record
Conditions
Heart Failure, Cardiogenic Shock
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
1,089 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
7
States / cities
Aurora, Colorado • Minneapolis, Minnesota • St Louis, Missouri + 4 more
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced May 21, 2026, 7:36 PM EDT
Completed Not applicable Interventional
View directory record Official record
Conditions
Sepsis, Septic Shock, Emergencies
Interventions
Septic Shock Clinical Decision Support, Clinical Diagnosis Only
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
1,345 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced May 21, 2026, 7:36 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Sepsis, Infection, Septic Shock
Interventions
HBP lab test
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
1,055 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Sep 24, 2017 · Synced May 21, 2026, 7:36 PM EDT
Completed Phase 2 Interventional Results available
View directory record Official record
Conditions
Acute Pancreatitis, Systemic Inflammatory Response Syndrome
Interventions
CM-4620 Injectable Emulsion or CM-4620-IE, Placebo
Drug · Other
Lead sponsor
CalciMedica, Inc.
Industry
Eligibility
18 Years and older
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
27
States / cities
Long Beach, California • Los Angeles, California • Orange, California + 21 more
Source: ClinicalTrials.gov public record
Updated Oct 15, 2025 · Synced May 21, 2026, 7:36 PM EDT
Completed Phase 2 Interventional
View directory record Official record
Conditions
Sepsis, Shock, Septic, Sepsis Syndrome, Septicemia, Infection
Interventions
E5564
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2005
U.S. locations
17
States / cities
Mobile, Alabama • San Diego, California • Santa Barbara, California + 14 more
Source: ClinicalTrials.gov public record
Updated Dec 11, 2005 · Synced May 21, 2026, 7:36 PM EDT
Terminated Phase 4 Interventional Results available
View directory record Official record
Conditions
Septic Shock, Sepsis, Shock, Tachycardia, Arrhythmia
Interventions
Phenylephrine, Norepinephrine
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 12, 2018 · Synced May 21, 2026, 7:36 PM EDT
Not listed Not applicable Interventional
View directory record Official record
Conditions
Patients Who Are in Shock and Intubated in the Trauma Bay (TB)
Interventions
Limited Transthoracic Echocardiogram (LTTE, SonoSite Ultrasound), Usual care
Device · Other
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Apr 16, 2017 · Synced May 21, 2026, 7:36 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Shock
Interventions
USCOM
Device
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 23, 2014 · Synced May 21, 2026, 7:36 PM EDT
Completed No phase listed Observational
View directory record Official record
Conditions
Cardiogenic Shock, Acute Decompensated Heart Failure
Interventions
Impella 5.5
Device
Lead sponsor
Abiomed Inc.
Industry
Eligibility
18 Years and older
Enrollment
1,017 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
15
States / cities
Los Angeles, California • Orlando, Florida • Tampa, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced May 21, 2026, 7:36 PM EDT