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ClinicalTrials.gov public records Last synced Oct 11, 2026, 11:08 AM EDT

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Showing 25–48 of 103 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Shoulder Arthritis Osteoarthritis Clear all
Terminated Phase 1 Interventional

CAM Procedure With BMAC for Shoulder OA

NCT04826224
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Concentrated bone marrow aspirate administration after Comprehensive Arthroscopic Management (CAM) surgical procedure.
Biological
Lead sponsor
Shane A. Shapiro
Other
Eligibility
50 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Recruiting Not applicable Interventional

Rehabilitation Following Reverse Total Shoulder Arthroplasty

NCT03804853
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Rehabilitiation
Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
55 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
1
States / cities
Bloomington, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Withdrawn Not applicable Interventional

Subscapularis Repair During Reverse Total Shoulder Arthroplasty

NCT05341518
View directory record Official record
Conditions
Shoulder Osteoarthritis, Arthropathy Shoulder
Interventions
Subscapularis repair
Procedure
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 88 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Maywood, Illinois • Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 15, 2024 · Synced Oct 11, 2026, 11:08 AM EDT
Enrolling by invitation No phase listed Observational

Subscapularis-Sparing Total Shoulder Arthroplasty

NCT07410650
View directory record Official record
Conditions
Total Shoulder Arthroplasty
Interventions
Subscapularis-Sparing Total Shoulder Arthroplasty
Procedure
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 90 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Not listed Phase 2 Interventional

Autologous Adipose Tissue-Derived Mesenchymal Stem Cells (AdMSCs) for Osteoarthritis

NCT04448106
View directory record Official record
Conditions
Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis Shoulder
Interventions
Celltex- AdMSCs
Biological
Lead sponsor
Celltex Therapeutics Corporation
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Phase 3 Interventional Results available

Long-term Observational Study of Subjects From Tanezumab Studies Who Undergo a Total Knee, Hip or Shoulder Replacement

NCT02674386
View directory record Official record
Conditions
Osteoarthritis
Interventions
Investigational Medical Product (IMP) administered in parent study
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
154 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
51
States / cities
Birmingham, Alabama • Tucson, Arizona • Little Rock, Arkansas + 36 more
Source: ClinicalTrials.gov public record
Updated Jul 30, 2020 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Phase 4 Interventional Results available

Platelet-rich Plasma vs. Hyaluronic Acid for Glenohumeral Osteoarthritis

NCT02984228
View directory record Official record
Conditions
Osteoarthritis, Shoulder Pain
Interventions
PRP, Hyaluronic Acid, Ultrasound
Biological · Drug · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years to 100 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 11, 2026, 11:08 AM EDT
Terminated No phase listed Observational

Effect of Corticosteroid Injections on Blood Glucose

NCT05048264
View directory record Official record
Conditions
Diabetes Mellitus, Steroid Diabetes, Shoulder Osteoarthritis, Knee Osteoarthritis, Adhesive Capsulitis, Hip Osteoarthritis
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
40 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 11, 2026, 11:08 AM EDT
Recruiting Phase 1 Interventional

The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis

NCT04929951
View directory record Official record
Conditions
Osteoarthritis Shoulder, Shoulder Pain
Interventions
Micro Fragmented Adipose Tissue, Corticosteroid injection
Biological
Lead sponsor
Stanford University
Other
Eligibility
25 Years to 75 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Withdrawn Not applicable Interventional

Effectiveness of Manual Therapy and Exercise in Shoulder OA

NCT02587559
View directory record Official record
Conditions
Osteoarthritis
Interventions
physical therapy
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
50 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2019 · Synced Oct 11, 2026, 11:08 AM EDT
Active, not recruiting No phase listed Observational

Shoulder iD™ Primary Reversed Glenoid Outcomes Clinical Study

NCT05868148
View directory record Official record
Conditions
Rotator Cuff Tears, Rheumatoid Arthritis Shoulder, Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Fracture, Humeral, Traumatic Arthritis of Right Shoulder Region (Diagnosis), Shoulder Deformity
Interventions
Shoulder iD™ Primary Reversed Glenoid
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2035
U.S. locations
5
States / cities
San Francisco, California • Columbus, Ohio • Frisco, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 28, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Subscapularis Strength After Total Shoulder Arthroplasty

NCT03854357
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Subscapularis Rehabilitation, Standard Rehabilitation
Procedure
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 4, 2022 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Not applicable Interventional

Validity of AI in Treatment of the Musculoskeletal Conditions by Vifive

NCT05290272
View directory record Official record
Conditions
Shoulder Adhesive Capsulitis, Knee Osteoarthritis
Interventions
ViFIVE Digital Care Progrma
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Not applicable Interventional

Global® AP™ Total Shoulder Arthroplasty

NCT00719771
View directory record Official record
Conditions
Osteoarthritis
Interventions
Global® AP™ Total shoulder arthroplasty
Device
Lead sponsor
DePuy Orthopaedics
Industry
Eligibility
18 Years to 70 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
4
States / cities
Phoenix, Arizona • Asheville, North Carolina • Cincinnati, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Oct 11, 2026, 11:08 AM EDT
Enrolling by invitation No phase listed Observational

Comprehensive Reverse Shoulder Data Collection

NCT03404778
View directory record Official record
Conditions
Arthropathy of Shoulder Region, Grossly Deficient Rotator Cuff, Osteoarthritis of the Shoulder, Rheumatoid Arthritis Without Humeral Metaphyseal Defects, Post-Traumatic Arthitis
Interventions
Biomet Comprehensive Reverse Shoulder
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2036
U.S. locations
4
States / cities
Towson, Maryland • Royal Oak, Michigan • Edina, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Not applicable Interventional

Comparing the Outcome of Cemented All-Polyethylene Pegged vs. Keeled Components Through a Subscapularis Tenotomy or a Subscapularis Peel

NCT03735173
View directory record Official record
Conditions
Arthropathy Shoulder, Shoulder Pain, Shoulder Osteoarthritis, Shoulder Arthritis, Shoulder Arthropathy Associated With Other Conditions, Necrosis of Bone, Arthritis, Inflammatory Arthritis
Interventions
ReUnion TSA, pegged design, ReUnion TSA, keeled design
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 12, 2021 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Not applicable Interventional Results available

Comprehensive Shoulder System Nano IDE

NCT01936259
View directory record Official record
Conditions
Joint Disease
Interventions
Mini Stem, Nano
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
21 Years to 90 Years
Enrollment
258 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
12
States / cities
Scottsdale, Arizona • Fort Lauderdale, Florida • Fort Wayne, Indiana + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 11, 2026, 11:08 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Catalyst CSR Shoulder System for Semi or Total Shoulder Arthroplasty

NCT04968405
View directory record Official record
Conditions
Osteoarthritis Shoulder, Avascular Necrosis of the Head of Humerus, Rheumatoid Arthritis Shoulder
Interventions
Catalyst CSR Total Shoulder System
Device
Lead sponsor
Catalyst OrthoScience
Industry
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
3
States / cities
Royal Oak, Michigan • Portland, Oregon • Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 31, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Recruiting Phase 4 Interventional Accepts healthy volunteers

Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

NCT05868330
View directory record Official record
Conditions
Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
Interventions
Interscalene Catheter, Exparel Single Shot Interscalene Block
Procedure
Lead sponsor
Melinda Seering
Other
Eligibility
18 Years to 90 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 11, 2026, 11:08 AM EDT
Recruiting Not applicable Interventional

Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

NCT03921944
View directory record Official record
Conditions
Osteoarthritis of Shoulder
Interventions
CT scan of the shoulders
Diagnostic Test
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
45 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 13, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder

NCT02844738
View directory record Official record
Conditions
Osteoarthritis
Interventions
[StroMed + platelet rich plasma (PRP)]
Biological
Lead sponsor
VivaTech International, Inc.
Industry
Eligibility
18 Years to 90 Years
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2026
U.S. locations
1
States / cities
Grove City, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 11, 2026, 11:08 AM EDT
Terminated Phase 4 Interventional Results available

Comparative Effectiveness of Particulate Versus Nonparticulate Steroid Injections for Musculoskeletal Conditions

NCT04278833
View directory record Official record
Conditions
Osteoarthritis, Tendinopathy, Impingement Shoulder
Interventions
Triamcinolone or Betamethasone, Dexamethasone
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 11, 2026, 11:08 AM EDT
Active, not recruiting Not applicable Interventional

Rotator Cuff Sparing Total Arthroplasty

NCT01961986
View directory record Official record
Conditions
Osteoarthritis, Inflammatory Arthritis
Interventions
TSR - traditional subscapularis release, TSR - rotator cuff sparing
Procedure
Lead sponsor
NYU Langone Health
Other
Eligibility
21 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Oct 11, 2026, 11:08 AM EDT
Withdrawn Not applicable Interventional

Effect of Postop Rehab Methods on Outcomes Following Reverse Shoulder Arthroplasty

NCT04285606
View directory record Official record
Conditions
Rotator Cuff Tear Arthropathy, Shoulder Osteoarthritis
Interventions
Patient-led rehab with short immobilization
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 21, 2022 · Synced Oct 11, 2026, 11:08 AM EDT