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Showing 1–24 of 2,568 matching trials from the live ClinicalTrials.gov search.
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Completed Phase 2 Interventional

Continuous Positive Airway Pressure for the Treatment of Stroke

NCT00368628
View directory record Official record
Conditions
Acute Ischemic Stroke, Sleep Apnea
Interventions
continuous positive airway pressure
Procedure
Lead sponsor
Yale University
Other
Eligibility
50 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2008
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 2, 2009 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Efficacy of Ramelteon on Transient Insomnia in Healthy Adults

NCT00671398
View directory record Official record
Conditions
Transient Insomnia
Interventions
Ramelteon, Placebo
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years to 64 Years
Enrollment
289 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2003
U.S. locations
12
States / cities
Palm Springs, California • San Diego, California • Miami, Florida + 9 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2012 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional

Lighting Intervention to Improve Sleep

NCT05757414
View directory record Official record
Conditions
Parkinson Disease, Sleep Disturbance
Interventions
Tailored Lighting Intervention (LIT), Actigraph
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Jul 21, 2026, 11:05 AM EDT
Recruiting Phase 2 Interventional

Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)

NCT05565833
View directory record Official record
Conditions
Insomnia, Cognitive Dysfunction, Mild Cognitive Impairment, Sleep Initiation and Maintenance Disorders, Sleep Disorders, Intrinsic, Dyssomnias, Sleep Wake Disorders, Nervous System Diseases, Alzheimer Disease
Interventions
SHUTi OASIS, Patient Education
Behavioral · Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Jul 21, 2026, 11:05 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Impact of Exogenous Ketones on Sleep Apnea

NCT06687655
View directory record Official record
Conditions
Obstructive Sleep Apnea, Sleep
Interventions
Ketone-IQ, Placebo
Dietary Supplement
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional

Implementing and Sustaining a Transdiagnostic Sleep and Circadian Treatment

NCT03556878
View directory record Official record
Conditions
Sleep Disorders, Circadian Rhythm, Sleep Disorder, Acceptability, Feasibility, Adaptation, Implementation Research
Interventions
Fitted Transdiagnostic Sleep and Circadian intervention
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Using Mobile App on Perceived Stress During COVID-19 Pandemic

NCT04329533
View directory record Official record
Conditions
Perceived Stress, Anxiety, Sleep Disturbance
Interventions
"Calm" is a mindfulness meditation mobile app
Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 12, 2020 · Synced Jul 21, 2026, 11:05 AM EDT
Terminated Not applicable Interventional Results available

OSA Screen Negative With Spinal Duramorph

NCT03151226
View directory record Official record
Conditions
Respiratory Depression
Interventions
Capnography monitoring
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 6, 2018 · Synced Jul 21, 2026, 11:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lagged Relationships Between Sleep, Balance, and Cognition in Older Adults

NCT06584136
View directory record Official record
Conditions
Aging
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
65 Years to 95 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Jul 21, 2026, 11:05 AM EDT
Terminated Not applicable Interventional

Digital Behavioral Therapy for Sleep Problems

NCT04308499
View directory record Official record
Conditions
Insomnia
Interventions
Digital cognitive-behavioral therapy for insomnia (dCBTI), Sleep hygiene education (SHE)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older · Male only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2024 · Synced Jul 21, 2026, 11:05 AM EDT
Not listed Not applicable Interventional

Treatment of Insomnia and Depression in Elders (TIDE)

NCT01648049
View directory record Official record
Conditions
Depression, Insomnia
Interventions
Integrated Cognitive Behavioral Therapy (CBT), Treatment as usual
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
50 Years to 100 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Tuscaloosa, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 1, 2015 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

NCT06197243
View directory record Official record
Conditions
Anxiety, Insomnia, Benzodiazepine, Deprescription
Interventions
Acupuncture, Yoga, Deprescribing
Other
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
65 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Jul 21, 2026, 11:05 AM EDT
Not yet recruiting Phase 2 Interventional

Daridorexant for People With Insomnia and Alcohol Use Disorder Study

NCT07701928
View directory record Official record
Conditions
Alcohol Use Disorder, Insomnia
Interventions
Daridorexant, Placebo, Brief Counseling, MEMS and Medication Accounting, Contingency Management for Medication Adherence
Drug · Behavioral · Device
Lead sponsor
Sterling McPherson
Other
Eligibility
18 Years and older
Enrollment
205 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Jul 21, 2026, 11:05 AM EDT
Recruiting Phase 3 Interventional

AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

NCT07571109
View directory record Official record
Conditions
Obesity, Overweight, Obstructive Sleep Apnoea
Interventions
NNC0487-0111, Placebo (matched to NNC0487-0111)
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
20
States / cities
Gilbert, Arizona • Bradenton, Florida • Naples, Florida + 16 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Pilot Evaluation of the Insomnia Coach Mobile App

NCT03826849
View directory record Official record
Conditions
Insomnia, Trauma, Psychological
Interventions
Insomnia Coach
Behavioral
Lead sponsor
VA Palo Alto Health Care System
Federal
Eligibility
18 Years to 55 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Oct 14, 2021 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional Results available

Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia

NCT04846400
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Hypotonia, Child, Only
Interventions
ssNPA
Device
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 21 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Jul 21, 2026, 11:05 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Early Dental Risk Screening for Pediatric Sleep-Disordered Breathing

NCT07581938
View directory record Official record
Conditions
Early Risk Screening for Sleep Disordered Breathing in a Dental Setting, Sleep Disordered Breathing (SDB), Obstructive Sleep Apnea (OSA)
Interventions
SleepImage Ring
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
8 Years to 13 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Crossover Trial to Examine the Efficacy of a Powder to Improve Sleep Quality and Performance

NCT07183735
View directory record Official record
Conditions
Sleep, Sleep Disorder
Interventions
BEAM Dream Powder, Placebo Control
Dietary Supplement
Lead sponsor
Beam
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Sep 18, 2025 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional

Improving Sleep Quality in Flap Patients in the SICU

NCT03957317
View directory record Official record
Conditions
Sleep Deprivation
Interventions
Eye mask and ear plugs
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2019 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Phase 2 Interventional Results available

Propranolol for Sleep Apnea Therapy

NCT03049306
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Propranolol Oral Tablet, Placebo Oral Tablet
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
20 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 4, 2024 · Synced Jul 21, 2026, 11:05 AM EDT
Enrolling by invitation No phase listed Observational

Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

NCT03062748
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older
Enrollment
196 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Phase 1 Interventional

A Study to Evaluate the Efficacy, Safety, and Tolerability of E2086 Compared to Placebo and Active Comparator in Adult Participants With Narcolepsy Type 1

NCT06462404
View directory record Official record
Conditions
Narcolepsy Type 1 (NT1)
Interventions
E2086, E2086 Placebo, Active Comparator, Active Comparator Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
12
States / cities
Santa Ana, California • Miami, Florida • Macon, Georgia + 9 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2025 · Synced Jul 21, 2026, 11:05 AM EDT
Recruiting Not applicable Interventional

Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury

NCT05536076
View directory record Official record
Conditions
Sleep Apnea, SCI/D, Hypercapnia
Interventions
Hypercapnia treatment
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 1, 2026 · Synced Jul 21, 2026, 11:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Performance Evaluation of the Dreem 3 System for Sleep Assessment in Patients With Insomnia

NCT05438017
View directory record Official record
Conditions
Insomnia
Interventions
Dreem 3 System vs PSG
Device
Lead sponsor
Dreem
Industry
Eligibility
22 Years to 70 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Jul 21, 2026, 11:05 AM EDT