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ClinicalTrials.gov public records Last synced Oct 23, 2026, 6:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 769–792 of 2,614 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbance Clear all
Suspended Not applicable Interventional Accepts healthy volunteers

Light Exposure to Treat Sleep Disruption in Older People

NCT00427323
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders, Circadian Rhythm Sleep Disorders, Hypersomnia
Interventions
light exposure
Procedure
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
55 Years to 80 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2009 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Not applicable Interventional

Cognitive Behavioral Therapy for Trauma-Related Insomnia in Veterans

NCT01176123
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Southeast Louisiana Veterans Health Care System
Federal
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2020 · Synced Oct 23, 2026, 6:52 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women

NCT07678359
View directory record Official record
Conditions
Sleep Quality, Menopause
Interventions
Lotus Seed & Rice Germ Extract, Placebo
Dietary Supplement · Other
Lead sponsor
Nutraland USA, Inc.
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Not applicable Interventional

CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer Survivors

NCT02756390
View directory record Official record
Conditions
Insomnia
Interventions
CBTI-CS, Sleep Hygiene, CBTI-CS via Telehealth
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 11, 2018 · Synced Oct 23, 2026, 6:52 AM EDT
Not listed No phase listed Observational

Sleep Apnea in Look AHEAD (Action for Health in Diabetes)

NCT00194259
View directory record Official record
Conditions
Obstructive Sleep Apnea, Type 2 Diabetes
Interventions
Not listed
Lead sponsor
Temple University
Other
Eligibility
45 Years to 75 Years
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2014
U.S. locations
4
States / cities
New York, New York • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 7, 2014 · Synced Oct 23, 2026, 6:52 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Treatment Study Comparing Two Non-Drug, Self-Help Treatment of Chronic Insomnia.

NCT00310284
View directory record Official record
Conditions
Insomnia
Interventions
Computerized delivery of cognitive-behavioral treatment of insomnia, Self-help manual to improve insomnia symptoms
Behavioral
Lead sponsor
PICS, Inc.
Other
Eligibility
18 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2006
U.S. locations
1
States / cities
Reston, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 3, 2006 · Synced Oct 23, 2026, 6:52 AM EDT
Not listed Phase 4 Interventional

Effect of Atomoxetine on ADHD-Related Insomnia in Children and Adolescents

NCT00252278
View directory record Official record
Conditions
Attention-Deficit/Hyperactivity Disorder (ADHD), Insomnia
Interventions
atomoxetine
Drug
Lead sponsor
Rhode Island Hospital
Other
Eligibility
6 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 7, 2006 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 2 Interventional

CBT-I in Primary Brain Tumor Patients: Phase IIc Randomized Feasibility Pilot Trial

NCT06439420
View directory record Official record
Conditions
Primary Brain Tumor, Glioblastoma, Astrocytoma, Oligodendroglioma, Meningioma, Primary Central Nervous System (CNS) Lymphoma
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Sleep and Healthy Aging Research for Depression (SHARE-D) Study

NCT03256760
View directory record Official record
Conditions
Depression in Old Age
Interventions
Endotoxin, Placebo
Biological
Lead sponsor
Michael Irwin, MD
Other
Eligibility
60 Years to 80 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 5, 2024 · Synced Oct 23, 2026, 6:52 AM EDT
Active, not recruiting No phase listed Observational

Obstructive Sleep Apnea in Survivors of Hodgkin Lymphoma Treated With Thoracic Radiation

NCT03361020
View directory record Official record
Conditions
Obstructive Sleep Apnea, Hodgkin Lymphoma
Interventions
Not listed
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
434 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multi-center Clinical Trial of Limiting Resident Work Hours on ICU Patient Safety

NCT02134847
View directory record Official record
Conditions
Physician Fatigue
Interventions
SCS intervention schedule
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
21 Years and older
Enrollment
413 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
6
States / cities
Aurora, Colorado • Iowa City, Iowa • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Oct 23, 2026, 6:52 AM EDT
Terminated Phase 1 Interventional

A Study to Investigate Efficacy, Safety, Tolerability, and Pharmacokinetics of JZP441 Compared With Placebo in Participants With Narcolepsy Type 1

NCT06961266
View directory record Official record
Conditions
Narcolepsy
Interventions
JZP441, Matching Placebo
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years to 64 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
4
States / cities
Atlanta, Georgia • Cincinnati, Ohio • Columbia, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 1Phase 2 Interventional

Combination Pharmacological Interventions for Multiple Mechanisms of Obstructive Sleep Apnea

NCT03892772
View directory record Official record
Conditions
Sleep Apnea
Interventions
SAS0421a, SAS0421b, SAS0421c, placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 23, 2026, 6:52 AM EDT
Not listed Not applicable Interventional

The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea

NCT05428839
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Pharyngeal width measurement
Diagnostic Test
Lead sponsor
Inspire Medical Systems, Inc.
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
10
States / cities
Scottsdale, Arizona • Chicago, Illinois • Mason City, Iowa + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 23, 2026, 6:52 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

The Effect of Obstructive Sleep Apnea and Its Treatment on Decision Making

NCT03262519
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Computer based neurocognitive testing
Diagnostic Test
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 75 Years
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Pharmacokinetic and Safety of Ramelteon Between Adolescents With Insomnia and Healthy Adults

NCT00914862
View directory record Official record
Conditions
Insomnia
Interventions
Ramelteon
Drug
Lead sponsor
Takeda
Industry
Eligibility
6 Years to 50 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Overland Park, Kansas • Kalamazoo, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 4, 2012 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Not applicable Interventional

Use of an Educational Story to Prepare Children With Developmental Disabilities for Sleep Study

NCT02132273
View directory record Official record
Conditions
Developmental Disabilities, Sleep Disorders, Polysomnography, Preparation for Medical Procedure, Child
Interventions
Educational Story
Other
Lead sponsor
Jennifer Accardo
Other
Eligibility
4 Years to 17 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 27, 2016 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 1Phase 2 Interventional Results available

Botulinum Toxin to Treat Restless Legs Syndrome

NCT00479154
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
Botulinum Toxin A
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 26, 2012 · Synced Oct 23, 2026, 6:52 AM EDT
Recruiting Phase 3 Interventional

Sleep Quality and the Efficacy of a Multimodal Sleep Pathway in Hospitalized Orthopedic Trauma Patients

NCT07336277
View directory record Official record
Conditions
Orthopedic Trauma, Sleep Quality
Interventions
Standard Postoperative Care, Zolpidem, Melatonin, Sleep Hygiene Education, Actigraph GT3X-BT Actigraph
Other · Drug · Dietary Supplement + 2 more
Lead sponsor
Emory University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 30, 2026 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Safety and Tolerability of Gefapixant (MK-7264) in Participants With Obstructive Sleep Apnea (MK-7264-039)

NCT03882801
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA)
Interventions
Gefapixant, Placebo
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
4
States / cities
Hallandale, Florida • Hollywood, Florida • Atlanta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Oct 23, 2026, 6:52 AM EDT
Withdrawn Not applicable Interventional

Optimizing Cardiac Rehabilitation by Integrating Sleep Therapeutics

NCT04506112
View directory record Official record
Conditions
Sleep Wake Disorders, Sleep Disturbance, Sleep-Related Impairment
Interventions
Transdiagnostic Sleep and Circadian Intervention (TranS-C), adapted for cardiac rehabilitation
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 10, 2023 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Phase 3 Interventional

Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome

NCT00197080
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
Ropinirole Extended Release (XR)
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 79 Years
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
60
States / cities
Alabaster, Alabama • Jasper, Alabama • Mesa, Arizona + 55 more
Source: ClinicalTrials.gov public record
Updated Sep 23, 2016 · Synced Oct 23, 2026, 6:52 AM EDT
Completed No phase listed Observational

To Study the Prevalence of Insomnia in Geriatric COPD Patients Who Are Enrolled in a Pulmonary Rehabilitation Program.

NCT00346554
View directory record Official record
Conditions
COPD, Sleep Disorders
Interventions
Not listed
Lead sponsor
Hackensack Meridian Health
Other
Eligibility
60 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Hackensack, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 4, 2014 · Synced Oct 23, 2026, 6:52 AM EDT
Completed Not applicable Interventional Results available

Stroke and CPAP Outcome Study 3

NCT06029959
View directory record Official record
Conditions
Ischemic Stroke, Intra Cerebral Hemorrhage, Obstructive Sleep Apnea, Adherence, Treatment, Motivation
Interventions
Continuous positive airway pressure (CPAP), CPAP technical support intervention, Motivational Enhancement Therapy (MET), Mobile Health intervention
Device · Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 23, 2026, 6:52 AM EDT