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Showing 1–24 of 105 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Siblings Clear all
Completed Not applicable Interventional

Efficacy of IMPACT in Infant Siblings of Children With ASD

NCT03274622
View directory record Official record
Conditions
Autism Spectrum Disorder
Interventions
Impact Parent Training, No Impact
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
12 Months to 18 Months
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
2
States / cities
Nashville, Tennessee • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 1, 2019 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Behavioral Intervention With Foster Families

NCT05405972
View directory record Official record
Conditions
Family Relationship, Sibling Relations, Behavior, Social
Interventions
The Connected Family Series - For Foster Families
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
7 Years to 85 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 2, 2024 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Effect of Oocyte Vitrification on Fertilization Rate, Embryo Quality and Development

NCT01422395
View directory record Official record
Conditions
Fertility
Interventions
Freezing
Procedure
Lead sponsor
Main Line Fertility Center
Other
Eligibility
21 Years to 37 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Bryn Mawr, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2014 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Not applicable Interventional

Family Functioning and Child Behavior When a Sibling is Critically Ill

NCT00912626
View directory record Official record
Conditions
Child Behavior
Interventions
One week follow up assessment results
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 11, 2015 · Synced Sep 2, 2026, 5:45 AM EDT
Completed No phase listed Observational

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders

NCT00055055
View directory record Official record
Conditions
Rheumatoid Arthritis, Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathies
Interventions
Not listed
Lead sponsor
National Institute of Environmental Health Sciences (NIEHS)
NIH
Eligibility
2 Years and older
Enrollment
1,056 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
3
States / cities
Bethesda, Maryland • Research Triangle Park, North Carolina • Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Phase 3 Interventional

Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseases

NCT00438958
View directory record Official record
Conditions
Chronic Myeloproliferative Disorders, Graft Versus Host Disease, Leukemia, Lymphoma, Myelodysplastic Syndromes, Secondary Myelofibrosis
Interventions
filgrastim, allogeneic bone marrow transplantation, peripheral blood stem cell transplantation
Biological · Procedure
Lead sponsor
The Canadian Blood and Marrow Transplant Group
Network
Eligibility
16 Years to 65 Years
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 4, 2014 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Not applicable Interventional Results available

Engaging Siblings of Adults With Autism in Future Planning

NCT03374072
View directory record Official record
Conditions
Autistic Disorder
Interventions
Siblings FORWARD program, Information Only Condition
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 2, 2026, 5:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Metabolic Syndrome in Young Patients Who Are Acute Lymphoblastic Leukemia Survivors and Their Healthy Siblings

NCT00897078
View directory record Official record
Conditions
Leukemia
Interventions
laboratory biomarker analysis, medical chart review, metabolic assessment, questionnaire administration, assessment of therapy complications
Other · Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
8 Years to 21 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 12, 2013 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Phase 3 Interventional Results available

Stem Cell Transplantation in Individuals With Multiple Myeloma (BMT CTN 0102)

NCT00075829
View directory record Official record
Conditions
Multiple Myeloma
Interventions
One Autologous Transplant, Non-Myeloablative Allogeneic Transplant, Second Autologous Transplant, Thalidomide, Dexamethasone, Observation
Procedure · Drug · Behavioral
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Up to 70 Years
Enrollment
710 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2013
U.S. locations
36
States / cities
Birmingham, Alabama • Phoenix, Arizona • Duarte, California + 28 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2021 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SIB-Time Web-application Tool for Typically Developing Siblings

NCT04633473
View directory record Official record
Conditions
Family Relations, Sibling Relations
Interventions
SIB-Time Web-Application Tool
Behavioral
Lead sponsor
Oregon Research Behavioral Intervention Strategies, Inc.
Industry
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Jul 4, 2024 · Synced Sep 2, 2026, 5:45 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Genetics Of Autoimmunity In Type I Diabetes

NCT03648918
View directory record Official record
Conditions
Type1diabetes, Diabetes Mellitus, Type 1, Type1 Diabetes Mellitus, Diabetes Mellitus
Interventions
Blood Collection
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
2 Years and older
Enrollment
4,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2050
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 15, 2026 · Synced Sep 2, 2026, 5:45 AM EDT
Recruiting Phase 2 Interventional

Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell Antibody

NCT06358638
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Daratumumab, Alemtuzumab, Sirolimus, Total Body Irradiation
Drug · Radiation
Lead sponsor
Children's National Research Institute
Other
Eligibility
2 Years to 25 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2054
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 25, 2025 · Synced Sep 2, 2026, 5:45 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Social Isolation and Aging in Schizophrenia

NCT07419321
View directory record Official record
Conditions
Schizophrenia and Related Disorders
Interventions
Not listed
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
40 Years to 70 Years
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Sep 2, 2026, 5:45 AM EDT
Completed No phase listed Observational

Pilot Study of Educational Interventions in Pediatric Hematopoietic Stem Cell Donors to Increase Knowledge of Donation and Transplantation Procedures

NCT01445158
View directory record Official record
Conditions
Normal Donors
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
10 Years to 26 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Sep 2, 2026, 5:45 AM EDT
Active, not recruiting Phase 2 Interventional

Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation

NCT04018937
View directory record Official record
Conditions
Sickle Cell Disease
Interventions
Alemtuzumab, Fludarabine, Melphalan
Drug
Lead sponsor
Emory University
Other
Eligibility
2 Years to 13 Years
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
13
States / cities
Birmingham, Alabama • Phoenix, Arizona • New Haven, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Nov 24, 2024 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of a Resiliency Intervention for Siblings of Children With Autism Spectrum Disorder (ASD)

NCT04369417
View directory record Official record
Conditions
Stress
Interventions
Relaxation Response Resiliency Program for Siblings of Children with ASD
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years to 17 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Sep 2, 2026, 5:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Endothelial Function, Arterial Stiffness and Components

NCT01439217
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia
Interventions
Not listed
Lead sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Other
Eligibility
8 Years to 28 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 16, 2013 · Synced Sep 2, 2026, 5:45 AM EDT
Recruiting Not applicable Interventional

Sibwatch: Optimizing Intervention Options for Infants and Toddler Siblings of Autistic Children

NCT07069413
View directory record Official record
Conditions
Autism Sibling
Interventions
tele-ImPACT
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
6 Months to 24 Months
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2032
U.S. locations
2
States / cities
Nashville, Tennessee • Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 2, 2026, 5:45 AM EDT
Completed No phase listed Observational

Impact of Serious Pediatric Illness on Parent and Sibling Health

NCT03971344
View directory record Official record
Conditions
Family Members of: Newborns Extremely Premature, Family Members of: New Pediatric Oncology Patients, Family Members of: Critical Congenital Heart Defect Patients, Family Members of: Children Severe Neurological Impairment
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Not listed
Enrollment
161,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 30, 2020 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Phase 3 Interventional

Active Immunization of Sibling Bone Marrow Transplant Donors Against Purified Myeloma Protein of the Recipient Undergoing Allogeneic Bone Marrow Transplantation

NCT00001561
View directory record Official record
Conditions
Graft vs Host Disease, Multiple Myeloma
Interventions
Myeloma Immunoglobulin Idiotype Vaccine-KLH, GM-CSF
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 60 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 23, 2007 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

SibACCESS: Developing a Telehealth Intervention to Address Unmet Psychosocial Needs of Siblings of Children With Cancer

NCT04889755
View directory record Official record
Conditions
Siblings, Childhood Cancer, Pediatric Cancer, Posttraumatic Stress Disorder
Interventions
SibACCESS
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
12 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 16, 2025 · Synced Sep 2, 2026, 5:45 AM EDT
Terminated Phase 2 Interventional

A Safety and Tolerability Study of CDX-301 With or Without Plerixafor for Stem Cell Mobilization in Matched Related Allogeneic Donor/Recipient Sibling Transplant Pairs

NCT02200380
View directory record Official record
Conditions
For Donors, Related Donors Giving Peripheral Blood Stem Cells (PBSC) to a Sibling, For Recipients, Acute Myelogenous Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Myelodysplastic Syndrome (MDS), Chronic Myelogenous Leukemia (CML), Non-Hodgkins Lymphoma (NHL), Hodgkins Disease (HD), Chronic Lymphocytic Leukemia (CLL)
Interventions
CDX-301, CDX-301 and plerixafor
Drug
Lead sponsor
Celldex Therapeutics
Industry
Eligibility
18 Years to 70 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
8
States / cities
Los Angeles, California • Atlanta, Georgia • Indianapolis, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2017 · Synced Sep 2, 2026, 5:45 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Milieu Teaching-AV: Adaptation of Milieu Teaching That Encourages Looking to the Mouth

NCT07494513
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Autism, Susceptibility to, 6
Interventions
Milieu Teaching-AV, Milieu Teaching-NoAV
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
5 Months to 13 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2029
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Sep 2, 2026, 5:45 AM EDT
Completed Phase 2 Interventional Results available

Chemotherapy, Stem Cell Transplantation and Donor and Patient Vaccination for Treatment of Multiple Myeloma

NCT00006184
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Myeloma Immunoglobulin Idiotype Vaccine, Bortezomib, Cyclophosphamide, Cyclosporine, Doxorubicin hydrochloride, Etoposide, Fludarabine phosphate, Prednisone, Vincristine Sulfate, Methotrexate, GMCSF (granulocyte macrophage colony stimulating factor), GCSF (granulocyte colony stimulating factor)
Drug · Biological
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 19, 2017 · Synced Sep 2, 2026, 5:45 AM EDT