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ClinicalTrials.gov public records Last synced Nov 13, 2026, 12:00 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 265–288 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Parkinson Disease, Multiple System Atrophy, REM Sleep Behavior Disorder, Pure Autonomic Failure, Dementia With Lewy Bodies
Interventions: Not listed
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years and older
Enrollment: 166 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2020
U.S. locations: 1
States / cities: New York, New York

Conditions: Obstructive Sleep Apnea
Interventions: Bright light therapy glasses; Device
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 50 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Obesity Hypoventilation Syndrome
Interventions: AVAPS-AE Mode of Therapy, Respironics OnmiLab BiPAP S mode, Respironics OmniLab Advanced CPAP mode; Device
Lead sponsor: Philips Respironics; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2013
U.S. locations: 2
States / cities: Tucson, Arizona • Chicago, Illinois

Conditions: Cognitive, Mood and Cognitive Performance, Sleep Deprivation, Executive Function (Cognition), Fatigue
Interventions: Alpha Brain proprietary cognitive dietary supplement, Alpha Brain 2.0 proprietary cognitive dietary supplement, Controlled Placebo; Dietary Supplement
Lead sponsor: Applied Science & Performance Institute; Industry
Eligibility: 20 Years to 59 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Tampa, Florida

Conditions: Mental Illness, Burnout Syndrome
Interventions: Not listed
Lead sponsor: Scripps Translational Science Institute; Other
Eligibility: 19 Years and older
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2017
U.S. locations: 1
States / cities: San Diego, California

Conditions: Sleep Apnea
Interventions: RAM sensor; Device
Lead sponsor: Masimo Corporation; Industry
Eligibility: Up to 70 Years
Enrollment: 78 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Stanford, California

Conditions: Insomnia, Posttraumatic Stress Disorder, Cardiovascular Risk Factor
Interventions: Cognitive Behavior Therapy for Insomnia, Weekly phone contacts; Behavioral
Lead sponsor: Duke University; Other
Eligibility: 40 Years to 59 Years
Enrollment: 140 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Transient Insomnia
Interventions: SM-1, D+Z, D+L, Placebo; Drug
Lead sponsor: Sequential Medicine Ltd; Industry
Eligibility: 18 Years and older
Enrollment: 85 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 2
States / cities: Atlanta, Georgia • New York, New York

Conditions: Obstructive Sleep Apnea
Interventions: Acetazolamide 500 MG QHS, Eszopiclone 3 mg QHS; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 21 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2028
U.S. locations: 2
States / cities: Santa Monica, California • Westwood, Los Angeles, California

Conditions: Restless Legs Syndrome, Iron Deficiency Anemia
Interventions: Ferumoxytol intravenous, Ferrous sulfate; Drug
Lead sponsor: Auerbach Hematology Oncology Associates P C; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Posttraumatic Stress Disorders, Chronic Insomnia
Interventions: CBTI-PE, Hygiene-PE; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 19 Years and older
Enrollment: 94 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: San Diego, California

Conditions: Restless Legs Syndrome (RLS)
Interventions: L-Tyrosine; Dietary Supplement
Lead sponsor: Seton Healthcare Family; Other
Eligibility: 18 Years to 80 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Austin, Texas

Conditions: TBI, Insomnia
Interventions: Sleep Education, Cognitive Behavior Therapy for Insomnia; Behavioral
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 49 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Autism Spectrum Disorder, Attention Deficit Hyperactivity Disorder, Sleep Disturbance
Interventions: Melatonin, Bedtime Bank; Dietary Supplement · Behavioral
Lead sponsor: University of Nebraska; Other
Eligibility: 10 Years to 18 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Omaha, Nebraska

Conditions: Bipolar Disorder, Sleep Problems, Suicidal Thoughts
Interventions: Brief Sleep Intervention; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: End-stage Renal Disease
Interventions: Cool Dialysate; Procedure
Lead sponsor: Emory University; Other
Eligibility: 21 Years to 75 Years
Enrollment: 58 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 2
States / cities: Atlanta, Georgia

Conditions: Sleep-Disordered Breathing
Interventions: Non-invasive technique to diagnose and quantitate sleep-disordered breathing; Procedure
Lead sponsor: National Center for Research Resources (NCRR); NIH
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
U.S. locations: 1
States / cities: New York, New York

Conditions: Chronic Low Back Pain (CLBP), Insomnia
Interventions: Cognitive-behavioral therapy for insomnia (CBTi), CBTi + Savoring Meditation, CBTi + Pain Education; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2030
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Sleep, Sleep Apnea
Interventions: Dreem; Diagnostic Test
Lead sponsor: Dreem; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 67 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018
U.S. locations: 1
States / cities: Redwood City, California

Conditions: Sleep Apnea
Interventions: computer model, Polysomnogram; Other
Lead sponsor: State University of New York at Buffalo; Other
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Buffalo, New York

Conditions: Obstructive Sleep Apnea
Interventions: Obstructive Sleep Apnea; Behavioral
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 18 Years and older
Enrollment: 217 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Creutzfeldt-Jakob Disease
Interventions: Quinacrine, Placebo; Drug
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2012
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Breast Cancer
Interventions: Relaxation Program, Questionnaires, Saliva Testing; Other · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older · Female only
Enrollment: 681 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2028
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Sleep Disturbances in Perimenopause
Interventions: Brahmi-Gotukola oil padabhyanga, Sesame oil Padabhyanga; Behavioral
Lead sponsor: Saipriya Gowrishankar; Other
Eligibility: 40 Years to 55 Years · Female only
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Fairfield, Iowa

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Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease

Bright Light Therapy for Residual Daytime Symptoms Associated With Obstructive Sleep Apnea

AVAPS-AE Efficacy Study

The Acute Effects of Onnit Alpha Brain on Cognition and Mood States

Physician Mental Health Study for Medical Trainees

Rainbow Acoustic Monitoring (RAM) Clinical Engineering Data Collection

An Evaluation of Insomnia Treatment to Reduce Cardiovascular Risk in Patients With Posttraumatic Stress Disorder

SM-1 vs 2 Comparators and Placebo in Participants With a History of Transient Insomnia.

Endotypic Traits and Obstructive Sleep Apnea Surgery

Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA)

Integrated CBT-I and PE on Sleep and PTSD Outcomes (Impact Study)

Efficacy of Tyrosine in Restless Legs Syndrome

Cognitive Behavior Therapy for Insomnia (CBT-I) in Persons With Traumatic Brain Injury (TBI)

A SMART Design to Improve Sleep Disturbance in Adolescents With Neurodevelopmental Disorders

Brief Sleep Intervention for Bipolar Disorder

The Effects of Cool Dialysate on the Sleep/Wake Cycle in Patients on Chronic Hemodialysis - "The Sleep Cool Study"

Incorporating Flow Limitation Into the Diagnosis and Quantification of Sleep Disordered Breathing

Resilience Enhancement Following Sleep Treatment

Comparison of Dreem to Clinical PSG for Sleep Monitoring in Apnea Patients

Artificial Neural Network Directed Therapy of Severe Obstructive Sleep Apnea

Patient Perception Questionnaire Validation

CJD (Creutzfeldt-Jakob Disease) Quinacrine Study

Relaxation for Women With Breast Cancer Undergoing Radiotherapy

A Study Comparing the Effects of Two Types of Natural Oils Used in a Bedtime Foot Massage Routine on Sleep and Emotional Well-Being in Perimenopausal Women.