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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Skeletal Muscle Disorder Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia Elderly

NCT03368872
View directory record Official record
Conditions
Sarcopenia
Interventions
Astaxanthin formulation, Placebo, Exercise training
Other
Lead sponsor
Astavita, Inc.
Industry
Eligibility
65 Years to 85 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 10, 2017 · Synced Sep 23, 2026, 3:26 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

NIRS to Diagnose SAMS

NCT03653663
View directory record Official record
Conditions
Statin Adverse Reaction, Skeletal Myopathy
Interventions
Simvastatin 20 mg, Placebo Oral Tablet
Drug
Lead sponsor
Hartford Hospital
Other
Eligibility
40 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
2
States / cities
Hartford, Connecticut • Storrs, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 12, 2020 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational

Investigating Bone and Skeletal Muscle Interaction in Men With Prostate Cancer

NCT03386812
View directory record Official record
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years to 89 Years · Male only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jan 14, 2021 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multi-Tracer PET Quantitation of Insulin Action in Muscle (Phase 1, Phase 2, Phase 3, Phase 4)

NCT00222885
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
20 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 18, 2007 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Physical Activity in Overweight Girls: Implications for Reversing Risk Factors for Type 2 Diabetes

NCT01323088
View directory record Official record
Conditions
Abdominal Obesity, Physical Activity
Interventions
Control, Resistance Exercise, Aerobic exercise
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
12 Years to 18 Years · Female only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 14, 2013 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional Results available

Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

NCT02739620
View directory record Official record
Conditions
Breast Cancer
Interventions
Neuromuscular electrical stimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 10, 2023 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional

Effects of Epicatechin on Functional Capacity, Skeletal Muscle Structure and Diastolic Function in Patients With Heart Failure With Preserved Ejection Fraction (HFPEF)

NCT02068040
View directory record Official record
Conditions
Heart Failure
Interventions
CocoaVia
Dietary Supplement
Lead sponsor
University of California, San Diego
Other
Eligibility
40 Years to 60 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2015 · Synced Sep 23, 2026, 3:26 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Graded Protein Intake on Body Composition in Older Adults

NCT04845282
View directory record Official record
Conditions
Sarcopenia
Interventions
Graded Protein plus Resistance Training, RDA Protein plus Resistance Training
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
55 Years to 110 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2022 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Phase 4 Interventional Results available

Effect of Prolonged PDE-5 Inhibition on Insulin Signaling in Skeletal Muscle.

NCT02129725
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Sildenafil citrate, Placebo Oral Capsule
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 18, 2017 · Synced Sep 23, 2026, 3:26 AM EDT
Not yet recruiting Not applicable Interventional

The Effect of Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation on Bone Strength.

NCT07325149
View directory record Official record
Conditions
Secondary Osteoporosis, Sarcopenia
Interventions
Exoskeleton-Assisted Walking (EAW) + active Transcutaneous Spinal Cord Stimulation (tSCS), Exoskeleton-assisted walking (EAW) + sham Transcutaneous Spinal Cord Stimulation (tSCS)
Device
Lead sponsor
Bronx VA Medical Center
Federal
Eligibility
21 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2033
U.S. locations
1
States / cities
West Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational

Skeletal Muscle Health in Children With Type 1 Diabetes

NCT04288063
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
6 Years to 11 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 10, 2023 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of PrimaVie and Exercise Training on Human Skeletal Muscle (PrimaVie)

NCT02026414
View directory record Official record
Conditions
Obesity
Interventions
PrimaVie, Exercise
Dietary Supplement · Other
Lead sponsor
Sanni Raju
Industry
Eligibility
21 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health

NCT02066948
View directory record Official record
Conditions
Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
Interventions
wt loss, meal pattern, even, skew
Other · Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
19 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational

Effects of Aromatase Inhibitor Therapy on Muscle Function

NCT03581552
View directory record Official record
Conditions
Breast Cancer, Breast Cancer Female
Interventions
Not listed
Lead sponsor
Tarah J Ballinger, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 9, 2021 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

SPECT/CT Imaging of Skeletal Muscle Perfusion

NCT02791204
View directory record Official record
Conditions
Peripheral Arterial Disease, Diabetes Mellitus
Interventions
SPECT/CT imaging following revascularization procedures, SPECT/CT imaging
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2026
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 23, 2026, 3:26 AM EDT
Recruiting Phase 4 Interventional

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

NCT05183126
View directory record Official record
Conditions
Breast Cancer, Metastatic Gastric Cancer, Esophageal Cancer
Interventions
Paclitaxel
Drug
Lead sponsor
University of Michigan Rogel Cancer Center
Other
Eligibility
18 Years and older · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational

Pilot Study of Strength Testing in Overweight Women With or Without Insulin Resistance

NCT01862757
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Sep 23, 2026, 3:26 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Ceramides in Muscle During Insulin Resistance

NCT03731598
View directory record Official record
Conditions
Insulin Resistance
Interventions
bed rest
Procedure
Lead sponsor
University of Utah
Other
Eligibility
60 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 21, 2022 · Synced Sep 23, 2026, 3:26 AM EDT
Recruiting Not applicable Interventional

Heat and Exercise in Aging as Therapy (HEAT)

NCT06580964
View directory record Official record
Conditions
Prediabetic State
Interventions
Heat therapy, High-intensity interval training
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
50 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Sep 23, 2026, 3:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

PET/CT of Skeletal Muscle Amino Acid Kinetics

NCT01698424
View directory record Official record
Conditions
Sarcopenia
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years to 80 Years · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2015 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

NCT01856868
View directory record Official record
Conditions
Becker Muscular Dystrophy
Interventions
(-)-epicatechin
Drug
Lead sponsor
Craig McDonald, MD
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 21, 2021 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Supplementation of Glutamine and Fish Oil Versus Placebo in Patients With Heart Failure

NCT01534663
View directory record Official record
Conditions
Heart Failure
Interventions
Glutamine and Fish Oil Supplementation, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
35 Years to 80 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 21, 2020 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity

NCT04286451
View directory record Official record
Conditions
Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
Interventions
Sleep Restriction, Habitual Sleep
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
Female only
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Sep 23, 2026, 3:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of High Fat Diet on Muscle Metabolism

NCT02328235
View directory record Official record
Conditions
Diabetes
Interventions
High Saturated Fat Diet
Other
Lead sponsor
Kevin Davy
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Sep 23, 2026, 3:26 AM EDT