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ClinicalTrials.gov public records Last synced Nov 4, 2026, 9:57 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1609–1632 of 4,720 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Signs and Symptoms, Respiratory Clear all

Conditions: Bronchopulmonary Dysplasia, Retinopathy of Prematurity, Prematurity, Pulmonary Disease
Interventions: Not listed
Lead sponsor: National Institute of Environmental Health Sciences (NIEHS); NIH
Eligibility: Not listed
Enrollment: 1,068 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Research Triangle Park, North Carolina

Conditions: Asthma, Obesity, Insulin Resistance
Interventions: Probiotic, Placebo; Dietary Supplement
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 18 Years to 99 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Advanced or Metastatic Solid Tumors, Lung Cancer, Breast Cancer, Head and Neck Squamous Cell Carcinoma, Endometrial Cancer, Melanoma, CRC, Urothelial Carcinoma, Cholangiocarcinoma
Interventions: NC318; Drug
Lead sponsor: NextCure, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 109 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 6
States / cities: Los Angeles, California • New Haven, Connecticut • Hackensack, New Jersey + 3 more

Conditions: Liver Disease Chronic, Muscle Weakness, Respiratory Insufficiency
Interventions: Inspiratory Muscle Training; Other
Lead sponsor: University of Miami; Other
Eligibility: 18 Years and older
Enrollment: 37 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Miami, Florida

Conditions: Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure, Acute Kidney Injury, Delirium Confusional State, Shock
Interventions: Point-of-care large language model decision support (ChatGPT-5); Other
Lead sponsor: MetroWest Artificial Intelligence Research Workgroup; Other
Eligibility: 18 Years and older
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Framingham, Massachusetts

Conditions: Chronic Obstructive Pulmonary Disease, Physical Activity, Health Behavior
Interventions: Telephonic health coaching; Behavioral
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years and older
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Pulmonary Disease, Chronic Obstructive
Interventions: 62.5/25mcg, 62.5mcg, 25mcg, Placebo; Drug
Lead sponsor: GlaxoSmithKline; Industry
Eligibility: 40 Years and older
Enrollment: 1,538 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 37
States / cities: Tucson, Arizona • Los Angeles, California • Ormond Beach, Florida + 33 more

Conditions: Hereditary Hemorrhagic Telangiectasia (HHT), Epistaxis
Interventions: Topical sirolimus ointment; Drug
Lead sponsor: Columbia University; Other
Eligibility: 18 Years and older
Enrollment: 27 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Obesity, Premature Recovery From Anesthesia
Interventions: Nuvigil, Placebo; Drug
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 18 Years to 75 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Ventilator Associated Pneumonia
Interventions: Education; Behavioral
Lead sponsor: Canadian Critical Care Trials Group; Other
Eligibility: 17 Years and older
Enrollment: 1,320 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2010
U.S. locations: 1
States / cities: Danville, Pennsylvania

Conditions: Child Maltreatment, Interpersonal Relations, Victimisation, Psychopathology, Electrocardiography
Interventions: Debrief; Behavioral
Lead sponsor: University of South Carolina; Other
Eligibility: 13 Years to 17 Years
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Columbia, South Carolina

Conditions: Aortic Stenosis
Interventions: Tadalafil, Placebo; Drug
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Cancer, PDAC - Pancreatic Ductal Adenocarcinoma, NSCLC (Non-small Cell Lung Cancer), CRC (Colorectal Cancer), Advanced Solid Tumors
Interventions: ALTA3263, cetuximab, mFOLFOX6, Pembrolizumab, Pemetrexed + Cisplatin /Carboplatin, mFOLFIRINOX, GnP, Midazolam; Drug
Lead sponsor: Alterome Therapeutics, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 448 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2029
U.S. locations: 14
States / cities: Orlando, Florida • Tampa, Florida • Boston, Massachusetts + 7 more

Conditions: Respiratory Failure, Hypotension and Shock, Hypotension on Induction, Intubation Complication, Anesthesia Intubation Complication
Interventions: Norepinephrine, Lactated Ringers, Intravenous, normal saline, Plasma-lyte; Drug
Lead sponsor: Wright State University; Other
Eligibility: 18 Years and older
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Dayton, Ohio

Conditions: Non-small Cell Lung Cancer, Adenocarcinoma, Stage IV
Interventions: Rigosertib, Nivolumab; Drug
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 18 Years and older
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Obstructive Sleep Apnea
Interventions: AD036 Dose 1, AD036 Dose 2, AD036 Dose 3, Placebo; Drug
Lead sponsor: Apnimed; Industry
Eligibility: 25 Years to 70 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019
U.S. locations: 12
States / cities: Glendale, Arizona • Little Rock, Arkansas • Redwood City, California + 9 more

Conditions: Post-acute COVID-19 Syndrome
Interventions: naltrexone, Placebo; Drug · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 6 Years to 25 Years
Enrollment: 1,300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 13
States / cities: Birmingham, Alabama • Chula Vista, California • Denver, Colorado + 10 more

Conditions: Hemothorax; Traumatic
Interventions: CLR Irrigator, Serial Lavage and Drainage, 28 Fr Open Chest Tube, Percutaneous 14Fr Chest Tube; Device · Procedure
Lead sponsor: University of Pennsylvania; Other
Eligibility: 15 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Interventions: Blood drawing, Bronchoalveolar lavage during indicated bronchoscopy; Procedure
Lead sponsor: University of Michigan; Other
Eligibility: 40 Years and older
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2014
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Apnea, Hypoventilation, Hypoxemia
Interventions: Stimulator active device, Stimulator sham Device; Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2017
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Common Cold, Infections, Upper Respiratory Tract
Interventions: Dextromethorphan, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 6 Years to 11 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 4
States / cities: Pinellas Park, Florida • Indianapolis, Indiana • Gresham, Oregon + 1 more

Conditions: Chronic Obstructive Pulmonary Disease
Interventions: Not listed
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: Not listed
Enrollment: 2,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1994 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Asthma, Asthma in Children, Wheezing, Pediatric Asthma
Interventions: RESP™ Biosensor; Device
Lead sponsor: Strados Labs, Inc.; Industry
Eligibility: 4 Years to 17 Years
Enrollment: 36 participants
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Chronic Critical Illness, Prolonged Mechanical Ventilation
Interventions: Not listed
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years and older
Enrollment: 589 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 6
States / cities: Denver, Colorado • The Bronx, New York • Chapel Hill, North Carolina + 3 more

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Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity

Probiotics and Insulin Resistance in Obese Asthmatics

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

Inspiratory Muscle Training Post-Liver Transplant

Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial

Physical Activity Coaching in Chronic Obstructive Pulmonary Disease (COPD)

A 24-week Evaluation of GSK573719/Vilanterol (62.5/25mcg) and Components in COPD

Topical TOR-582 Treatment of Epistaxis in HHT

Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients

Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia

Beneficial or Fostering Future Struggles (B.F.F.s)? Characterizing the Role of Friends in the Development of 13- to 17-Year-Old Adolescents

Aortic Stenosis and PhosphodiEsterase iNhibition With Aortic Valve Replacement (ASPEN-AVR): A Pilot Study

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure

Rigosertib Plus Nivolumab for KRAS+ NSCLC Patients Who Progressed on First-Line Treatment

Trial of AD036 in Obstructive Sleep Apnea

The Study of Brave-LC LDN Treatment Trial

Traumatic Hemothorax Drainage and Daily Lavage

Comparison of Alveolar Macrophages in Individuals With COPD Versus Smokers With Normal Pulmonary Function

Peripheral Nerve Stimulation to Reduce Hypoxic Events

Acute Cough Study In Children

Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study

Wearable Auscultation Device Validation in Children

Prediction of Functional Outcomes From Chronic Critical Illness