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ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:12 AM EDT

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Showing 1–24 of 142 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Sleep-Disordered Breathing Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea

NCT00607893
View directory record Official record
Conditions
Sleep Apnea Syndromes, Oxidative Stress, Cardiovascular Diseases
Interventions
Continuous Positive Airway Pressure (CPAP), Sham CPAP
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
20 Years to 75 Years
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 15, 2017 · Synced Oct 21, 2026, 9:12 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Software Enhancements to the Respironics BiPAP autoSV Device Compared to BiPAP S/T Device

NCT01241604
View directory record Official record
Conditions
Sleep Disordered Breathing
Interventions
BiPAP S/T, BiPAP Auto SV3
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 9, 2019 · Synced Oct 21, 2026, 9:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

OSA in Pregnant Women With Chronic HTN

NCT03230110
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pregnancy, Hypertension
Interventions
WP200U home sleep study device
Diagnostic Test
Lead sponsor
Duke University
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 24, 2019 · Synced Oct 21, 2026, 9:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Behavioral Effects of Obstructive Sleep Apnea in Children

NCT00060723
View directory record Official record
Conditions
Sleep-disordered Breathing, Sleep Apnea, Obstructive, ADHD
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
5 Years to 12 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2004
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional

Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing

NCT00004569
View directory record Official record
Conditions
Sleep-Disordered Breathing
Interventions
Non-invasive technique to diagnose and quantitate sleep-disordered breathing
Procedure
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 21, 2026, 9:12 AM EDT
Withdrawn No phase listed Observational

Egrifta Replacement and Sleep Disordered Breathing

NCT01788462
View directory record Official record
Conditions
Lipodystrophy
Interventions
Tesamorelin (Egrifta)
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2017 · Synced Oct 21, 2026, 9:12 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Novel Strategies for Reducing Heart Disease Risk Disparities

NCT00143923
View directory record Official record
Conditions
Cardiovascular Diseases
Interventions
Nutrition, Exercise, Stress Management Counseling, usual care
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
45 Years to 75 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 21, 2026, 9:12 AM EDT
Completed No phase listed Observational Results available

Validation of the ApneaLink Sleep Screener for Obstructive Sleep Apnea (OSA)

NCT00354614
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
ApneaLink Sleep Screener
Device
Lead sponsor
ResMed
Industry
Eligibility
18 Years and older
Enrollment
81 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 28, 2017 · Synced Oct 21, 2026, 9:12 AM EDT
Not listed Not applicable Interventional

Assessing the Performance of Wesper Lab for Sleep Apnea Diagnosis in Pediatric Populations

NCT06218186
View directory record Official record
Conditions
Sleep Apnea, Sleep Apnea Syndromes in Children, Sleep Apnea Syndromes
Interventions
Medical Device: Wesper Lab Home Sleep Test
Device
Lead sponsor
Wesper Inc
Industry
Eligibility
2 Years to 21 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Edmond, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jan 23, 2024 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea

NCT00307944
View directory record Official record
Conditions
Acid Reflux Disease, Obstructive Sleep Apnea
Interventions
Pantoprazole
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 12, 2007 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Phase 2 Interventional

Diagnosis and Treatment of Sleep-Disordered Breathing in the Homes of Patients With Transient Ischemic Attack

NCT00251290
View directory record Official record
Conditions
Transient Ischemic Attack, Sleep Apnea
Interventions
auto-titrating continuous positive airway pressure
Procedure
Lead sponsor
Yale University
Other
Eligibility
45 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
3
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 3, 2009 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Software Enhancements to the Respironics BiPAP Auto Servo Ventilation (AutoSV) Device

NCT00720213
View directory record Official record
Conditions
Sleep Disordered Breathing, Sleep Apnea, Central
Interventions
Respironics BiPAP autoSV2, Respironics BiPAP autoSV3
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 80 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
5
States / cities
Tucson, Arizona • Little Rock, Arkansas • Portage, Michigan + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 29, 2019 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional

SIESTA (Sleep of Inpatients: Empower Staff to Act) for Acute Stroke Rehabilitation

NCT04254484
View directory record Official record
Conditions
Sleep, Sleep Disordered Breathing, Stroke
Interventions
SIESTA Rehab Education, ApneaLink
Behavioral · Diagnostic Test
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Detection of Sleep Stages and Arousals Using Neural Network Classifiers

NCT07136272
View directory record Official record
Conditions
Sleep Disordered Breathing (SDB), Sleep Apnea
Interventions
SSAM, Polysomnography, EnsoSleep
Device · Diagnostic Test
Lead sponsor
Pathway Medtech, LLC.
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
3
States / cities
Burlingame, California • Irvine, California • La Jolla, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 21, 2026, 9:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Snoring in Pregnancy and Adverse Maternal and Fetal Outcomes

NCT01030003
View directory record Official record
Conditions
Sleep Apnea Syndromes
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older · Female only
Enrollment
1,685 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 7, 2012 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Comparison of SomnaPatch With Polysomnography in Sleep Disordered Breathing

NCT02034175
View directory record Official record
Conditions
Obstructive Sleep Apnea, Central Sleep Apnea, Mixed Sleep Apnea, Cheyne-Stokes Respiration
Interventions
SomnaPatch, Polysomnography
Device
Lead sponsor
Somnarus Inc
Industry
Eligibility
20 Years to 85 Years
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
3
States / cities
Little Rock, Arkansas • Burlingame, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Oct 3, 2019 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Determination of the Predictors of Nocturnal Desaturation in Postpartum Women

NCT02330055
View directory record Official record
Conditions
Sleep Disordered Breathing, Nocturnal Oxygen Desaturation, Upper Airway Edema
Interventions
Forty-five degrees elevated upper body position, non-elevated upper body position, Noninvasive wrist pulse oximeter (WristOx Model 3150), Stop-Bang questionnaire, Epworth Sleepiness Scale, P-SAP Score, self-reported pain
Procedure · Device · Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 6, 2018 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional Results available

Transcend Auto vs Commercially Available Device Clinical Evaluation for Treatment of Obstructive Sleep Apnea (OSA)

NCT01799265
View directory record Official record
Conditions
Obstructive Sleep Apnea
Interventions
Somnetics Transcend Auto, Respironics REMstar Auto with C-Flex
Device
Lead sponsor
Somnetics International, Inc.
Industry
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013
U.S. locations
3
States / cities
Coon Rapids, Minnesota • Plymouth, Minnesota • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 21, 2026, 9:12 AM EDT
Not listed No phase listed Observational

Association of Hypertensive Disorder of Pregnancy With Sleep-disordered Breathing.

NCT04126629
View directory record Official record
Conditions
Hypertensive Disorder of Pregnancy, Sleep-disordered Breathing
Interventions
Not listed
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 21, 2026, 9:12 AM EDT
Terminated Not applicable Interventional Results available

A Pilot Study to Assess the Effects of a Novel Application of Averaged Volume Assured Pressure Support Ventilation (AVAPS-AE) Therapy on Re-hospitalization in Patients With Sleep-Disordered Breathing With Co-morbid COPD

NCT02446769
View directory record Official record
Conditions
Breathing-Related Sleep Disorder
Interventions
AVAPS-AE Non-invasive ventilation therapy
Device
Lead sponsor
Philips Respironics
Industry
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 5, 2020 · Synced Oct 21, 2026, 9:12 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Identification of Sleep-Disordered Breathing in Children

NCT00233194
View directory record Official record
Conditions
Sleep, Sleep Apnea Syndromes, Sleep Disordered Breathing
Interventions
Observational follow-up study of adenotonsillectomy
Procedure
Lead sponsor
University of Michigan
Other
Eligibility
3 Years to 12 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 6, 2016 · Synced Oct 21, 2026, 9:12 AM EDT
Withdrawn Not applicable Interventional

Effect of Treating Sleep Disorder Breathing in Patients With Resistant Hypertension

NCT00973531
View directory record Official record
Conditions
Sleep Apnea, Hypertension
Interventions
Autotitrating Positive Airway Pressure (APAP), Traditional Split Titration Polysomnogram
Device
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 26, 2012 · Synced Oct 21, 2026, 9:12 AM EDT
Recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

Sleep Disordered Breathing With Opioid Use

NCT05589753
View directory record Official record
Conditions
Sleep Apnea, Opioid Use, Sleep Disordered Breathing
Interventions
Hyperoxia, Acetazolamide
Other · Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Oct 21, 2026, 9:12 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

User Preference/Validation Evaluation of the New Philips Respironics Positive Airway Pressure Application

NCT03748264
View directory record Official record
Conditions
Sleep Disordered Breathing
Interventions
Standard of Care, DreamMapper Application, DreamMapper Application with Therapist Assist
Other · Device
Lead sponsor
Philips Respironics
Industry
Eligibility
21 Years to 75 Years
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
5
States / cities
Little Rock, Arkansas • Atlanta, Georgia • Indianapolis, Indiana + 2 more
Source: ClinicalTrials.gov public record
Updated Mar 12, 2021 · Synced Oct 21, 2026, 9:12 AM EDT