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ClinicalTrials.gov public records Last synced Oct 1, 2026, 11:19 PM EDT

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Showing 49–72 of 131 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep Disturbances in Children Clear all
Completed No phase listed Observational Accepts healthy volunteers

Environmental Assessment of Sleep in Youth

NCT03224455
View directory record Official record
Conditions
Sleep Disorders in Children, Environmental Exposure
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
6 Years to 12 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Oct 1, 2026, 11:19 PM EDT
Not listed Not applicable Interventional

Outcomes of Post-operative Diet in Children Following Tonsillectomy and Adenoidectomy

NCT03437954
View directory record Official record
Conditions
Chronic Tonsillitis, Sleep Disordered Breathing
Interventions
Diet modification
Other
Lead sponsor
Georgetown University
Other
Eligibility
3 Years to 12 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Phase 2 Interventional Results available

Medications for Obstructive Sleep Apnea In Children With Down Syndrome

NCT04115878
View directory record Official record
Conditions
Obstructive Sleep Apnea, Down Syndrome
Interventions
Atomoxetine and oxybutynin (ato-oxy)
Drug
Lead sponsor
University of Arizona
Other
Eligibility
6 Years to 17 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 19, 2025 · Synced Oct 1, 2026, 11:19 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Treatment to Improve Sleep in Caregivers With Insomnia and a Child With Autism

NCT05373537
View directory record Official record
Conditions
Autism Spectrum Disorder, Insomnia Chronic, Caregiver Burden
Interventions
Cognitive behavioral therapy for Insomnia
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
3 Years to 100 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 1, 2026, 11:19 PM EDT
Completed No phase listed Observational

Urinary Leukotriene E4 Levels in Children With Obstructive Sleep Apnea

NCT02205346
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
2 Years to 16 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2018 · Synced Oct 1, 2026, 11:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Identification of Sleep-Disordered Breathing in Children

NCT00233194
View directory record Official record
Conditions
Sleep, Sleep Apnea Syndromes, Sleep Disordered Breathing
Interventions
Observational follow-up study of adenotonsillectomy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 12 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Phase 1 Interventional

Single Dose Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Evaluation of Eplivanserin in Children With Insomnia

NCT00913614
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
Eplivanserin (SR46349)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
6 Years to 17 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 30, 2010 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional

HSAT for OSA Management in Children

NCT05516524
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
Interventions
Home sleep apnea test, PSG
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 12 Years
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2025 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Omega-3 Fatty Acids on Sleep and Behavior (Pilot Study)

NCT03694314
View directory record Official record
Conditions
Disturbances in Initiating and Maintaining Sleep, Behavior Problem
Interventions
Omega-3 fatty acids, Placebo
Dietary Supplement
Lead sponsor
University of Pennsylvania
Other
Eligibility
5 Years to 9 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 8, 2019 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Targeting Sleep in Kids With Autism Spectrum Disorder

NCT02755051
View directory record Official record
Conditions
Autism Spectrum Disorder, Chronic Insomnia
Interventions
Cognitive Behavioral Therapy
Behavioral
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
6 Years to 12 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 20, 2018 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Phase 3 Interventional Results available

Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated Insomnia

NCT00857220
View directory record Official record
Conditions
Insomnia, Attention Deficit Hyperactivity Disorder
Interventions
eszopiclone
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
89
States / cities
Tucson, Arizona • Little Rock, Arkansas • Carson, California + 70 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 1, 2026, 11:19 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Research Study for Children About Heart Changes and Obstructive Sleep Apnea (OSA)

NCT01837459
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 13 Years
Enrollment
231 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2015
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 14, 2016 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional Results available

Continuous Positive Airway Pressure (CPAP) After Adenotonsillectomy in Children

NCT01554527
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Child Behavior Disorders, Attention Deficit Disorder With Hyperactivity, Disorders of Excessive Somnolence
Interventions
CPAP treatment, No CPAP treatment
Procedure · Other
Lead sponsor
University of Michigan
Other
Eligibility
5 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Oct 1, 2026, 11:19 PM EDT
Recruiting Not applicable Interventional

Home Apnea Testing in CHildren Trial

NCT05382754
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
Interventions
Home sleep apnea test, In-lab polysomnography
Diagnostic Test
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
5 Years to 12 Years
Enrollment
317 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Adenotonsillectomy on Quality of Life in Children With Mild Obstructive Sleep Apnea

NCT01539278
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
Adenotonsillectomy, Observation alone / no intervention
Procedure · Other
Lead sponsor
Eastern Virginia Medical School
Other
Eligibility
3 Years to 16 Years
Enrollment
113 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2015 · Synced Oct 1, 2026, 11:19 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Improving Maternal Sleep and Mental Health

NCT06544941
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Sleep Disturbance, Infant Behavior, Maternal Behavior, Inflammation, Military Family
Interventions
Smart Bassinet, HALO
Device
Lead sponsor
University of Colorado, Colorado Springs
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
342 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 1, 2026, 11:19 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Melatonin Studies of Totally Blind Children

NCT00795236
View directory record Official record
Conditions
Sleep Disorder, Blindness
Interventions
Melatonin
Drug
Lead sponsor
Oregon Health and Science University
Other
Eligibility
5 Years to 20 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 27, 2019 · Synced Oct 1, 2026, 11:19 PM EDT
Completed No phase listed Interventional Results available

Validation of ApneaLink Air Home Sleep Testing in the Diagnosis of Obstructive Sleep Apnea in Adolescent Children

NCT03748771
View directory record Official record
Conditions
Sleep Apnea, Obstructive
Interventions
ApneaLink Air
Device
Lead sponsor
ResMed
Industry
Eligibility
12 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2021 · Synced Oct 1, 2026, 11:19 PM EDT
Not listed Not applicable Interventional

Sleep Health in Preschoolers: a Randomized Controlled Trial

NCT02255721
View directory record Official record
Conditions
Sleep Initiation and Maintenance Disorders
Interventions
SHIP (Sleep Health in Preschoolers), SHIP Control Arm
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
30 Months to 71 Months
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Phase 3 Interventional Results available

Safety & Efficacy Study of Study Drug (Eszopiclone) in Children and Adolescents With Attention-deficit/Hyperactivity Disorder - Associated Insomnia

NCT00856973
View directory record Official record
Conditions
Insomnia, Attention Deficit Hyperactivity Disorder
Interventions
eszopiclone, Placebo
Drug
Lead sponsor
Sumitomo Pharma America, Inc.
Industry
Eligibility
6 Years to 17 Years
Enrollment
486 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
73
States / cities
Birmingham, Alabama • Dothan, Alabama • Chandler, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2013 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Study of PROVIGIL ® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy

NCT00107796
View directory record Official record
Conditions
Narcolepsy
Interventions
Modafinil
Drug
Lead sponsor
Cephalon
Industry
Eligibility
6 Years to 16 Years
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2005
U.S. locations
68
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 56 more
Source: ClinicalTrials.gov public record
Updated Aug 24, 2012 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mask Study: One-handed vs. Two Handed Technique in Children

NCT03215121
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
One handed mask airway, switch to two hands, Two handed mask airway + jaw thrust, Two handed mask airway, switch to one hand
Procedure
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Year to 8 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Jan 23, 2020 · Synced Oct 1, 2026, 11:19 PM EDT
Completed Not applicable Interventional

Novel Adaptive Cognitive Training in Autistic Adults With Co-occurring Insomnia

NCT06291298
View directory record Official record
Conditions
Autism Spectrum Disorder, Insomnia
Interventions
COGMUSE-AUT
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 1, 2026, 11:19 PM EDT
Recruiting Phase 4 Interventional

Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

NCT05042258
View directory record Official record
Conditions
Atopic Dermatitis, Sleep Disturbance
Interventions
Dupilumab
Drug
Lead sponsor
Northwestern University
Other
Eligibility
6 Years to 17 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 27, 2026 · Synced Oct 1, 2026, 11:19 PM EDT