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ClinicalTrials.gov public records Last synced Oct 5, 2026, 6:01 AM EDT

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Showing 73–96 of 186 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Shoulder Arthroplasty Clear all
Completed Not applicable Interventional

Do Wound Protectors Reduce Contamination in Total Shoulder Arthroplasty?

NCT06513182
View directory record Official record
Conditions
Cutibacterium Acnes
Interventions
No Alexis orthopaedic protector, Alexis orthopaedic protector
Other · Device
Lead sponsor
University of Utah
Other
Eligibility
40 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Terminated Not applicable Interventional

The Effect of Systemic or Perineural Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine

NCT01495624
View directory record Official record
Conditions
Duration of Interscalene Block
Interventions
ropivacaine plus dexamethasone anesthetic, ropivacaine plus saline plus dexamethasone anesthetic
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 27, 2016 · Synced Oct 5, 2026, 6:01 AM EDT
Enrolling by invitation Not applicable Interventional

Rehabilitation With the Shoulder Pacemaker

NCT06501859
View directory record Official record
Conditions
Shoulder Injuries
Interventions
Standard of care physical therapy, Shoulder pacemaker with physical therapy
Other · Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 5, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Recruiting No phase listed Observational

Testosterone Levels and Cutibacterium

NCT05030220
View directory record Official record
Conditions
Arthroplasty, Replacement, Shoulder
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 89 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 5, 2026, 6:01 AM EDT
Terminated Not applicable Interventional

Onlay Versus Inlay Humeral Component in Reverse Total Shoulder Arthroplasty

NCT05297305
View directory record Official record
Conditions
Arthritis Shoulder, Rotator Cuff Injuries
Interventions
Tornier Ascend Flex stem, Tornier Perform Stem Reverse+
Device
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 16, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Recruiting Not applicable Interventional

Prophylactic Conjoint Tendon Lengthening During Reverse Shoulder Arthroplasty Outcomes

NCT06729983
View directory record Official record
Conditions
Osteoarthritis Shoulder
Interventions
Prophylactic Conjoint Tendon Lengthening, Standard Reverse Shoulder Arthroplasty
Procedure
Lead sponsor
Nickolas Garbis
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 7, 2025 · Synced Oct 5, 2026, 6:01 AM EDT
Recruiting No phase listed Observational

Total Shoulder Arthroplasty Multi-Center Registry

NCT03511586
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
Not listed
Lead sponsor
Arthrex, Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2035
U.S. locations
23
States / cities
Phoenix, Arizona • Denver, Colorado • Farmington, Connecticut + 18 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Completed No phase listed Observational Results available

Safety of Treatment of Shoulder Repair

NCT04552119
View directory record Official record
Conditions
Rotator Cuff
Interventions
HEALICOIL Knotless PEEK, HEALICOIL Knotless REGENESORB
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
5
States / cities
Redwood City, California • Colorado Springs, Colorado • Denver, Colorado + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Terminated No phase listed Observational

TITAN™ Reverse Shoulder System

NCT02204228
View directory record Official record
Conditions
Osteoarthritis of the Shoulder
Interventions
TITAN™ Reverse Shoulder System (TRS)
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
21 Years and older
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
7
States / cities
Gainesville, Florida • Columbia, Maryland • Starkville, Mississippi + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers Results available

Opioid-Free Pain Protocol After Shoulder Arthroplasty

NCT05488847
View directory record Official record
Conditions
Shoulder Arthropathy, Shoulder Pain
Interventions
Celecoxib, Pregabalin, Tramadol, Dexamethasone, Acetaminophen, Ropivicaine, Epinephrine, Ketorolac, Tizanidine, Magnesium, Ibuprofen, Oxycodone Hydrochloride 5 Mg
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 10, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Terminated Phase 4 Interventional

Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusion for Post-operative Pain After Total Shoulder Arthroplasty

NCT02787226
View directory record Official record
Conditions
Postoperative Pain, Shoulder Arthritis
Interventions
Liposomal Bupivacaine Infiltration, Continuous Perineural Ropivicaine Infusion
Drug
Lead sponsor
Eric Shepard
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 9, 2018 · Synced Oct 5, 2026, 6:01 AM EDT
Not listed Not applicable Interventional

Fixed Inclination Humeral Cut

NCT03922763
View directory record Official record
Conditions
Shoulder Osteoarthritis
Interventions
Anatomical cut, Cutting guide
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2019 · Synced Oct 5, 2026, 6:01 AM EDT
Recruiting Phase 3 Interventional

Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty

NCT06902714
View directory record Official record
Conditions
Shoulder Arthroplasty
Interventions
oral tranexamic acid, Placebo
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 79 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Liposome Bupivacaine Interscalene Total Shoulder

NCT03587636
View directory record Official record
Conditions
Acute Pain
Interventions
liposome bupivacaine, Bupivacaine
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated May 2, 2022 · Synced Oct 5, 2026, 6:01 AM EDT
Enrolling by invitation No phase listed Observational

MDR - Comprehensive Primary/Micro Stem & Versa-Dial Ti Humeral Head

NCT04003311
View directory record Official record
Conditions
Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Disease, Shoulder Arthritis
Interventions
Comprehensive Primary Micro Stem, Comprehensive Anatomic Versa-Dial Titanium Humeral Head
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
18 Years and older
Enrollment
146 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
4
States / cities
Boise, Idaho • Royal Oak, Michigan • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 30, 2025 · Synced Oct 5, 2026, 6:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Irrisept C.Acnes Study

NCT03938467
View directory record Official record
Conditions
Rate of Positive Culture Growth for C.Acnes From Specimens Obtained From the Shoulders of Patients Undergoing Primary Shoulder Arthroplasty
Interventions
Antiseptic Cleanser
Drug
Lead sponsor
Orthopaedic Associates of Michigan, PC
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 21, 2024 · Synced Oct 5, 2026, 6:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Postoperative Pain Control in Total Shoulder Arthroplasty

NCT05068960
View directory record Official record
Conditions
Total Shoulder Arthroplasty
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Scripps Clinic
Other
Eligibility
50 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 21, 2025 · Synced Oct 5, 2026, 6:01 AM EDT
Completed Not applicable Interventional Results available

Sidus Stem-Free Shoulder IDE Study

NCT01878253
View directory record Official record
Conditions
Osteoarthritis, Posttraumatic Arthrosis, Rheumatoid Arthritis
Interventions
Sidus Stem-Free Total Shoulder Arthroplasty System
Device
Lead sponsor
Zimmer Biomet
Industry
Eligibility
22 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
8
States / cities
Redwood City, California • San Francisco, California • Atlanta, Georgia + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 15, 2019 · Synced Oct 5, 2026, 6:01 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Effects on Postoperative Pain of Liposomal Bupivacaine in Interscalene Blocks for Total Shoulder Arthroplasty Patients

NCT05900427
View directory record Official record
Conditions
Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty
Interventions
Liposomal bupivacaine, Bupivacaine
Drug
Lead sponsor
Johnny K. Lee
Other
Eligibility
18 Years to 90 Years
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Skokie, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 5, 2026, 6:01 AM EDT
Terminated Phase 4 Interventional Results available

TXA in Revision Total Shoulder Arthroplasty

NCT04650698
View directory record Official record
Conditions
Arthropathy Shoulder
Interventions
Tranexamic acid (TXA) injection
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 12, 2024 · Synced Oct 5, 2026, 6:01 AM EDT
Completed Phase 4 Interventional

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

NCT06109415
View directory record Official record
Conditions
Postoperative Pain, Total Shoulder Arthroplasty, Multimodal Analgesia
Interventions
HTX-011, Bupivacaine Hydrochloride, Ibuprofen, Acetaminophen, Luer lock applicator
Drug · Device
Lead sponsor
Heron Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
5
States / cities
Little Rock, Arkansas • Jenks, Oklahoma • Bellaire, Texas + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2023 · Synced Oct 5, 2026, 6:01 AM EDT
Completed Phase 4 Interventional Results available

LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs

NCT03887650
View directory record Official record
Conditions
Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
Interventions
Liposomal Bupivicaine 1.3%, Bupivacaine 0.5%
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years to 100 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 15, 2023 · Synced Oct 5, 2026, 6:01 AM EDT
Completed No phase listed Observational Results available

Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty

NCT02052466
View directory record Official record
Conditions
Osteoarthritis, Rotator Cuff Tear Arthropathy, Reverse Total Shoulder Arthroplasty, Scapular Notching
Interventions
Not listed
Lead sponsor
Eric Ricchetti
Other
Eligibility
Not listed
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 9, 2017 · Synced Oct 5, 2026, 6:01 AM EDT
Recruiting No phase listed Observational

Return to Golf After Orthopaedic Surgery

NCT05675618
View directory record Official record
Conditions
Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
432 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2026 · Synced Oct 5, 2026, 6:01 AM EDT