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Showing 1–24 of 355 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Shoulder Disease Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

NCT05754190
View directory record Official record
Conditions
Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary, Fibromyalgia, Secondary, Fibromyalgia, Irritable Bowel Syndrome, Chronic Headache Disorder, Chronic Migraine, Chronic Pelvic Pain Syndrome, Temporomandibular Joint Disorders, Endometriosis-related Pain, Arthritis, Chronic Low-back Pain, Failed Back Surgery Syndrome, Post Herpetic Neuralgia, Neuropathic Pain, Painful Diabetic Neuropathy, Painful Bladder Syndrome, Trauma-related Wound, Trauma, Multiple, Chronic Pain Syndrome, Chronic Shoulder Pain
Interventions
SOMA pain manager smartphone application
Device
Lead sponsor
Brown University
Other
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Embodiment in Virtual Reality as a Telemedicine Digital Therapeutic for the Treatment of Chronic Shoulder Pain

NCT05375500
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Shoulder Pain
Interventions
telemedicine digital therapeutic
Device
Lead sponsor
Karuna Labs Inc.
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Gatos, California
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Buckets vs. Braces Prospective Study

NCT06904430
View directory record Official record
Conditions
Elbow Pain, Shoulder Pain
Interventions
Bucket Group, Brace Group
Other · Device
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
8 Years to 12 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jul 22, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)

NCT07125833
View directory record Official record
Conditions
Degenerative Joint Disease of Shoulder
Interventions
Cryoneurolysis, No cryoneurolysis
Device · Other
Lead sponsor
North Texas Medical Research Institute, PLLC
Other
Eligibility
30 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Rockwall, Texas
Source: ClinicalTrials.gov public record
Updated Aug 14, 2025 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Tranexamic Acid in Reverse Total Shoulder Arthroplasty

NCT02043132
View directory record Official record
Conditions
Shoulder Joint Disease, Complications; Arthroplasty, Intraoperative Complications, Blood Loss, Surgical
Interventions
Tranexamic Acid, Placebo
Drug
Lead sponsor
Corewell Health East
Other
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Royal Oak, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 18, 2017 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Tension of THERABAND® Kinesiology Tape on Shoulder Pain

NCT02686437
View directory record Official record
Conditions
Shoulder Pain
Interventions
TheraBand Kinesiology Tape
Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 30, 2018 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Efficacy of First Time Anterior Shoulder Decision Tool

NCT02656277
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Decision Tool, Information on Shoulder Dislocation
Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 30, 2017 · Synced Jul 22, 2026, 6:57 AM EDT
Suspended Not applicable Interventional

Porcine Extracellular Matrix Nerve Wrap in Neck Dissection for Head and Neck Cancer

NCT07268092
View directory record Official record
Conditions
Head and Neck Cancer, Neck Dissection, Postoperative Complications
Interventions
Porcine Extracellular Matrix Nerve Wrap (AxoGuard Nerve Protector™)
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 22, 2026, 6:57 AM EDT
Active, not recruiting No phase listed Observational

Pyrocarbon Clinical Follow-up Study

NCT05049993
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Avascular Necrosis, Traumatic Arthritis
Interventions
Aequalis Pyrocarbon Humeral Head
Device
Lead sponsor
Stryker Trauma and Extremities
Industry
Eligibility
22 Years and older
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
8
States / cities
Denver, Colorado • Fort Lauderdale, Florida • New Orleans, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Jul 22, 2026, 6:57 AM EDT
Recruiting Not applicable Interventional

Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure

NCT07216820
View directory record Official record
Conditions
Shoulder Surgery, Obesity
Interventions
Ultrasound-Guided Interscalene Brachial Plexus Block, Phrenic-Sparing Block Combination (Experimental), Bupivacaine HCl 0.5% Injectable Solution, Dexamethasone 4mg
Procedure · Drug
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jul 22, 2026, 6:57 AM EDT
Not listed No phase listed Observational

Evaluation of Surgical Positioning in Arthroscopic Shoulder Stabilization

NCT05160909
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Beach Chair Position, Lateral Decubitus Position
Procedure
Lead sponsor
Rothman Institute Orthopaedics
Other
Eligibility
18 Years and older
Enrollment
556 participants
Timeline
2021 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 15, 2021 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Phase 2Phase 3 Interventional

Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis

NCT00640939
View directory record Official record
Conditions
Rotator Cuff Tendonitis, Bicipital Tendonitis, Subdeltoid Bursitis of the Shoulder, Subacromial Bursitis of the Shoulder, Medial Epicondylitis of the Elbow, Lateral Epicondylitis of the Elbow, DeQuervain's Tenosynovitis of the Wrist
Interventions
diclofenac sodium, Matching Placebo
Drug
Lead sponsor
Cerimon Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2008 · Synced Jul 22, 2026, 6:57 AM EDT
Active, not recruiting Phase 2 Interventional

Stromal Vascular Fraction Cell Therapy to Improve the Repair of Rotator Cuff Tears

NCT03332238
View directory record Official record
Conditions
Rotator Cuff Tear, Muscle Atrophy, Tendon Tear
Interventions
Autologous Stomal Vascular Fraction Material, Ringer's solution
Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
45 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Forces and Translation Distance During an Inferior Glide of the Shoulder

NCT04775628
View directory record Official record
Conditions
Asymptomatic Condition
Interventions
Inferior glide humerus in GH joint
Procedure
Lead sponsor
Dr. Rob Sillevis,
Other
Eligibility
18 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fort Myers, Florida
Source: ClinicalTrials.gov public record
Updated Apr 6, 2022 · Synced Jul 22, 2026, 6:57 AM EDT
Not listed Phase 4 Interventional

IAL vs PS for Anterior Shoulder Dislocations

NCT03625076
View directory record Official record
Conditions
Shoulder Dislocation
Interventions
Intra-articular Lidocaine, Procedural Sedation with etomidate or propofol
Drug
Lead sponsor
Kendall Healthcare Group, Ltd.
Industry
Eligibility
18 Years to 70 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 12, 2019 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Intercostobrachial Nerve Block's Effect on Pain Control After Shoulder Replacement

NCT06042608
View directory record Official record
Conditions
Postoperative Pain, Acute, Shoulder Pain
Interventions
intercostobrachial nerve block
Procedure
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional Results available

Electrical Stimulation for the Treatment of Post-Stroke Shoulder Pain

NCT01094301
View directory record Official record
Conditions
Shoulder Pain
Interventions
The SPR System
Device
Lead sponsor
SPR Therapeutics, Inc.
Industry
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
4
States / cities
New York, New York • Charlotte, North Carolina • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 11, 2018 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Not applicable Interventional

Safe and Effective Shoulder Exercise Training in Manual Wheelchair Users With SCI

NCT02777281
View directory record Official record
Conditions
Shoulder Pain, Spinal Cord Injury
Interventions
Shoulder pain and SCI, Shoulder pain and able bodies
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Jul 22, 2026, 6:57 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Freehand Ultrasound to Evaluate Scapular Kinematics in People With Paraplegia

NCT02357914
View directory record Official record
Conditions
Spinal Cord Injuries, Shoulder Impingement Syndrome
Interventions
Not listed
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 14, 2018 · Synced Jul 22, 2026, 6:57 AM EDT
Recruiting No phase listed Observational

Return to Golf After Orthopaedic Surgery

NCT05675618
View directory record Official record
Conditions
Hip Osteoarthritis, Knee Osteoarthritis, Shoulder Osteoarthritis
Interventions
Not listed
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
18 Years and older
Enrollment
432 participants
Timeline
2023 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 12, 2026 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Phase 2 Interventional

Exercise and Manual Therapy for Shoulder Subacromial Impingement Syndrome

NCT00632996
View directory record Official record
Conditions
Shoulder Impingement Syndrome
Interventions
Rehabilitation
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years to 75 Years
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2014
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 20, 2015 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Biopsychosocial Influence on Shoulder Pain

NCT02620579
View directory record Official record
Conditions
Shoulder Pain
Interventions
Propranolol LA (60 mg), Placebo, Shoulder Anatomy Education, Pain Processing Education
Drug · Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 64 Years
Enrollment
264 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Jul 22, 2026, 6:57 AM EDT
Withdrawn Not applicable Interventional

Amnion-Based Injections in the Shoulder

NCT03770546
View directory record Official record
Conditions
Osteoarthritis of the Shoulder, Adhesive Capsulitis
Interventions
Amnion Injection, Betamethasone injection
Biological · Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 25, 2021 · Synced Jul 22, 2026, 6:57 AM EDT
Completed Phase 4 Interventional

Interscalene Single Shot With Plain Bupivacaine Versus Liposomal Bupivacaine for Arthroscopic Shoulder Surgery

NCT03638960
View directory record Official record
Conditions
Shoulder Pain, Postoperative Pain
Interventions
Bupivacaine liposome, Bupivacaine Hydrochloride
Drug
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 14, 2024 · Synced Jul 22, 2026, 6:57 AM EDT