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Showing 1–24 of 27 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Single-sided Deafness Clear all
Completed Not applicable Interventional

Hearing Outcomes With the Osia 3 Sound Processor Compared to the Osia 2 Sound Processor in Adult Osia Implant Recipients

NCT07156461
View directory record Official record
Conditions
Hearing Loss, Mixed, Hearing Loss, Conductive, Single-Sided Deafness, Bone Conduction
Interventions
Cochlear™ Osia® System (Osia® 2), Cochlear™ Osia® System (Osia® 3)
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 23, 2026, 6:15 PM EDT
Terminated Not applicable Interventional Results available

Cochlear Implantation for Treatment of Single-sided Deafness

NCT02532972
View directory record Official record
Conditions
Total Unilateral Deafness, Unilateral Partial Deafness
Interventions
Med-el MAESTRO Cochlear Implant with Flex 28 electrode array
Device
Lead sponsor
Dr. Daniel Lee
Other
Eligibility
18 Years and older
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 4, 2020 · Synced Jul 23, 2026, 6:15 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implants in Young Children With SSD

NCT05775367
View directory record Official record
Conditions
Single Sided Deafness, Unilateral Deafness, Hearing Loss, Unilateral, Hearing Loss, Congenital Hearing Loss, Deafness One Ear
Interventions
Cochlear Implant
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
7 Months to 71 Months
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2030
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jul 23, 2026, 6:15 PM EDT
Recruiting Not applicable Interventional

Perceptual Adaptation Following Cochlear Implantation (Aim 3a)

NCT07039435
View directory record Official record
Conditions
Sensorineural Hearing Loss, Cochlear Implantation, Perceptual Adaptation
Interventions
Alternative Frequency Mapping
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Results available

Bone Conduction Auditory Performance Via the Tooth for Single-Sided Deafness

NCT00977314
View directory record Official record
Conditions
Unilateral Hearing Loss
Interventions
The Sonitus Bone Conduction Hearing System, SoundBite, SoundBite Hearing System
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Redwood City, California • San Jose, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2014 · Synced Jul 23, 2026, 6:15 PM EDT
Enrolling by invitation Not applicable Interventional

Impact of Anatomy-Based Cochlear Implant Programming on Early Performance

NCT06734039
View directory record Official record
Conditions
Hearing Loss, Unilateral, Cochlear Implants, Hearing Loss, Sensorineural, Single-Sided Deafness (SSD), Asymmetric Hearing Loss
Interventions
Programming of cochlear implant audio processor frequency settings
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Iowa City, Iowa • Kansas City, Kansas • Chapel Hill, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 23, 2026, 6:15 PM EDT
Recruiting Not applicable Interventional

Single-Sided Deafness and Asymmetric Hearing Loss

NCT04506853
View directory record Official record
Conditions
Hearing Loss, Unilateral, Hearing Loss, Sensorineural
Interventions
MED-EL Cochlear Implant System
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
5 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
5
States / cities
Chicago, Illinois • Iowa City, Iowa • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Jul 23, 2026, 6:15 PM EDT
Recruiting Not applicable Interventional

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

NCT05318417
View directory record Official record
Conditions
Hearing Loss, Unilateral, Deafness, Unilateral
Interventions
The Cochlear™ Nucleus® Cochlear Implant (CI) System
Device
Lead sponsor
Cochlear
Industry
Eligibility
5 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
8
States / cities
Palo Alto, California • Englewood, Colorado • Iowa City, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 23, 2026, 6:15 PM EDT
Terminated Phase 2 Interventional Results available

Study of Tepotinib Combined With Cetuximab in Participants With Left-Sided RAS/BRAF Wild Type Metastatic Colorectal Cancer (PERSPECTIVE)

NCT04515394
View directory record Official record
Conditions
Colorectal Neoplasms
Interventions
Tepotinib, Cetuximab
Drug · Biological
Lead sponsor
EMD Serono Research & Development Institute, Inc.
Industry
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
13
States / cities
Phoenix, Arizona • La Jolla, California • Santa Monica, California + 10 more
Source: ClinicalTrials.gov public record
Updated Dec 21, 2022 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional

Auditory Nerve Test System During Vestibular Schwannoma Resection

NCT04241679
View directory record Official record
Conditions
Vestibular Schwannoma, Acoustic Neuroma, Sensorineural Hearing Loss, Asymmetric Sensorineural Hearing Loss, Cochlear Nerve Damage, Cochlear Nerve Deafness, Skull Base Neoplasms, Auditory; Nerve
Interventions
Auditory Nerve Test System
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 24, 2024 · Synced Jul 23, 2026, 6:15 PM EDT
Not listed No phase listed Observational

SoundBite Hearing System 24 Month Multi Site Patient Use Study

NCT01807559
View directory record Official record
Conditions
Single Sided Deafness, Conductive Hearing Loss
Interventions
SoundBite Hearing System
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
7
States / cities
Phoenix, Arizona • La Jolla, California • Newport Beach, California + 4 more
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Results available

Benefits of the HiResolution Bionic Ear System in Adults With Asymmetric Hearing Loss

NCT02811549
View directory record Official record
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases, Asymmetrical Hearing Loss, Single-Sided Deafness
Interventions
HiResolution Bionic Cochlear Implant
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
2
States / cities
Sarasota, Florida • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Results available

Cochlear Implantation in Cases of Single-Sided Deafness

NCT02203305
View directory record Official record
Conditions
Unilateral Moderate to Profound Hearing Loss, Asymmetric Hearing Loss, Single-Sided Deafness (SSD)
Interventions
Cochlear Implant, Control Group
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 24, 2022 · Synced Jul 23, 2026, 6:15 PM EDT
Not listed Phase 4 Interventional

Evaluation of Benefit for Treatment of Single Sided Deafness (SSD) Between Two Bone Conduction Prosthetic Devices; Osseointegrated Implant Versus Maxilla Anchored Removable Oral Appliance ("SoundBite")

NCT01933386
View directory record Official record
Conditions
Single Sided Deafness
Interventions
SoundBite
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
3
States / cities
Phoenix, Arizona • Novi, Michigan • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 28, 2013 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Clinical Performance of a New Implant System for Bone Conduction Hearing

NCT03086135
View directory record Official record
Conditions
Deafness; Sensoneural Single Sided, Conductive Hearing Loss, Mixed Hearing Loss
Interventions
Osia System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 13, 2021 · Synced Jul 23, 2026, 6:15 PM EDT
Enrolling by invitation Not applicable Interventional

Optimizing Bilateral and Single-sided-deafness Cochlear Implants for Functioning in Complex Auditory Environments

NCT06305039
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Sensorineural, Cochlear Hearing Loss
Interventions
Diagnostic tests of cochlear implant or acoustic hearing function, Targeted aural rehabilitation of the poorer performing ear
Diagnostic Test · Behavioral
Lead sponsor
University of Maryland, College Park
Other
Eligibility
18 Years to 85 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
2
States / cities
Bethesda, Maryland • College Park, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jul 23, 2026, 6:15 PM EDT
Not listed Not applicable Interventional

Cochlear Implants for Adults With Single-sided Deafness

NCT02259192
View directory record Official record
Conditions
Single-sided Deafness
Interventions
MED-EL Maestro Cochlear Implant
Device
Lead sponsor
Robert Shannon
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 19, 2017 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Single-Sided Deafness in the Medicare Population

NCT05250414
View directory record Official record
Conditions
Hearing Loss, Unilateral
Interventions
MED-EL Cochlear Implant System
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
65 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
2
States / cities
Iowa City, Iowa • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 28, 2025 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Results available

Osia 2 Pediatric Expansion Study

NCT05000931
View directory record Official record
Conditions
Mixed Hearing Loss, Single-Sided Deafness, Conductive Hearing Loss
Interventions
Osia 2 System
Device
Lead sponsor
Cochlear
Industry
Eligibility
5 Years to 11 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
7
States / cities
Phoenix, Arizona • Palo Alto, California • San Diego, California + 4 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Jul 23, 2026, 6:15 PM EDT
Recruiting No phase listed Observational

The Sentio System: Post-market Evaluation of Safety and Performance in Adolescents

NCT06844071
View directory record Official record
Conditions
Hearing Loss
Interventions
Not listed
Lead sponsor
Oticon Medical
Industry
Eligibility
12 Years to 18 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Results available

Long Term Safety of the Sonitus SoundBite System

NCT01108406
View directory record Official record
Conditions
Hearing Loss, Unilateral Hearing Loss, Total Unilateral Deafness
Interventions
Sonitus SoundBite System, SoundBite Hearing System
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2014 · Synced Jul 23, 2026, 6:15 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Cochlear Implantation in Children With Asymmetric Hearing Loss or Single-Sided Deafness Clinical Trial

NCT04793412
View directory record Official record
Conditions
Asymmetric Hearing Loss, Single-sided Deafness, Unilateral Deafness
Interventions
Cochlear Implant
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
4 Years to 14 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
5
States / cities
Los Angeles, California • Minneapolis, Minnesota • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jul 23, 2026, 6:15 PM EDT
Completed No phase listed Observational

Single-sided Deafness and Cochlear Implantation

NCT05052944
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Unilateral, Hearing Loss, Sudden, Hearing Loss, Cochlear, Hearing Loss in Left Ear, Hearing Loss in Right Ear, Labyrinthitis
Interventions
Cochlear implantation
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
5
States / cities
Baltimore, Maryland • Bethesda, Maryland • Lutherville-Timonium, Maryland + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 12, 2023 · Synced Jul 23, 2026, 6:15 PM EDT
Completed Not applicable Interventional Results available

Implantation of the Cochlear® Nucleus® System in Adults With Single-Sided Deafness

NCT01670006
View directory record Official record
Conditions
Single Sided Deafness
Interventions
Cochlear Nucleus Cochlear Implant System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Jul 23, 2026, 6:15 PM EDT