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ClinicalTrials.gov public records Last synced Oct 20, 2026, 3:07 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 433–456 of 3,839 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Clear all
Withdrawn Phase 2 Interventional Accepts healthy volunteers

Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau

NCT05728736
View directory record Official record
Conditions
Alzheimer Disease
Interventions
Lemborexant 25 mg, Placebo
Drug
Lead sponsor
Brendan Lucey
Other
Eligibility
60 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial to Evaluate Magtein in Older Adults

NCT02363634
View directory record Official record
Conditions
Mood, Anxiety
Interventions
magnesium threonate
Dietary Supplement
Lead sponsor
Miami Research Associates
Network
Eligibility
45 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2015 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

A Double-Blind, Randomized, Placebo-Controlled Study of the Safety and Effects of CBN With and Without CBD on Sleep Quality

NCT05839964
View directory record Official record
Conditions
Healthy Adults
Interventions
CBN and CBD
Dietary Supplement
Lead sponsor
Canopy Growth Corporation
Industry
Eligibility
18 Years to 55 Years
Enrollment
301 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Fayetteville, Arkansas
Source: ClinicalTrials.gov public record
Updated May 3, 2023 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Not applicable Interventional Results available

LAGB as a Treatment for Morbid Obesity in Adolescents

NCT01045499
View directory record Official record
Conditions
Morbid Obesity, Obstructive Sleep Apnea Syndrome, Metabolic Syndrome, Insulin Resistance, Nonalcoholic Fatty Liver Disease
Interventions
Laparoscopic adjustable gastric banding (Allergan Lap Band)
Device
Lead sponsor
Jeffrey L Zitsman, MD
Other
Eligibility
13 Years to 19 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Oct 20, 2026, 3:07 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Auditory Stimulation on Sleep and Memory in Schizophrenia

NCT04783571
View directory record Official record
Conditions
Schizophrenia
Interventions
Placebo, Auditory Stimulation
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 50 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Completed No phase listed Observational

Underlying Mechanisms of Obesity-induced Obstructive Sleep Apnea

NCT04793334
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity
Interventions
sleeve gastectomy
Procedure
Lead sponsor
Brandon Nokes
Other
Eligibility
18 Years to 65 Years
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Feb 27, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Completed No phase listed Observational

Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents

NCT00222963
View directory record Official record
Conditions
Obesity, Obstructive Sleep Apnea Syndrome
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
8 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2004
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Feb 13, 2009 · Synced Oct 20, 2026, 3:07 PM EDT
Not yet recruiting Not applicable Interventional

The Impact of Brief Behavioral Treatment for Insomnia Versus Brief Mindfulness Treatment on Cognition and Sleep Health in Adults (Age 50+) With HIV

NCT07272863
View directory record Official record
Conditions
Insomnia, Cognition, Aging, HIV
Interventions
BBTI, BMT
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
50 Years to 99 Years
Enrollment
214 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Birmingham, Alabama • Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Use of Multiple Sensors to Track Sleep in Nightshift Workers

NCT06670287
View directory record Official record
Conditions
Sleep, Nightshift Work
Interventions
Single-Sensor Tracking (In-Lab), Multi-Sensor Sleep Tracking (In-Lab), Multi-Sensor Sleep Tracking (At-Home)
Other
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Impact of Smoking Cessation on Sleep - 5

NCT00132821
View directory record Official record
Conditions
Tobacco Use Cessation, Sleep Disorders
Interventions
Bupropion, Transdermal Nicotine Patch, Placebo Bupropion, Placebo transdermal nicotine patch
Drug
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Menlo Park, California
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Chronic Moderate Sleep Restriction in Older Adults

NCT01642719
View directory record Official record
Conditions
Sleep Disturbance, Aging
Interventions
Sleep restriction, Non-sleep restriction
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
4
States / cities
Tucson, Arizona • Los Angeles, California • Brooklyn, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 18, 2019 · Synced Oct 20, 2026, 3:07 PM EDT
Recruiting Phase 3 Interventional

Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea

NCT07332442
View directory record Official record
Conditions
Sleep Apnea, Obstructive Sleep Apnea
Interventions
Eszopiclone, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
North Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Restriction and Postprandial Lipemia

NCT05713370
View directory record Official record
Conditions
Sleep Deprivation, Obesity
Interventions
high fat meal
Dietary Supplement
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
21 Years to 45 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Oct 20, 2026, 3:07 PM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Effect of Melatonin on Sleep Patterns of Resident Trainees During Night Float Shift

NCT05701969
View directory record Official record
Conditions
Sleep Disorders, Circadian Rhythm
Interventions
Melatonin, Placebo
Dietary Supplement · Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Not applicable Interventional

Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing

NCT00004569
View directory record Official record
Conditions
Sleep-Disordered Breathing
Interventions
Non-invasive technique to diagnose and quantitate sleep-disordered breathing
Procedure
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 20, 2026, 3:07 PM EDT
Not yet recruiting Not applicable Interventional

Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA).

NCT07613281
View directory record Official record
Conditions
Snoring, OSA - Obstructive Sleep Apnea
Interventions
Palatal Implant System
Device
Lead sponsor
Serene Sleep, Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
San Francisco, California • Evans, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Recruiting Not applicable Interventional

Brief Sleep Intervention for Bedtime Resistance

NCT06970392
View directory record Official record
Conditions
Child Sleep
Interventions
Bedtime Pass
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Not listed Phase 3 Interventional

Evaluating the Effects of Tasimelteon in Individuals With Autism Spectrum Disorder (ASD) and Sleep Disturbances

NCT05361707
View directory record Official record
Conditions
Autism Spectrum Disorder, Sleep Disorder, Neurological Disorder, Sleep Disturbance
Interventions
Tasimelteon Oral Capsule, Tasimelteon Liquid Suspension
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
2 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
5
States / cities
San Jose, California • San Leandro, California • Santa Monica, California + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Phase 2 Interventional

A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia

NCT01277107
View directory record Official record
Conditions
Insomnia
Interventions
Zaleplon AP formulation, Placebo capsule
Drug
Lead sponsor
Intec Pharma Ltd.
Industry
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
5
States / cities
San Diego, California • Miami, Florida • Pembroke Pines, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Phase 2Phase 3 Interventional

RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA

NCT06146101
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
IHL-42X Low Dose, IHL-42X High Dose, Placebo, IHL-42X (Optimal Dose), Dronabinol, Acetazolamide
Drug
Lead sponsor
Incannex Healthcare Ltd
Industry
Eligibility
18 Years and older
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
20
States / cities
Chula Vista, California • Long Beach, California • Upland, California + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Completed Not applicable Interventional

Sleep Intervention for Youth With Type 1 Diabetes

NCT01739712
View directory record Official record
Conditions
Diabetes
Interventions
Sleep extension, Fixed Sleep Duration
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
10 Years to 16 Years
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 21, 2016 · Synced Oct 20, 2026, 3:07 PM EDT
Enrolling by invitation Not applicable Interventional

Clinician Supported Mobile App to Reduce Mental Health Symptoms Among World Trade Center Responders in Florida

NCT06648928
View directory record Official record
Conditions
PTSD Symptoms, Anxiety Symptoms, Depression Symptoms, Sleep Disturbance
Interventions
Clinician Supported PTSD Coach, Self Managed PTSD Coach
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
Not listed
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 20, 2026, 3:07 PM EDT
Terminated Not applicable Interventional

Effects of Nocturnal Nasal Oxygen on Biomarkers in Sleep Apnea Patients With Heart Failure

NCT01431157
View directory record Official record
Conditions
Sleep Apnea, Heart Failure
Interventions
Nocturnal nasal oxygen, No nasal oxygen
Procedure · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Oct 20, 2026, 3:07 PM EDT
Enrolling by invitation Not applicable Interventional

SHADES Mechanistic Trial

NCT06041581
View directory record Official record
Conditions
Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance, Sleep Disorder, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke, Autonomic Dysfunction, Systemic Inflammatory Response, Metabolic Disease
Interventions
Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I, Active Control: Sleep Education/Hygiene, Symptom Monitoring, and Usual Primary Care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 20, 2026, 3:07 PM EDT