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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Sleep Deprivation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Snooze Control: Sleep Duration & Glucose Metabolism

NCT02583750
View directory record Official record
Conditions
Glucose Metabolism Disorders
Interventions
OGTT after deprived sleep first, OGTT after sufficient sleep first
Behavioral
Lead sponsor
Xuewen Wang
Other
Eligibility
18 Years to 25 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2015 · Synced Jul 21, 2026, 6:45 AM EDT
Terminated Not applicable Interventional

Chronotherapy Randomized Controlled Trial

NCT02176824
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Depression, Suicidal Ideation
Interventions
Total Sleep deprivation, Sleep Phase Advance, and Bright Light Therapy, Partial Sleep deprivation, Sleep Phase Delay, and Low amber light., Treatment as usual
Behavioral · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 90 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 29, 2019 · Synced Jul 21, 2026, 6:45 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Effect of Sleep Deprivation on Cognitive Function Among Cardiology Fellows

NCT05513339
View directory record Official record
Conditions
Wellness, Burnout, Sleep Deprivation, Executive Function
Interventions
WHOOP strap 4.0
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 99 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2022 · Synced Jul 21, 2026, 6:45 AM EDT
Recruiting Phase 1Phase 2 Interventional

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

NCT06226077
View directory record Official record
Conditions
Obesity, Insufficient Sleep
Interventions
sleep extension intervention, contact control intervention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 75 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

White Noise to Improve Sleep in the Medical Intensive Care Unit (MICU): a Pilot and Feasibility Study

NCT03755011
View directory record Official record
Conditions
Sleep Deprivation
Interventions
white noise, usual care
Device · Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 31, 2019 · Synced Jul 21, 2026, 6:45 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Caffeine Optimization Versus Standard Caffeine Dosage (2B-2)

NCT05588934
View directory record Official record
Conditions
Sleep Deprivation, Caffeine
Interventions
Caffeine Gum, Placebo Gum
Dietary Supplement · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 39 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Loss and Energy Metabolism in People With Family History of Type 2 Diabetes.

NCT00724087
View directory record Official record
Conditions
Sleep, Sleep Deprivation, Insulin Resistance, Type 2 Diabetes
Interventions
5.5-hour bedtime, 8.5-hour bedtime
Other
Lead sponsor
University of Chicago
Other
Eligibility
21 Years to 40 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 4, 2013 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Location-based Smartphone Technology to Guide College Students Healthy Choices Ph II

NCT02996864
View directory record Official record
Conditions
Overweight and Obesity, Health Behavior, Sleep Deprivation
Interventions
Healthy Detours App, Fat Secret App
Other
Lead sponsor
Klein Buendel, Inc.
Industry
Eligibility
18 Years to 29 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
2
States / cities
Golden, Colorado • Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Feb 5, 2023 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Examining the Differential Effects of Traditional Float-REST and Dry Float on Subjective and Objective Health Outcomes

NCT04628910
View directory record Official record
Conditions
Sleep Quality
Interventions
Simulated Flotation Therapy, Traditional Float-REST Therapy
Other
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 60 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Aug 27, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep & Stress in Healthcare Providers After Defined Music Intervention Measure by 7-Tesla fMRI & Actigraphy

NCT05980429
View directory record Official record
Conditions
Stress, Psychological, Burnout, Professional, Sleep Deprivation, Music Therapy
Interventions
Music Therapy, prescribed, Music Therapy, self-selected
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
30 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 14, 2024 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mobile Apps for Preschool Parents (MAPP) Study

NCT06520072
View directory record Official record
Conditions
Obesity, Childhood, Nutrition, Healthy, Physical Inactivity, Sleep, Inadequate
Interventions
Children Eating Well (CHEW) mobile app, Beanstalk mobile app
Behavioral
Lead sponsor
Pamela Hull
Other
Eligibility
18 Years to 99 Years
Enrollment
224 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 21, 2026, 6:45 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Improving Metabolic & Mental Health in Female Healthcare Shift Workers

NCT06158204
View directory record Official record
Conditions
Sleep, Inadequate, Overweight and Obesity, Work Related Stress, Healthy Lifestyle
Interventions
Lifestyle Intervention
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity

NCT06784544
View directory record Official record
Conditions
Sleep, Inadequate, Energy Deficit, Iron Absorption, High Physical Activity
Interventions
Operational Stressors
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
17 Years to 39 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 19, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Home Sleep and Circadian Phase: Mediators of Diabetes Risk

NCT01786564
View directory record Official record
Conditions
Sleep Deprivation, Diabetes, Circadian Dysregulation
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
21 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 26, 2020 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients

NCT00581009
View directory record Official record
Conditions
Major Depressive Disorder, Bipolar Disorder
Interventions
chronobiological augmentation, sertraline, lithium, one night of sleep deprivation and two FDG PET scans
Other · Drug · Radiation
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2011
U.S. locations
2
States / cities
Irvine, California • La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2024 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Results available

Triple Vulnerability? Circadian Tendency, Sleep Deprivation and Adolescence

NCT01828320
View directory record Official record
Conditions
Eveningness/Sleep
Interventions
Cognitive Behavior Therapy for Insomnia, Interpersonal and Social Rhythms Therapy, Chronotherapy, Psychoeducation
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
10 Years to 18 Years
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Recovery Protein Nutrition as a Countermeasure for Anabolic Resistance Following Sleep Loss

NCT06073080
View directory record Official record
Conditions
Sleep, Inadequate
Interventions
Protein Nutrition During Recovery
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Jul 21, 2026, 6:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Work Schedule and Sleep Patterns on Caregivers' Health

NCT01443156
View directory record Official record
Conditions
Obesity, Diabetes, Cancer, Metabolic Syndrome, Sleep Deprivation
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
211 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Bend, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 1, 2023 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Results available

A Study of the Effectiveness and Efficacy of the PowerSleep Device

NCT03162328
View directory record Official record
Conditions
Sleep Deprivation, Insufficient Sleep Syndrome, Healthy
Interventions
PowerSleep Stim, PowerSleep Sham
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 50 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
7
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Lehigh Acres, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2021 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Outcomes for Patients With SDB and Insufficient Sleep

NCT04279834
View directory record Official record
Conditions
Sleep Apnea, Insufficient Sleep Syndrome, Sleep, Hypertension
Interventions
PAP Treatment, Sleep Education I
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
558 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2025
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Jul 21, 2026, 6:45 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

NCT02758990
View directory record Official record
Conditions
Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds, Dyspnea, Headache, Migraine Disorders, Arthritis, Arthralgia, Anxiety, Sleep Initiation and Maintenance Disorders, Sleep Deprivation
Interventions
Vitamin A, Vitamin B6, Vitamin C, Nicotinamide, Vitamin D3, Vitamin E, Broccoli, Spinach, Caffeine, Coffee, Axon Eyewear, Chocolate
Dietary Supplement · Other · Device
Lead sponsor
Verifomics LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2017 · Synced Jul 21, 2026, 6:45 AM EDT
Terminated Phase 2 Interventional

Chronic Sleep Deprivation as a Risk Factor for Metabolic Syndrome and Obesity

NCT00261898
View directory record Official record
Conditions
Obesity, Chronic Sleep Deprivation
Interventions
Increase sleep
Procedure
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 50 Years
Enrollment
239 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2013
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 3, 2015 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sensation Awareness Focused Training for Spouses

NCT03129204
View directory record Official record
Conditions
Post Intensive Care Syndrome, Anxiety, Depression, Posttraumatic Stress Disorder, Sleep Deprivation
Interventions
SAF-T
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2020 · Synced Jul 21, 2026, 6:45 AM EDT
Completed Phase 3 Interventional Results available

A Randomized Controlled Trial of Mandatory Naps for Physicians in Training

NCT00874510
View directory record Official record
Conditions
Fatigue
Interventions
Mandatory Naps
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2016 · Synced Jul 21, 2026, 6:45 AM EDT