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ClinicalTrials.gov public records Last synced Oct 19, 2026, 10:42 PM EDT

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Showing 217–240 of 2,614 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbance Clear all
Terminated Not applicable Interventional Results available

OSA Screen Negative With Spinal Duramorph

NCT03151226
View directory record Official record
Conditions
Respiratory Depression
Interventions
Capnography monitoring
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 7, 2018 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

ThermoSmart® Versus Conventional Humidification in Continuous Positive Airway Pressure (CPAP)

NCT00751335
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
CPAP with ThermoSmart, then CPAP without ThermoSmart, CPAP without ThermoSmart, then CPAP with ThermoSmart
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
18 Years and older
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 24, 2020 · Synced Oct 19, 2026, 10:42 PM EDT
Active, not recruiting Not applicable Interventional

Breathing Training for Improving Cardiovascular Health in Older Adults With Sleep Apnea

NCT04932447
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hypertension
Interventions
Inspiratory Muscle Strength Training
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
50 Years and older
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 19, 2026, 10:42 PM EDT
Not listed Not applicable Interventional

Comparing Insomnia Care As Usual to Digital Augmentation (CICADA)

NCT05490550
View directory record Official record
Conditions
Chronic Insomnia
Interventions
COAST-enhanced CBTI, Military Treatment Facility Insomnia Care As Usual
Behavioral
Lead sponsor
Noctem, LLC
Industry
Eligibility
18 Years and older
Enrollment
188 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lakewood, Washington
Source: ClinicalTrials.gov public record
Updated Mar 21, 2024 · Synced Oct 19, 2026, 10:42 PM EDT
Completed No phase listed Observational

Stimulation Therapy for Apnea: Reporting Thoughts

NCT04768543
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway stimulation (Inspire Medical Systems, Inc.)
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2022 · Synced Oct 19, 2026, 10:42 PM EDT
Enrolling by invitation Not applicable Interventional

Myofunctional Therapy for Obstructive Sleep Apnea

NCT07301125
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Myofunctional Therapy
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 19, 2026, 10:42 PM EDT
Active, not recruiting Not applicable Interventional

Dry Needling and Therapeutic Exercise on Sleep in Individuals With Chronic Neck Pain and Sleep Disturbance

NCT06275074
View directory record Official record
Conditions
Neck Pain, Sleep Disturbance
Interventions
Dry Needling, Therapeutic Exercise
Procedure · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Oct 19, 2026, 10:42 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Effect of Sleep Deprivation on Cognitive Function Among Cardiology Fellows

NCT05513339
View directory record Official record
Conditions
Wellness, Burnout, Sleep Deprivation, Executive Function
Interventions
WHOOP strap 4.0
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 99 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Oct 19, 2026, 10:42 PM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Study of Lunesta Versus Placebo for Sleep Problems Related to Smoking Cessation and Zyban

NCT00511134
View directory record Official record
Conditions
Insomnia, Nicotine Dependence
Interventions
Eszopiclone, Bupropion
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 19, 2026, 10:42 PM EDT
Not listed Not applicable Interventional

Evaluating Neuromodulation Technologies in Early Recovery

NCT01993277
View directory record Official record
Conditions
Depression, Anxiety, Insomnia
Interventions
Nexalin Brain Stimulator, Fischer Wallace Stimulator, David Delight Stimulator, Relaxation Therapy
Device · Behavioral
Lead sponsor
Behavioral Health of the Palm Beaches
Industry
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
North Palm Beach, Florida
Source: ClinicalTrials.gov public record
Updated Dec 17, 2014 · Synced Oct 19, 2026, 10:42 PM EDT
Completed No phase listed Observational

Oxidative Stress in Obstructive Sleep Apnea: Correlation of Biomarkers and Nasal CPAP Compliance

NCT01661699
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Not listed
Lead sponsor
Georgetown University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 28, 2014 · Synced Oct 19, 2026, 10:42 PM EDT
Completed No phase listed Observational

Hypertension and Sleep Disordered Breathing in Pediatrics

NCT00990899
View directory record Official record
Conditions
Hypertension, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
NYU Langone Health
Other
Eligibility
10 Years to 17 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Mineola, New York
Source: ClinicalTrials.gov public record
Updated Feb 6, 2019 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Apnea Hypopnea Index Severity Versus Head Position During Sleep

NCT04086407
View directory record Official record
Conditions
Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive, Snoring
Interventions
Dual-axis inclinometer attached to the subject's forehead with tape
Device
Lead sponsor
Sleep Systems
Industry
Eligibility
21 Years to 60 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 19, 2026, 10:42 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Study of Pain Processing in Subjects Suffering From Obstructive Sleep Apnea

NCT00672737
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Remifentanil, Cold pain threshold and tolerance, Heat pain threshold and tolerance, Polysomnography
Drug · Procedure · Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 55 Years · Male only
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers

NCT01516372
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
GEn 1200mg, Gen 6000 mg, GEn Placebo, Moxifloxacin Placebo, Moxifloxacin
Drug
Lead sponsor
XenoPort, Inc.
Industry
Eligibility
18 Years to 50 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Safety and Efficacy of VEC-162 on Circadian Rhythm in Healthy Adult Volunteers

NCT00490945
View directory record Official record
Conditions
Circadian Rhythm Sleep Disorders
Interventions
VEC-162
Drug
Lead sponsor
Vanda Pharmaceuticals
Industry
Eligibility
18 Years to 50 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
2
States / cities
Boston, Massachusetts • Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 26, 2014 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Phase 3 Interventional

A Study of the Safety of Gabapentin in a Potential Over-the-Counter Population With Occasional Sleeplessness

NCT00666575
View directory record Official record
Conditions
Transient Insomnia
Interventions
Gabapentin, Placebo
Drug
Lead sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Industry
Eligibility
12 Years and older
Enrollment
2,105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
23
States / cities
Mobile, Alabama • Phoenix, Arizona • Beverly Hills, California + 17 more
Source: ClinicalTrials.gov public record
Updated Feb 2, 2021 · Synced Oct 19, 2026, 10:42 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effects of PrTMS on Performance

NCT05353244
View directory record Official record
Conditions
Sleep Quality, Cognition Improvement
Interventions
PrTMS, Sham
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years to 42 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 17, 2024 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

High-resolution, Relational, Resonance-based, Electroencephalic Mirroring (HIRREM) to Relieve Insomnia

NCT01971567
View directory record Official record
Conditions
Insomnia
Interventions
HIRREM
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Not applicable Interventional

NightWare Randomized Trial 02

NCT04040387
View directory record Official record
Conditions
Stress Disorders, Post-Traumatic, Combat Disorders, Ptsd, Nightmare, Nightmares, REM-Sleep Type, Nightmare Disorder With Associated Non-Sleep Disorder
Interventions
NightWare Therapeutic System, Sham NightWare
Device
Lead sponsor
NightWare
Industry
Eligibility
22 Years and older
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
4
States / cities
Bethesda, Maryland • Minneapolis, Minnesota • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Oct 19, 2026, 10:42 PM EDT
Enrolling by invitation Not applicable Interventional

SHADES Mechanistic Trial

NCT06041581
View directory record Official record
Conditions
Insomnia, Insomnia Chronic, Insomnia, Primary, Sleep Disturbance, Sleep Disorder, Cardiovascular Diseases, Heart Diseases, Coronary Artery Disease, Stroke, Autonomic Dysfunction, Systemic Inflammatory Response, Metabolic Disease
Interventions
Sleep Healthy Using The Internet (SHUTi), Telephonic CBT-I, Face-to-Face CBT-I, Active Control: Sleep Education/Hygiene, Symptom Monitoring, and Usual Primary Care
Behavioral · Other
Lead sponsor
Indiana University
Other
Eligibility
40 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Not applicable Interventional

The POSAtive Study: Study for the Treatment of Positional Obstructive Sleep Apnea

NCT03061071
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
NightBalance Sleep Position Trainer (SPT), Automated Adjusting Positive Airway Pressure (APAP)
Device
Lead sponsor
NightBalance
Industry
Eligibility
20 Years to 80 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
11
States / cities
Birmingham, Alabama • Glendale, Arizona • Gainesville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 21, 2018 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Not applicable Interventional Results available

Discontinuation of Hypnotics in Older Veterans

NCT03511209
View directory record Official record
Conditions
Insomnia
Interventions
CBTI plus taper method A, CBTI plus taper method B
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 14, 2024 · Synced Oct 19, 2026, 10:42 PM EDT
Completed Phase 1 Interventional

Investigating the Use of taVNS to Treat Insomnia in Individuals With Breast Cancer (taVNS-insomnia-BC)

NCT06006299
View directory record Official record
Conditions
Breast Cancer, Insomnia
Interventions
transauricular Vagus Nerve Stimulation
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
2
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 19, 2026, 10:42 PM EDT