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ClinicalTrials.gov public records Last synced Nov 2, 2026, 1:40 AM EST

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Showing 97–120 of 279 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Skeletal Disorders Clear all
Terminated Phase 3 Interventional Results available

Risedronate to Prevent Skeletal Related Events in Patients With Metastatic Prostate Cancer Commencing Hormonal Therapy

NCT00216060
View directory record Official record
Conditions
Metastatic Prostate Cancer
Interventions
Risedronate, Placebo
Drug
Lead sponsor
Christopher Sweeney, MBBS
Other
Eligibility
18 Years and older · Male only
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
31
States / cities
La Mesa, California • San Bernardino, California • New Britain, Connecticut + 26 more
Source: ClinicalTrials.gov public record
Updated May 26, 2016 · Synced Nov 2, 2026, 1:40 AM EST
Terminated Early Phase 1 Interventional

A Pilot Study of Pyridostigmine in Pompe Disease

NCT02357225
View directory record Official record
Conditions
Pompe Disease
Interventions
Pyridostigmine Bromide
Drug
Lead sponsor
University of Florida
Other
Eligibility
8 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Nov 2, 2026, 1:40 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Effects of Chronic Night Shift

NCT05091021
View directory record Official record
Conditions
Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
20 Years to 50 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Synbiotic to Attenuate Resorption of the Skeleton

NCT06389539
View directory record Official record
Conditions
Osteoporosis, Inflammation, Aging
Interventions
SBD111 medical food, Placebo
Other
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
60 Years and older · Female only
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Roslindale, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Multi-Tracer PET Quantitation of Skeletal Muscle Insulin Resistance in Type 2 Diabetes Mellitus

NCT00222781
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
30 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2007 · Synced Nov 2, 2026, 1:40 AM EST
Completed Phase 1 Interventional

A Study to Assess BHQ880 in Combination With Zoledronic Acid in Relapsed or Refractory Myeloma Patients

NCT00741377
View directory record Official record
Conditions
Multiple Myeloma Bone Disease
Interventions
BHQ880, Zoledronic acid
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 78 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
5
States / cities
Scottsdale, Arizona • Fayetteville, Arkansas • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Nov 2, 2026, 1:40 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics

NCT04226131
View directory record Official record
Conditions
Rheumatoid Arthritis, Healthy Controls
Interventions
Blood Draw, Disease Activity (DAS-28) Assessment, Skeletal Muscle Mitochondrial Respiratory Capacity, Muscle Biopsy, Body Composition, Cardiopulmonary Exercise Test (CPET), Strength Testing, Questionnaires, Skeletal Muscle Biomechanical Property Assessment
Other
Lead sponsor
Duke University
Other
Eligibility
25 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Nov 2, 2026, 1:40 AM EST
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse

NCT04151901
View directory record Official record
Conditions
Atrophy of Muscle Due to Disuse, Rehabilitation
Interventions
Resistance Exercise Rehabilitation, Walking-based rehabilitation
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
50 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
2
States / cities
Galveston, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Heat Therapy During Reduced Physical Activity

NCT07847424
View directory record Official record
Conditions
Physical Inactivity, Vascular Dysfunction, Skeletal Muscle Atrophy
Interventions
Sauna, Reduced Physical Activity
Device · Behavioral
Lead sponsor
Brigham Young University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Completed Phase 2 Interventional Results available

A Clinical Trial to Evaluate the Safety and Efficacy of BMN 111 in Infants and Young Children With Achondroplasia

NCT03583697
View directory record Official record
Conditions
Achondroplasia
Interventions
BMN 111, Placebo
Drug
Lead sponsor
BioMarin Pharmaceutical
Industry
Eligibility
Up to 59 Months
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
9
States / cities
Oakland, California • Torrance, California • Wilmington, Delaware + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 13, 2024 · Synced Nov 2, 2026, 1:40 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity

NCT02945410
View directory record Official record
Conditions
Weight Loss, Starvation
Interventions
Caloric Restriction, Protein, Exercise, Calcium and Vitamin D, Maltodextrin
Other · Dietary Supplement
Lead sponsor
University of Nebraska Lincoln
Other
Eligibility
19 Years to 30 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Dec 19, 2019 · Synced Nov 2, 2026, 1:40 AM EST
Completed No phase listed Observational Accepts healthy volunteers Results available

Blood Flow, Muscle Regeneration and Sarcopenia

NCT01035060
View directory record Official record
Conditions
Sarcopenia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 9, 2013 · Synced Nov 2, 2026, 1:40 AM EST
Active, not recruiting No phase listed Observational

Glycemic Control, Type II Diabetes, Parathyroidectomy

NCT05761743
View directory record Official record
Conditions
Primary Hyperparathyroidism, Type 2 Diabetes
Interventions
Urine and Blood Test
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Not listed No phase listed Observational

Measures of Mitochondria Dysfunction in PD

NCT04300608
View directory record Official record
Conditions
Parkinson Disease, Mitochondrial
Interventions
Not listed
Lead sponsor
University of Washington
Other
Eligibility
65 Years to 85 Years
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 5, 2020 · Synced Nov 2, 2026, 1:40 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity

NCT04286451
View directory record Official record
Conditions
Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
Interventions
Sleep Restriction, Habitual Sleep
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Nov 2, 2026, 1:40 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle

NCT01644279
View directory record Official record
Conditions
Sarcopenia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
20 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Nov 2, 2026, 1:40 AM EST
Completed No phase listed Observational

Study of Muscle Abnormalities in Patients With Specific Genetic Mutations

NCT00001871
View directory record Official record
Conditions
Cardiomyopathy, Hypertrophic, Muscular Dystrophy, Oculopharyngeal
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
Not listed
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Nov 2, 2026, 1:40 AM EST
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Power Training Post-stroke

NCT01970592
View directory record Official record
Conditions
Stroke
Interventions
POWER training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2020 · Synced Nov 2, 2026, 1:40 AM EST
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Characterization of Clinical Skeletal and Cardiac Impairment in Carriers of DMD and BMD

NCT02972580
View directory record Official record
Conditions
Duchenne Muscular Dystrophy, Becker Muscular Dystrophy
Interventions
Genetic characterization
Genetic
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2030
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Nov 2, 2026, 1:40 AM EST
Recruiting No phase listed Observational Accepts healthy volunteers

Ethanol Induces Skeletal Muscle Autophagy

NCT03209791
View directory record Official record
Conditions
Alcoholic Liver Disease
Interventions
Biopsies
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Active, not recruiting Phase 4 Interventional

Romosozumab Use to Build Skeletal Integrity

NCT05058976
View directory record Official record
Conditions
Osteoporosis, Osteoporosis, Postmenopausal, Osteoporosis Fracture
Interventions
Romosozumab, Placebo, Zoledronic acid, Calcium and Vitamin D
Drug · Dietary Supplement
Lead sponsor
Susan L. Greenspan
Other
Eligibility
65 Years and older · Female only
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Nov 2, 2026, 1:40 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Diet on the Gut-Muscle Axis in Older Adults

NCT05549622
View directory record Official record
Conditions
Sarcopenia, Dietary Exposure, Microbial Colonization
Interventions
Low-soluble fiber diet, High-soluble fiber diet
Other
Lead sponsor
Tufts University
Other
Eligibility
65 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Nov 2, 2026, 1:40 AM EST
Completed Phase 1 Interventional

Alpharadin™ (Radium-223 Chloride) Safety and Dosimetry With HRPC That Has Metastasized to the Skeleton

NCT00748046
View directory record Official record
Conditions
Prostate Cancer, Metastases, Pharmacokinetics
Interventions
Radium-223 chloride (BAY88-8223)
Drug
Lead sponsor
Bayer
Industry
Eligibility
18 Years and older · Male only
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Nov 2, 2026, 1:40 AM EST
Completed Phase 4 Interventional Results available

Effect of Pioglitazone on TIMP-3 and TACE in Type 2 Diabetes

NCT01223196
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Pioglitazone, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 11, 2016 · Synced Nov 2, 2026, 1:40 AM EST