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ClinicalTrials.gov public records Last synced Oct 27, 2026, 4:34 AM EDT

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Showing 1321–1344 of 2,614 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbance Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Validating the Use of a Subjectively Reported Sleep Vital Sign

NCT03018912
View directory record Official record
Conditions
Obstructive Sleep Apnea (OSA), Insomnia, Restless Leg Syndrome (RLS), Hypersomnia Type; Sleep Disorder, Shift Work Sleep Disorders
Interventions
Sleep VS
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
1,260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Fontana, California
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 27, 2026, 4:34 AM EDT
Active, not recruiting Not applicable Interventional

Safety and Effectiveness of the Genio® bilAteral Stimulation for Treatment of Complete Concentric CollapsE and OSA.

NCT05592002
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Genio System
Device
Lead sponsor
Nyxoah S.A.
Industry
Eligibility
22 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
16
States / cities
Colorado Springs, Colorado • Boca Raton, Florida • Miami, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Sep 5, 2025 · Synced Oct 27, 2026, 4:34 AM EDT
Withdrawn Phase 1Phase 2 Interventional

Cardiac Hemodynamics in Overlap Syndrome (COPD With Obstructive Sleep Apnea)

NCT01261377
View directory record Official record
Conditions
Chronic Obstructive Airway Disease
Interventions
Bi-level positive airway pressure (BPAP), Oxygen, CPAP
Device · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 12, 2017 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Phase 2 Interventional Results available

AD109 Dose Finding in Mild to Moderate OSA

NCT04631107
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
AD109 dose1- A, AD109 dose2- B, Placebo- C
Drug
Lead sponsor
Apnimed
Industry
Eligibility
25 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
San Diego, California • Atlanta, Georgia • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes

NCT06347744
View directory record Official record
Conditions
Sleep, Sleep Disturbance, Sleep Disorder
Interventions
Radicle Rest Placebo Control Form 1, Radicle Rest Active Study Product 1.1 Usage, Radicle Rest Placebo Control Form 2, Radicle Rest Active Study Product 2.1 Usage, Radicle Rest Placebo Control 4.1.0, Radicle Rest Active Study Product 4.1.1 Usage
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years
Enrollment
1,646 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Oct 6, 2025 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional Results available

Evaluation of an Algorithm to Detect Sleep and Wake in Continuous Positive Airway Pressure (CPAP)

NCT01031914
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Paced Breathing
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 70 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 14, 2013 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation

NCT06560411
View directory record Official record
Conditions
Obstructive Sleep Apnea, Obesity Hypoventilation Syndrome (OHS), Chronic Obstructive Pulmonary Disease (COPD), Neuromuscular Diseases (NMD)
Interventions
Non-Invasive Ventilation
Device
Lead sponsor
Breas Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
4
States / cities
Scottsdale, Arizona • San Diego, California • Colorado Springs, Colorado + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2026 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Intervention for Sleep and Pain in Youth

NCT03137147
View directory record Official record
Conditions
Headache Disorders, Migraine Disorders, Insomnia
Interventions
Intervention for Sleep and Pain in Youth
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Oct 27, 2026, 4:34 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Sleep Trial to Prevent Alzheimer's Disease

NCT04629547
View directory record Official record
Conditions
Sleep, Alzheimer Disease
Interventions
Suvorexant 20 mg, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
65 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 27, 2026, 4:34 AM EDT
Terminated Not applicable Interventional

Determination of Upper Airway Collapsibility During Routine CPAP Titration

NCT02566278
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Upper airway collapsibility (Pcrit)
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 79 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2019 · Synced Oct 27, 2026, 4:34 AM EDT
Not yet recruiting Phase 2 Interventional

THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia

NCT07565974
View directory record Official record
Conditions
Insomnia, Malignant Solid Neoplasm
Interventions
Biospecimen Collection, Placebo Administration, Single Agent Therapy
Procedure · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
25 Years and older
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Phase 2 Interventional Results available

Evaluation of an Oral Cannabidiol (CBD)-Terpene Formulation on Sleep Physiology in Participants With Insomnia

NCT05233761
View directory record Official record
Conditions
Insomnia
Interventions
Defined CBD, Placebo
Drug
Lead sponsor
Defined Research
Industry
Eligibility
25 Years to 70 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 11, 2025 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional

Biobehavioral Intervention to Enhance Hematopoietic Stem Cell Transplant Recovery

NCT02955043
View directory record Official record
Conditions
Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Plasma Cell Myeloma, Lymphoid Leukemia, Myeloid Leukemia, Myelodysplastic Syndromes, Multiple Myeloma
Interventions
Behavioral techniques
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 74 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 15, 2019 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury

NCT02374918
View directory record Official record
Conditions
Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
Interventions
mTBI wavelength-1 bright light, mTBI wavelength-2 bright light, HC wavelength-1 bright light, HC wavelength-2 bright light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 27, 2026, 4:34 AM EDT
Recruiting Not applicable Interventional

Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients

NCT06468618
View directory record Official record
Conditions
Stem Cell Transplant Complications, Sleep Disturbance
Interventions
DREAMS Program Video and Care Kit
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
9 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 27, 2026, 4:34 AM EDT
Terminated Phase 4 Interventional Results available

Inhaled Fluticasone Effects on Upper Airway Patency in Obstructive Lung Disease

NCT01554488
View directory record Official record
Conditions
Asthma, Chronic Obstructive Pulmonary Disease, Obstructive Sleep Apnea
Interventions
Inhaled Fluticasone Propionate
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Feb 5, 2020 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Chorus Sleep Trial

NCT05434143
View directory record Official record
Conditions
Sleep Disturbance
Interventions
Chorus Sleep
Behavioral
Lead sponsor
Chorus Wellness Inc.
Industry
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Nov 1, 2022 · Synced Oct 27, 2026, 4:34 AM EDT
Not listed No phase listed Observational

Reiterative Development and Evaluation Study of OSA Therapy System

NCT01634074
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
ApniCure, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
7
States / cities
Burlingame, California • Redwood City, California • Atlanta, Georgia + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 25, 2013 · Synced Oct 27, 2026, 4:34 AM EDT
Terminated Not applicable Interventional

Rainbow Acoustic Monitoring (RAM) Clinical Engineering Data Collection

NCT03120897
View directory record Official record
Conditions
Sleep Apnea
Interventions
RAM sensor
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
Up to 70 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 18, 2021 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Phase 2 Interventional Results available

Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases

NCT00001723
View directory record Official record
Conditions
Diabetes Mellitus, Hypertension, Metabolic Disease, Obesity, Sleep Apnea Syndrome
Interventions
Orlistat, Placebo
Drug
Lead sponsor
Jack Yanovski
NIH
Eligibility
12 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 18, 2012 · Synced Oct 27, 2026, 4:34 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Assessment of Human Sleep and Its Functions

NCT07211646
View directory record Official record
Conditions
Insomnia
Interventions
sham tES, Fixed tES, Personalized tES
Other
Lead sponsor
StimScience Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 27, 2026, 4:34 AM EDT
Completed No phase listed Observational

L-5-HTP-Related EMS

NCT00001918
View directory record Official record
Conditions
Eosinophilia-Myalgia Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Exercise on Sleep and Brain Health

NCT04210882
View directory record Official record
Conditions
Aging, Sleep Disorder
Interventions
Moderate-Intensity Exercise
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
50 Years to 75 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 1, 2022 · Synced Oct 27, 2026, 4:34 AM EDT
Completed Phase 4 Interventional Results available

Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome

NCT00822679
View directory record Official record
Conditions
Acute Coronary Syndrome, Sleep Disorder
Interventions
Eszopiclone, Placebo
Drug · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 20, 2016 · Synced Oct 27, 2026, 4:34 AM EDT