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Showing 1–24 of 28 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Skin Rejuvenation Clear all
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Evaluation of SofWave Sofware-Guided Energy Delivery for Lower Face and Neck Rejuvenation

NCT07723664
View directory record Official record
Conditions
Facial Wrinkles, Jawline Contour, Skin Laxity
Interventions
SofWave
Device
Lead sponsor
Sofwave Medical LTD
Industry
Eligibility
40 Years to 55 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 26, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Novel Laser for Skin Rejuvenation

NCT02910492
View directory record Official record
Conditions
Rejuvenation
Interventions
enLighten Laser
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
2
States / cities
Brisbane, California • Stamford, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 14, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Dermal Rejuvenation on the UVB Response of Geriatric Skin

NCT02090894
View directory record Official record
Conditions
Pre-cancerous Geriatric Skin
Interventions
UV Light (Laser Genesis)
Device
Lead sponsor
Indiana University
Other
Eligibility
65 Years to 99 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Oct 10, 2018 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation

NCT06366503
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer, Sunscreen, Basic Ointment
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Blue Ash, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Single-Center Open-Label Study of 1064 nm for Nonablative Skin Rejuvenation

NCT03421691
View directory record Official record
Conditions
Skin Pigment, Photoaging
Interventions
excel V Laser
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
35 Years to 55 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 5, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

TCA 15% Chemical Peel for Improvement in Hand Lentigines

NCT05471947
View directory record Official record
Conditions
Photoaging, Lentigo
Interventions
15% Trichloroacetic acid + 3% glycolic acid
Drug
Lead sponsor
Main Line Center for Laser Surgery
Other
Eligibility
22 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Ardmore, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Straberi Epistamp Needling Treatment For Skin Rejuvenation

NCT04742803
View directory record Official record
Conditions
Wrinkle, Elastic Skin, Collagen Degeneration
Interventions
Straberi Epistamp Microneedling Treatment
Device
Lead sponsor
Universal Skincare Institute
Other
Eligibility
21 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Characterization of Skin and Facial Fat Pad Thickness Changes Following Microneedling Radiofrequency With and Without Topical Poly-L-Lactic Acid for Facial Rejuvenation

NCT07261527
View directory record Official record
Conditions
Skin Texture
Interventions
microneedling RF treatment, PLLA, Sterile Water as control
Device · Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Safety and Efficacy of Micro-coring Device for Treatment of Facial Wrinkles and Skin Laxity

NCT03228641
View directory record Official record
Conditions
Wrinkle, Facial and Neck Skin Laxity
Interventions
micro-excisional skin removal with coring needle
Device
Lead sponsor
Cytrellis Biosystems, Inc.
Industry
Eligibility
40 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
6
States / cities
Sacramento, California • Miami, Florida • Chestnut Hill, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Altreno for Chest Rejuvenation

NCT04096742
View directory record Official record
Conditions
Photodamaged Skin, Photoaging
Interventions
tretinoin 0.05% lotion (Altreno), Vehicle
Drug · Other
Lead sponsor
Goldman, Butterwick, Fitzpatrick and Groff
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 1, 2021 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Platelet-rich Fibrin Matrix on Skin Rejuvenation

NCT04128046
View directory record Official record
Conditions
Skin Rejuvenation, Skin Quality, Wrinkle, Nasolabial Fold
Interventions
PRFM injection, Saline injection
Procedure
Lead sponsor
New York Medical College
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Valhalla, New York
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Energy-Based Lower Eyelid Rejuvenation - Proof of Concept for InMode AccuTite With or Without Morpheus8

NCT04103619
View directory record Official record
Conditions
Periorbital Edema
Interventions
AccuTite, AccuTite + Morpheus 8
Device
Lead sponsor
InMode MD Ltd.
Industry
Eligibility
29 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Sarasota, Florida • Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 9, 2022 · Synced Sep 9, 2026, 8:47 PM EDT
Recruiting Not applicable Interventional

Mechanisms for Laser-Induced Rejuvenation

NCT06489301
View directory record Official record
Conditions
Skin Cancer
Interventions
Fractionated Laser Resurfacing
Device
Lead sponsor
Wright State University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Fairborn, Ohio
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional

Comparison of the RevLite Electro-optic Q-Switched Neodymium-doped Yttrium Aluminium Garnet (EO QS Nd:YAG) Laser to a Fractionated Laser System

NCT00955461
View directory record Official record
Conditions
Photodamage, Irregular Pigmentation, Acne Scars
Interventions
RevLite laser treatment, Fractionated Laser treatment
Procedure
Lead sponsor
ConBio, a Cynosure Company
Industry
Eligibility
25 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 27, 2012 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Enhancing Skin Rejuvenation Using Laser and Exosomes

NCT07281690
View directory record Official record
Conditions
Laser Therapy, Exosomes
Interventions
1064-nm Nd:YAG Laser Treatment, Topical Umbilical Cord-Derived Exosomes (UC-MSC Exosomes)
Device · Biological
Lead sponsor
Laser Beamer Skincare
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Wichita, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments

NCT02551562
View directory record Official record
Conditions
Subjects Requesting and Requiring Facial Rejuvenation With Neurotoxins and/or Hyaluronic Acid Fillers
Interventions
NuDerm® System, Placebo
Other
Lead sponsor
DeNova Research
Other
Eligibility
25 Years to 60 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 7, 2019 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of a Novel Microlens Array Device for Skin Rejuvenation

NCT02888626
View directory record Official record
Conditions
Wrinkles, Scars
Interventions
Microlens Array
Device
Lead sponsor
Cutera Inc.
Industry
Eligibility
20 Years to 75 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Brisbane, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Efficacy of the Alma Hybrid System for a New Approach of Facial Skin Treatment

NCT04640207
View directory record Official record
Conditions
Rejuvenation
Interventions
Facial skin treatment
Device
Lead sponsor
Alma Lasers
Industry
Eligibility
35 Years to 60 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Plymouth Meeting, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2021 · Synced Sep 9, 2026, 8:47 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Fractional Photothermolysis for Hair Follicle Induction

NCT03382184
View directory record Official record
Conditions
Alopecia
Interventions
Fraxel Dual laser, Halo laser
Device
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 90 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of the Efficacy and Safety of PiQo4 for Facial Skin Rejuvenation

NCT03322475
View directory record Official record
Conditions
Skin Rejuvenation
Interventions
PiQo4 laser system
Device
Lead sponsor
Focus Medical, LLC
Industry
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2019 · Synced Sep 9, 2026, 8:47 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation

NCT02468453
View directory record Official record
Conditions
Vascular Lesions, Photoaging
Interventions
velos
Device
Lead sponsor
Syneron Medical
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
4
States / cities
San Diego, California • Wayland, Massachusetts • Edina, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2018 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Case Study Evaluating the Efficacy and Tolerability of a Topical Facial Treatment on Healthy Females with Fitzpatrick Skin Types V and VI

NCT06633731
View directory record Official record
Conditions
Skin Smoothness, Radiance, Overall Appearance
Interventions
Biocellulose Mask, Post Procedure Cream, Gentle Cleanser, Facial Moisturizer, sunscreen
Other
Lead sponsor
Revision Skincare
Industry
Eligibility
45 Years to 65 Years · Female only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Sep 9, 2026, 8:47 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation

NCT06436261
View directory record Official record
Conditions
Photoaging, Wrinkle, Skin Laxity
Interventions
Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer, Sunscreen
Procedure · Other
Lead sponsor
Revision Skincare
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Atlanta, Georgia • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Sep 9, 2026, 8:47 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Allograft Adipose Matrix (AAM) in Subcutaneous Dorsal Wrist

NCT02445118
View directory record Official record
Conditions
Aesthetic Rejuvenation
Interventions
Adipose Allograft Matrix (AAM) injection
Other
Lead sponsor
Musculoskeletal Transplant Foundation
Other
Eligibility
35 Years to 75 Years · Female only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Key Biscayne, Florida • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 9, 2016 · Synced Sep 9, 2026, 8:47 PM EDT