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Conditions: Child Development Disorder, Development Delay
Interventions: Young Children's Participation and Environment Measure (YC-PEM) electronic patient-reported outcome (e-PRO); Behavioral
Lead sponsor: University of Illinois at Chicago; Other
Eligibility: 3 Months to 36 Months
Enrollment: 76 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Denver, Colorado

Conditions: Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD, Autism Spectrum Disorder, Epilepsy
Interventions: Sulfonylurea; Drug
Lead sponsor: Royal Devon and Exeter NHS Foundation Trust; Other
Eligibility: 2 Years to 50 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Growth & Development, Obesity, Cardiovascular Risk Factor, Metabolic Syndrome, Food Allergy, Cognitive Developmental Delay
Interventions: Infant egg consumption (i.e., age of introduction and frequency of intake); Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 0 Years to 15 Years
Enrollment: 5,374 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 1999 – 2019
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Pediatric Obesity
Interventions: Not listed
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 8 Years to 11 Years
Enrollment: 250 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Microcephaly, Hyperkinesis With Developmental Delay, Global Developmental Delay
Interventions: Acquire Therapy; Behavioral
Lead sponsor: Virginia Polytechnic Institute and State University; Other
Eligibility: 6 Months to 15 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Roanoke, Virginia

Conditions: Child Development, Infant Development, Developmental Delay, Language Development
Interventions: Building Capacity for Infant Achievements in Child Care; Behavioral
Lead sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.; Other
Eligibility: 18 Years to 100 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Developmental Delay
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 9 Months to 65 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2031
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Mental Retardation, Developmental Delay Disorder
Interventions: risperidone, clozapine, olanzapine; Drug
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 6 Years to 60 Years
Enrollment: 50 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2001
U.S. locations: 1
States / cities: Lawrence, Kansas

Conditions: Speech Sound Disorder, Phonology Disorder, Phonology Impairment, Phonological Disorder, Articulation Disorders in Children, Developmental Phonological Disorder, Speech Disorders, Speech Delay, Articulation Disorders, Developmental
Interventions: articulation therapy, phonologic treatment; Behavioral
Lead sponsor: University of Wyoming; Other
Eligibility: 4 Years to 8 Years
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Laramie, Wyoming

Conditions: Language Development, Language Delay, Mother-Infant Interaction, Maternal Behavior
Interventions: Reading intervention, Infant bonding, LENA recording, LENA linguistic feedback, LENA summary; Behavioral
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 23 Weeks to 31 Weeks
Enrollment: 67 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Epilepsy, Mental Retardation, Developmental Disabilities
Interventions: Swallow instruction; Behavioral
Lead sponsor: Children's National Research Institute; Other
Eligibility: 4 Years to 18 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
Interventions: Not listed
Lead sponsor: University of Arkansas; Other
Eligibility: 0 Years to 17 Years
Enrollment: 297 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2027
U.S. locations: 1
States / cities: Memphis, Tennessee

Conditions: Developmental Delay Disorders, Chromosome Deletion, Mental Retardation, Sleep Disorders, Circadian Rhythm, Self Injurious Behavior
Interventions: dTR Melatonin (NIH CC PDS), Phototherapy (Bright Light), Melatonin CR; Drug · Device
Lead sponsor: National Human Genome Research Institute (NHGRI); NIH
Eligibility: 3 Years to 45 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2018
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Development Delay, Social Skills, Parents
Interventions: Parent Training, Video Modeling; Behavioral
Lead sponsor: University of Nevada, Las Vegas; Other
Eligibility: 3 Years and older
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Developmental Delays, Global Developmental Delay, Stroke, Cancers, Seizures Disorders, Behavior Problems, Feeding Disorder, Developmental Delay in Feeding
Interventions: Animal Assisted Therapy; Behavioral
Lead sponsor: Children's Hospitals and Clinics of Minnesota; Other
Eligibility: Not listed
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 1
States / cities: Saint Paul, Minnesota

Conditions: Angelman Syndrome, Nervous System Diseases
Interventions: Betaine, Creatine, Metafolin, Vitamin B12; Drug
Lead sponsor: University of California, San Diego; Other
Eligibility: 1 Day to 5 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 4
States / cities: San Diego, California • Boston, Massachusetts • Greenwood, South Carolina + 1 more

Conditions: Parent-Child Relations, Parenting, Child Behavior, Development Delay, Developmental Disability, Development Disorder, Child
Interventions: Family Advice and Support Text and Telephone (FASTT) program; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: Not listed
Enrollment: 39 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 2
States / cities: Los Angeles, California • Eugene, Oregon

Conditions: Language Delay, Language Development, Feeding; Difficult, Newborn, Mother-Infant Interaction, Maternal Behavior
Interventions: Oromotor stimulation, Reading curriculum, LENA recording, LENA linguistic feedback, No oromotor stimulation; Behavioral
Lead sponsor: Women and Infants Hospital of Rhode Island; Other
Eligibility: 23 Weeks to 30 Weeks
Enrollment: 124 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Autism Spectrum Disorder, Autism, Developmental Delay, Autism, Early Infantile, Autism, Infantile
Interventions: Assessment by Expert Clinician During Behavioral Intervention (ABA or similar), Assessment by the EarliPoint Assessment For Autism Spectrum Disorder; Behavioral · Device
Lead sponsor: EarliTec Diagnostics, Inc; Industry
Eligibility: 15 Months to 84 Months
Enrollment: 325 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2025
U.S. locations: 9
States / cities: Phoenix, Arizona • Glendale, California • San Rafael, California + 6 more

Conditions: Genetic Disorder, Asperger Disorder, Autism Spectrum Disorder, Fragile X Syndrome, Developmental Delay
Interventions: Not listed
Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); NIH
Eligibility: 1 Year to 99 Years
Enrollment: 96 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2025
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Developmental Delay
Interventions: Playgroup; Behavioral
Lead sponsor: Florida Gulf Coast University; Other
Eligibility: 15 Months to 5 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2022
U.S. locations: 1
States / cities: Fort Myers, Florida

Conditions: Seizures, Development Delay, Anesthetic Neurotoxicity
Interventions: Change in plan of care based on MRI results; Diagnostic Test
Lead sponsor: Baylor College of Medicine; Other
Eligibility: Up to 1095 Days
Enrollment: 561 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Autism Spectrum Disorder, Developmental Delay
Interventions: infant telehelp; Behavioral
Lead sponsor: University of California, Davis; Other
Eligibility: 5 Months to 12 Months
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Language Delay, Substance Use Disorders, Language Disorders in Children, Language Development, Prevention Intervention
Interventions: Comilia Group, Interaction Review Enhancement, Practical Support Enhancement; Behavioral
Lead sponsor: University of Oregon; Other
Eligibility: 18 Years and older
Enrollment: 244 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Eugene, Oregon

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Implementation of Electronic Shared Decision-Making Support for Early Intervention

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

Effects of Infant Egg Consumption on Child Health and Cognition Development

Developmental Trajectories of Reinforcer Pathology and Childhood Obesity

Intensive Therapy for Children With Microcephaly, Hyperkinetic Movements, or Global Developmental Delay

Expanding the Infant Achievements Intervention Through Community Partnerships

Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder

Atypical Neuroleptic Drugs in People With Mental Retardation/Developmental Delay

Age-related Correlates of Treatment for Late-acquired Sounds

A Language Intervention Study of Preterm Infants

Use of Sustained Release Antiepileptic Medication (Depakote® ER) for Pediatric Epilepsy in a Mental Retardation/Developmental Disorder Population

Mitochondrial Dysfunction in Autism Spectrum Disorder

Treatment Strategies for Children With Smith-Magenis Syndrome

Home-Based Social Skills Intervention for Young Children With Developmental Delays

Animal Assisted Therapy in a Pediatric Setting

Dietary Supplements for the Treatment of Angelman Syndrome

FASTT Telehealth Behavioral Support Service for Caregivers of Children With Developmental Delay or Disability

Combined Oral Motor Stimulation and Language on Preterm Infant Feeding

Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children

Pediatric Patients With Metabolic or Other Genetic Disorders

Measuring the Feasibility and Preliminary Efficacy of Therapeutic Playgroups in Early Intervention

Review of Diagnostic Yield of MRI Brain Results in Children Under Age 3 Years

Pilot Study: A Telehealth Intervention for Caregivers of Infants With Early Signs of Autism Spectrum Disorder

Prevent Language Delays and Disorders Among Children of Caregivers With Substance Use Disorders With Community Groups and Individualized Services