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ClinicalTrials.gov public records Last synced Oct 20, 2026, 4:09 PM EDT

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Showing 1–24 of 71 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Skin Appearance Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Effectiveness of a Novel Dietary Ingredient on Hair Growth and Skin's Appearance

NCT06010745
View directory record Official record
Conditions
Hair Thinning, Facial Skin Texture, Skin Ageing
Interventions
Biotin and silicon, Placebo
Dietary Supplement
Lead sponsor
Nutrition 21, Inc.
Industry
Eligibility
35 Years to 70 Years
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 25, 2023 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Phase 4 Interventional Results available

A Study to Assess the Adverse Events and Effectiveness of Rapid Acoustic Pulse (RAP) Device for the Appearance of Cellulite in Adult Participants

NCT05664581
View directory record Official record
Conditions
Cellulite
Interventions
Rapid Acoustic Pulse
Device
Lead sponsor
Zeltiq Aesthetics
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Pleasanton, California
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery

NCT04554316
View directory record Official record
Conditions
Scar, Breast Neoplasms, Breast Diseases, Surgical Wound
Interventions
Steri-strip
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
94 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
2
States / cities
East Norriton, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Proof of Concept Study to Isolate Cosmetic Improvement of Skin Using the Vitro Biopharma Secretome/Exosome Serum

NCT07620158
View directory record Official record
Conditions
Cosmetic Effect
Interventions
Secretome/Exosome Serum
Other
Lead sponsor
Vitro Biopharma Inc.
Industry
Eligibility
30 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 20, 2026, 4:09 PM EDT
Terminated Not applicable Interventional Results available

An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity

NCT06941610
View directory record Official record
Conditions
Skin Laxity
Interventions
Erchonia GVS Laser
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
22 Years to 70 Years
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Dunedin, Florida
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combination Versus Laser Treatment Only

NCT03661697
View directory record Official record
Conditions
Photoaging
Interventions
Laser Therapy, Basic Skin Care Regimen, Lytera
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 24, 2020 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Clinical Trial to Evaluate the Effects of Cowboy Colostrum on Gut Health, Body Composition, Hair Growth, and Skin Appearance

NCT07756866
View directory record Official record
Conditions
Gut Health, Body Composition, Hair Growth, Skin Appearance, Healthy Weight Management, Gastrointestinal Health
Interventions
Cowboy Colostrum
Dietary Supplement
Lead sponsor
Cowboy Colostrum
Industry
Eligibility
21 Years to 47 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Phase 2 Interventional

High-resolution Magnetic Resonance Imaging (MRI) Scans to Look for Spread of Melanoma to Nearby Lymph Nodes

NCT00463892
View directory record Official record
Conditions
Melanoma
Interventions
High-resolution contrast-enhanced MRI scan
Procedure
Lead sponsor
Redwood Regional Medical Group
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Sebastopol, California
Source: ClinicalTrials.gov public record
Updated Nov 11, 2014 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

An Investigation of the Effects of a Skin Serum Containing Propolis on Skin Health and Appearance

NCT06148740
View directory record Official record
Conditions
Skin Health
Interventions
Manuka Health Pro Vitality Daily Restorative Face Serum with Propolis & Vitamin C
Other
Lead sponsor
Manuka Health
Industry
Eligibility
30 Years to 42 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2024 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional

The Effect of Topical Almond Oil vs. Topical Retinol on The Appearance of Facial Wrinkles

NCT05011461
View directory record Official record
Conditions
Wrinkles, Skin
Interventions
Almond Oil
Other
Lead sponsor
University of California, Davis
Other
Eligibility
40 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety Study of AZT-04 for Cosmetic Use

NCT03820076
View directory record Official record
Conditions
Study of Three Doses of AZT-04 for Skin Appearance
Interventions
AZT-04
Other
Lead sponsor
Azitra Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Irving, Texas
Source: ClinicalTrials.gov public record
Updated Jul 9, 2020 · Synced Oct 20, 2026, 4:09 PM EDT
Not yet recruiting No phase listed Observational Accepts healthy volunteers

Comparing Facial Aging Between Identical Twins With 3D Imaging

NCT07760532
View directory record Official record
Conditions
Facial Skin Aging, Facial Volume Loss, Wrinkle Appearance
Interventions
GLP-1 Receptor Agonists
Drug
Lead sponsor
Ponsky Facial Aesthetics And Plastic Surgery, Llc
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Beachwood, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 20, 2026, 4:09 PM EDT
Completed No phase listed Observational

An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection

NCT05202366
View directory record Official record
Conditions
Fungal Infection, Onychomycosis, Tinea Unguium
Interventions
CGB-400 Topical Gel
Drug
Lead sponsor
CAGE Bio Inc.
Industry
Eligibility
18 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Study to Evaluate the Safety and Effectiveness of the RAP Device for the Improvement in the Appearance of Cellulite

NCT05199506
View directory record Official record
Conditions
Cellulite
Interventions
RAP
Device
Lead sponsor
Soliton
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 20, 2026, 4:09 PM EDT
Completed No phase listed Observational

An Evaluation of the Cosmetic Appearance of Metronidazole Gel (MetroGel®) 1%

NCT00668655
View directory record Official record
Conditions
Rosacea
Interventions
Metronidazole Gel
Drug
Lead sponsor
Galderma R&D
Industry
Eligibility
20 Years to 75 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
High Point, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 29, 2022 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lumenato Nutritional Supplement on Skin Appearance

NCT04248699
View directory record Official record
Conditions
Skin
Interventions
Lumenato
Dietary Supplement
Lead sponsor
LycoRed Ltd.
Industry
Eligibility
35 Years to 55 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Aug 18, 2020 · Synced Oct 20, 2026, 4:09 PM EDT
Not listed Not applicable Interventional

A Clinical Trial to Examine the Efficacy of a Dietary Supplement to Improve the Health and Appearance of Hair.

NCT06515496
View directory record Official record
Conditions
Hair Thinning, Hair Shedding
Interventions
Scale HLV Clinical Formula Hair Vitamins, Placebo
Dietary Supplement · Other
Lead sponsor
Scale Media Inc
Industry
Eligibility
35 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2024 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Phase 1 Interventional

1320 nm Nd:YAG Laser for Improving the Appearance of Onychomycosis

NCT01498393
View directory record Official record
Conditions
Fungal Nail Infection
Interventions
Laser treatment
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Phase 4 Interventional

Evaluating Skin Appearance Following 5-Flourouracil Cream for Treatment of Actinic Keratosis and the Effects of Topical Agents

NCT03279328
View directory record Official record
Conditions
Actinic Keratoses
Interventions
Topical Steroid Ointment, Vaseline, Skin Barrier Moisturier
Drug · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 25, 2019 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Phase 4 Interventional Results available

A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers

NCT01143714
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Santyl, White Petrolatum
Drug · Other
Lead sponsor
Healthpoint
Industry
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
6
States / cities
Sylmar, California • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated May 6, 2013 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Phase 4 Interventional Results available

Study to Assess DerMend Moisturizing Bruise Formula in Improving the Appearance of Chronically Aged Forearms and Hands

NCT01910831
View directory record Official record
Conditions
Purpura
Interventions
DerMend Moisturizing Bruise Formula, Non-active placebo control
Drug
Lead sponsor
The Center for Clinical and Cosmetic Research
Other
Eligibility
60 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated Dec 2, 2019 · Synced Oct 20, 2026, 4:09 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of SPM™ Topical Cosmetic Application on Skin Appearance, Hydration, and Barrier Support in Healthy Adults

NCT07236736
View directory record Official record
Conditions
Healthy Skin, Skin Hydration
Interventions
Skin biopsy, Corneometer® Measurement, Tewameter® Measurement
Procedure · Other
Lead sponsor
Biocoz Global Pte. Ltd.
Industry
Eligibility
20 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2028
U.S. locations
1
States / cities
West Hollywood, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 20, 2026, 4:09 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of the Effect of Low Level Laser Light Therapy on Reducing the Appearance of Cellulite in the Thighs and Buttocks.

NCT01702259
View directory record Official record
Conditions
Cellulite
Interventions
Erchonia Scanner device (GLS), Placebo device
Device
Lead sponsor
Erchonia Corporation
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
2
States / cities
Marion, Indiana • Bloomfield Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 11, 2015 · Synced Oct 20, 2026, 4:09 PM EDT
Recruiting No phase listed Observational

Outcomes Associated With Tirbanibulin for Large Field Application on the Face in the U.S (CLEAR)

NCT07657988
View directory record Official record
Conditions
Actinic Keratosis (AK)
Interventions
Tirbanibulin
Drug
Lead sponsor
Avant Health LLC
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Manhattan Beach, California • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 20, 2026, 4:09 PM EDT