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ClinicalTrials.gov public records Last synced Oct 27, 2026, 4:29 PM EDT

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Showing 1417–1440 of 2,615 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbance Clear all
Withdrawn Not applicable Interventional

A Single-center Pilot Study Evaluating the Immediate Effects of Low-dose Acetazolamide on Respiratory Control in Subjects With Treatment Emergent Sleep Disordered Breathing

NCT02670096
View directory record Official record
Conditions
Sleep Apnea
Interventions
Acetazolamide
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Oct 27, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Effect of Sleep Deprivation and Recovery Sleep on Emotional Memory and Affective Reactivity

NCT03767426
View directory record Official record
Conditions
Sleep Deprivation, Sleep
Interventions
Sleep Deprivation, Daytime nap
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 27, 2026, 4:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

TipTraQ Home Sleep Test Validation Study, Duke

NCT06351878
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
PranaQ Pte. Ltd.
Industry
Eligibility
20 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 22, 2024 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners

NCT06250725
View directory record Official record
Conditions
Sleep Disturbance, Dementia
Interventions
Cognitive Behavioral Therapy for Insomnia
Behavioral
Lead sponsor
Emory University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 27, 2026, 4:29 PM EDT
Withdrawn Not applicable Interventional

Airway Ultrasound Prediction and Correlation

NCT03313947
View directory record Official record
Conditions
Obstructive Sleep Apnea, Difficult Airway
Interventions
Ultrasound, Questionnaire
Procedure · Other
Lead sponsor
Vidya Raman
Other
Eligibility
3 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 27, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Non-invasive Nerve Stimulation for PTSD and Sleep

NCT03170440
View directory record Official record
Conditions
Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions
Transcutaneous nerve stimulation location 1
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 55 Years
Enrollment
221 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2025
U.S. locations
3
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2025 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Study of Paxil Use in Menopausal Women

NCT00225914
View directory record Official record
Conditions
Menopause
Interventions
Paroxetine, placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
40 Years and older · Female only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 24, 2010 · Synced Oct 27, 2026, 4:29 PM EDT
Active, not recruiting No phase listed Observational

Database Study to Provide Information on Pregnancy and Infant Outcomes Among Women Exposed to QUVIVIQ (Daridorexant)

NCT06393504
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Daridorexant, Non-orexin receptor antagonist insomnia medication, No insomnia medication
Drug · Other
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
15 Years to 50 Years · Female only
Enrollment
2,095 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 27, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional

RISE: A Remote Study of Insomnia Treatment in Crohn's Disease

NCT05956158
View directory record Official record
Conditions
Insomnia, Crohn Disease
Interventions
Behavioral Treatment, Sleep Education Treatment
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep for Inpatients: Empowering Staff to Act

NCT02025959
View directory record Official record
Conditions
Sleep Disorders, Sleep
Interventions
Educating hospital staff on good sleep hygiene for patients and screening for sleep disorders
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 10, 2024 · Synced Oct 27, 2026, 4:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Circadian Regulation of Sleep in Habitual Short Sleepers and Long Sleepers

NCT00001546
View directory record Official record
Conditions
Sleep Disorders
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Auto Bilevel Adherence Following a Poor Initial Encounter With Continuous Positive Airway Pressure (CPAP)

NCT02522442
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
CPAP, Auto BiLevel
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
3
States / cities
Boston, Massachusetts • Rochester, Minnesota • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 26, 2019 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Phase 2 Interventional

RECOVER-SLEEP: Platform Protocol

NCT06404086
View directory record Official record
Conditions
Long COVID, Long COVID-19, Hypersomnia, Sleep Disturbance
Interventions
Modafinil, Modafinil Placebo, Solriamfetol, Solriamfetol Placebo, Melatonin, Melantonin Placebo, Tailored lighting (TL) Active, Tailored lighting (TL) Placebo
Drug · Device
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
830 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
47
States / cities
Phoenix, Arizona • Tucson, Arizona • Palo Alto, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Brain Training to Enhance Frontal Lobe Reasoning

NCT01552473
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Brain Training Program 1, Brain Training Program 2
Behavioral
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
19 Years to 65 Years
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 27, 2026, 4:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

NCT05309473
View directory record Official record
Conditions
Sleep Deprivation, Sleep Restriction, Acoustic Stimulation, Performance, Alertness
Interventions
Philips SmartSleep Acoustic Stimulation Device, Sham (no Acoustic Stimulation)
Device
Lead sponsor
Walter Reed Army Institute of Research (WRAIR)
Federal
Eligibility
18 Years to 39 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Silver Spring, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 23, 2024 · Synced Oct 27, 2026, 4:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Magnetoencephalographic (MEG) Localization of Ramelteon's Effects on Brain Function and Cortical Arousal in Insomnia

NCT00688025
View directory record Official record
Conditions
Insomnia
Interventions
Not listed
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 55 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 31, 2010 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional

CBT Insomnia Teens: Augmenting SSRIs to Improve Youth Depression

NCT02290496
View directory record Official record
Conditions
Insomnia, Depression
Interventions
CBT for Insomnia (CBT-I), Sleep Hygiene (SH)
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
12 Years to 19 Years
Enrollment
165 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Dec 17, 2018 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Comparing Auto-adjustable Positive Airway Pressure to Continuous Positive Airway Pressure in Children With Sleep Apnea

NCT01846988
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
crossover treatment (REMstar Auto A-Flex)
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 20 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 27, 2026, 4:29 PM EDT
Withdrawn Not applicable Interventional

Using Continuous Positive Airway Pressure to Reduce the Incidence of Acute Kidney Injury in Hospitalized Patients With Chronic Kidney Disease

NCT01859260
View directory record Official record
Conditions
Chronic Kidney Disease, Obstructive Sleep Apnea
Interventions
CPAP/autopap
Device
Lead sponsor
University of South Florida
Other
Eligibility
19 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Phase 2 Interventional Results available

Tiagabine to Enhance Slow Wave Sleep in Patients With Sleep Apnea

NCT02387710
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Tiagabine, Placebo
Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 79 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 15, 2017 · Synced Oct 27, 2026, 4:29 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Facilitating Adjustment to Simulated Jet Lag

NCT05382923
View directory record Official record
Conditions
Circadian Rhythm Sleep Disorder, Jet Lag Type
Interventions
Bright Light, Bright Light + Exercise + Melatonin, Control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 27, 2026, 4:29 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Assessment of Human Sleep and Its Functions

NCT07211646
View directory record Official record
Conditions
Insomnia
Interventions
sham tES, Fixed tES, Personalized tES
Other
Lead sponsor
StimScience Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional Results available

Glutathione and Health With Post-Polio Syndrome

NCT01402570
View directory record Official record
Conditions
Post-polio Syndrome, Physical Activity, Depression, Pain, Sleep Disorders
Interventions
Glutathione
Dietary Supplement
Lead sponsor
University of Michigan
Other
Eligibility
50 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 17, 2017 · Synced Oct 27, 2026, 4:29 PM EDT
Completed Not applicable Interventional

Hepatic Drug Biotransformation in Children With Obstructive Sleep Apnea

NCT00310323
View directory record Official record
Conditions
Sleep Apnea
Interventions
Dextromethorphan, Caffeine
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years to 16 Years
Enrollment
69 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
2
States / cities
Louisville, Kentucky • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2009 · Synced Oct 27, 2026, 4:29 PM EDT