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ClinicalTrials.gov public records Last synced Oct 28, 2026, 9:51 AM EDT

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Showing 1489–1512 of 2,616 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbance Clear all
Recruiting No phase listed Observational

Baker Gordon Syndrome Natural History Study

NCT06399952
View directory record Official record
Conditions
Rare Diseases, Autism or Autistic Traits, Development Delay, SYT-SSX Fusion Protein Expression, Sleep Disorder, Epilepsy, Generalized, Motor Delay
Interventions
Brain Magnetic Resonance Imaging (MRI), Whole Genome Sequencing, Induced Pluripotential Stem Cells
Diagnostic Test · Genetic · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
0 Years to 99 Years
Enrollment
50 participants
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Phase 2 Interventional Results available

BEN-2001 in Parkinson Disease Patients With Excessive Daytime Sleepiness

NCT03194217
View directory record Official record
Conditions
Excessive Daytime Sleepiness, Parkinson Disease
Interventions
BEN-2001, Placebo
Drug
Lead sponsor
BenevolentAI Bio
Industry
Eligibility
50 Years to 80 Years
Enrollment
244 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Oct 28, 2026, 9:51 AM EDT
Withdrawn Not applicable Interventional

Airway Ultrasound Prediction and Correlation

NCT03313947
View directory record Official record
Conditions
Obstructive Sleep Apnea, Difficult Airway
Interventions
Ultrasound, Questionnaire
Procedure · Other
Lead sponsor
Vidya Raman
Other
Eligibility
3 Years to 12 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 7, 2020 · Synced Oct 28, 2026, 9:51 AM EDT
Not listed No phase listed Observational

Capnography in the Post-Anesthesia Care Unit (PACU)

NCT03076047
View directory record Official record
Conditions
Obstructive Sleep Apnea, Bariatric Surgery Candidate, Respiratory Insufficiency
Interventions
end-tidal CO2 (ETCO2) monitoring
Device
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 30, 2022 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Not applicable Interventional

Evaluation of Gastroesophageal Reflux in Patients on Continuous Positive Airway Pressure Ventilation for Obstructive Sleep Apnea

NCT00194376
View directory record Official record
Conditions
Gastroesophageal Reflux, Sleep Apnea
Interventions
Continuous positive airway pressure ventilation
Procedure
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 19, 2018 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Not applicable Interventional

Sleep and Pain in Sickle Cell Disease

NCT03150433
View directory record Official record
Conditions
Sickle Cell Disease, Sleep Disturbance, Pain
Interventions
Behavioral symptom management, Sickle cell disease management
Behavioral · Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 24, 2025 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Phase 3 Interventional Results available

Study to Assess the Long Term Safety and Tolerability of ACT-541468 (Daridorexant) in Adult and Elderly Subjects Suffering From Difficulties to Sleep

NCT03679884
View directory record Official record
Conditions
Insomnia Disorder
Interventions
Daridorexant 10 mg, Daridorexant 25 mg, Daridorexant 50 mg, Placebo
Drug
Lead sponsor
Idorsia Pharmaceuticals Ltd.
Industry
Eligibility
18 Years and older
Enrollment
804 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
53
States / cities
Birmingham, Alabama • Glendale, Arizona • Tucson, Arizona + 47 more
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 28, 2026, 9:51 AM EDT
Completed No phase listed Observational Results available

Obstructive Sleep Apnea Endotypes and Impact on Phenotypes of People Living With HIV

NCT03575143
View directory record Official record
Conditions
Human Immunodeficiency Virus, Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 65 Years
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 21, 2023 · Synced Oct 28, 2026, 9:51 AM EDT
Not listed Not applicable Interventional

Monitored Breathing Awareness Therapy for Insomnia Disorder in Older Adults-2

NCT03187340
View directory record Official record
Conditions
Insomnia
Interventions
Sleep education and relaxation 1, Sleep education and relaxation 2
Behavioral
Lead sponsor
Nalaka Gooneratne
Other
Eligibility
55 Years and older
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Oct 28, 2026, 9:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

UCLA REST Study (REsearch on Sleep Techniques)

NCT05576090
View directory record Official record
Conditions
Sleep Disturbance, Inflammation, Psychosocial Functioning
Interventions
Mindfulness Meditation, Sleep Education
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 22 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Sep 23, 2026 · Synced Oct 28, 2026, 9:51 AM EDT
Completed No phase listed Observational

Evaluation of the Noga System: Detecting of Respiratory Related Sleep Disorders in Cardiac Patients

NCT00800397
View directory record Official record
Conditions
Sleep Apnea
Interventions
Not listed
Lead sponsor
WideMed LTD.
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Morristown, New Jersey
Source: ClinicalTrials.gov public record
Updated Aug 12, 2009 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Not applicable Interventional Results available

Effects of CPAP on Diet, Physical Activity, and Cardiovascular Risk

NCT01944020
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
CPAP
Device
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 3, 2022 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Not applicable Interventional

Targeted Hypoglossal Neurostimulation Study #3

NCT02263859
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
aura6000 System
Device
Lead sponsor
ImThera Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
138 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
14
States / cities
Chula Vista, California • Los Angeles, California • San Diego, California + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Not applicable Interventional Results available

Adherence to Electrical Glossal In Situ Stimulation for Sleep Apnea (AEGIS Study)

NCT04974515
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
eXciteOSA
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Oct 16, 2023 · Synced Oct 28, 2026, 9:51 AM EDT
Completed No phase listed Observational

Prevalence of Sleep-Disordered Breathing in Children

NCT00022789
View directory record Official record
Conditions
Lung Diseases, Sleep Apnea Syndromes
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
5 Years to 12 Years
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 13, 2014 · Synced Oct 28, 2026, 9:51 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Effect of ZenRest™ Lotus Seed & Rice Germ Extract Blend on Sleep Quality in Menopausal Women

NCT07678359
View directory record Official record
Conditions
Sleep Quality, Menopause
Interventions
Lotus Seed & Rice Germ Extract, Placebo
Dietary Supplement · Other
Lead sponsor
Nutraland USA, Inc.
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 28, 2026, 9:51 AM EDT
Recruiting Phase 4 Interventional

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

NCT07136415
View directory record Official record
Conditions
Menopausal Women, Insomnia
Interventions
Cognitive behavioral therapy for insomnia (CBT-i), Trazodone, Daridorexant
Behavioral · Drug
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
40 Years to 62 Years · Female only
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
5
States / cities
Boston, Massachusetts • Novi, Michigan • Winston-Salem, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 28, 2026, 9:51 AM EDT
Completed No phase listed Observational

Disentangling the Role of Depression in Hypersomnia

NCT05850676
View directory record Official record
Conditions
Hypersomnia
Interventions
Sleep study
Diagnostic Test
Lead sponsor
University of Pennsylvania
Other
Eligibility
21 Years to 55 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 28, 2026, 9:51 AM EDT
Not listed Phase 4 Interventional

Pitolisant in Refractory Restless Legs Syndrome

NCT05581576
View directory record Official record
Conditions
Restless Legs Syndrome
Interventions
Pitolisant
Drug
Lead sponsor
William Ondo, MD
Other
Eligibility
21 Years to 80 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 14, 2022 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate Safety, and Efficacy of SUVN-G3031 (Samelisant) in Patients With Narcolepsy With and Without Cataplexy

NCT04072380
View directory record Official record
Conditions
Narcolepsy
Interventions
SUVN-G3031, Placebo
Drug
Lead sponsor
Suven Life Sciences Limited
Industry
Eligibility
18 Years to 65 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
39
States / cities
Birmingham, Alabama • Los Angeles, California • San Diego, California + 30 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 28, 2026, 9:51 AM EDT
Recruiting Not applicable Interventional

Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients

NCT06468618
View directory record Official record
Conditions
Stem Cell Transplant Complications, Sleep Disturbance
Interventions
DREAMS Program Video and Care Kit
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
9 Years to 17 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 28, 2026, 9:51 AM EDT
Completed Not applicable Interventional Results available

Evaluation of the F&P Caramel Nasal Mask, US, 2023

NCT06060717
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
F&P Caramel
Device
Lead sponsor
Fisher and Paykel Healthcare
Industry
Eligibility
22 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 28, 2026, 9:51 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measuring Sleep Disturbance Among Cancer Patients

NCT00505544
View directory record Official record
Conditions
Advanced Cancer
Interventions
Questionnaire, Actigraph
Behavioral · Device
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
459 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2022
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 13, 2022 · Synced Oct 28, 2026, 9:51 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

NiteCAPP_HELPS_WD: Improving Sleep and Reducing Opioid Use in Chronic Pain Patients

NCT05226026
View directory record Official record
Conditions
Chronic Pain, Chronic Insomnia, Opioid Use
Interventions
NiteCAPP HELPS, Tapered Withdrawal
Behavioral · Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Aug 5, 2024 · Synced Oct 28, 2026, 9:51 AM EDT