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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:22 AM EST

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Showing 505–528 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Pulmonary Arterial Hypertension, Obstructive Sleep Apnea
Interventions: Not listed
Lead sponsor: Inova Health Care Services; Other
Eligibility: 18 Years and older
Enrollment: 2 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Falls Church, Virginia

Conditions: Diabetes Mellitus, Hypertension, Metabolic Disease, Obesity, Sleep Apnea Syndrome
Interventions: Orlistat, Placebo; Drug
Lead sponsor: Jack Yanovski; NIH
Eligibility: 12 Years to 17 Years
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 1998 – 2011
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Idiopathic Hypersomnia, Narcolepsy Without Cataplexy
Interventions: BTD-001, Placebo; Drug
Lead sponsor: Balance Therapeutics; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 23
States / cities: Birmingham, Alabama • Palo Alto, California • San Diego, California + 19 more

Conditions: Sleep Apnea, Hypertension, Hyperlipidemia, Coronary Artery Disease, Gastroesophageal Reflux Disease, Osteoarthritis, Diabetes
Interventions: Tri Staple Technology stapler; Device
Lead sponsor: Medtronic - MITG; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Sleep Apnea, Pediatric Sleep Apnea
Interventions: 3D printed NIV mask; Device
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 5 Years to 25 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Cardiovascular Disease, Obstructive Sleep Apnea, Coronary Artery Disease
Interventions: Healthy Lifestyles and Sleep Education plus PAP, Healthy Lifestyles and Sleep Education plus Supplemental Oxygen, Healthy Lifestyles and Sleep Education; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 45 Years to 75 Years
Enrollment: 318 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 4
States / cities: Baltimore, Maryland • Boston, Massachusetts • Cleveland, Ohio

Conditions: Obstructive Sleep Apnea
Interventions: Surgical OSA treatment, Positive Airway Pressure Therapy; Procedure
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depression, Anxiety, Insomnia, Substance Abuse
Interventions: TES Treatment, TES-SHAM Treatment; Device
Lead sponsor: University of Arizona; Other
Eligibility: 18 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Belle Mead, New Jersey

Conditions: Leg Cramps, Nocturnal
Interventions: vitamin d, placebo; Drug
Lead sponsor: University of Wisconsin, Madison; Other
Eligibility: 50 Years and older
Enrollment: 29 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Madison, Wisconsin

Conditions: Obstructive Sleep Apnea
Interventions: N-acetylcysteine (NAC), Placebo, Positive Airway Pressure (PAP) Therapy; Dietary Supplement · Procedure
Lead sponsor: NYU Langone Health; Other
Eligibility: 55 Years to 75 Years
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: New York, New York

Conditions: Obstructive Sleep Apnea (OSA)
Interventions: Combination product of Atomoxetine and Oxybutynin, Placebo, 2 tablets; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 65 Years
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia, Primary, Depression
Interventions: dCBTI, Sleep Education; Behavioral
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Enrollment: 1,385 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2018
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Sleep Disturbance
Interventions: melatonin; Dietary Supplement
Lead sponsor: Rothman Institute Orthopaedics; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Egg Harbor, New Jersey

Conditions: Posttraumatic Stress Disorder, Insomnia Disorder
Interventions: Brief Behavioral Treatment for Insomnia (BBTI), Progressive Muscle Relaxation Training (PMRT); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years to 75 Years
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Posttraumatic Stress Disorder, Insomnia, Cardiovascular Diseases, Metabolic Disease
Interventions: Behavioral Sleep Education Intervention; Behavioral
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 50 Years and older
Enrollment: 167 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: North Hills, California

Conditions: Bipolar Disorder, Sleep Problems, Suicidal Thoughts
Interventions: Brief Sleep Intervention; Behavioral
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Fatigue
Interventions: Mandatory Naps; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 352 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Stress Disorders, Post-Traumatic, Sleep Initiation and Maintenance Disorders
Interventions: True group auricular acupuncture, Sham group auricular acupuncture, Wait-List Control Group; Other
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 35 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Washington D.C., District of Columbia

Conditions: Primary Insomnia
Interventions: eszopiclone, placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 25 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Apnea
Interventions: Sleep apnea symptom survey; Other
Lead sponsor: Vidya Raman; Other
Eligibility: 3 Years to 18 Years
Enrollment: 948 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Age-related Macular Degeneration, Age-related Maculopathy
Interventions: Observational-1, Observational-2; Other
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 49 Years and older
Enrollment: 603 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2027
U.S. locations: 2
States / cities: Los Angeles, California • Pittsburgh, Pennsylvania

Conditions: Sleep Disordered Breathing, Able Bodied
Interventions: Acetazolamide + supplemental oxygen + PAP therapy, Zolpidem + PAP therapy, Buspirone + PAP therapy; Drug
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 200 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2027
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Insomnia, Primary Insomnia, Secondary Insomnia
Interventions: Cognitive-Behavioral Therapy; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2006
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Transient Insomnia
Interventions: Ramelteon, Placebo; Drug
Lead sponsor: Takeda; Industry
Eligibility: 18 Years to 64 Years
Enrollment: 289 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2003
U.S. locations: 12
States / cities: Palm Springs, California • San Diego, California • Miami, Florida + 9 more

Search by objective public record fields.

Obstructive Sleep Apnea (OSA) in Pulmonary Arterial Hypertension (PAH)

Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases

A Study of Safety and Efficacy of BTD-001 in Treatment of Patients With Idiopathic Hypersomnia (IH) or Narcolepsy Type 2

Tri Staple Technology Stapler Used in Gastric Bypass

Use of a 3D Printer to Make Custom Sleep Masks for Positive Airway Pressure Treatment

Heart Biomarker Evaluation in Apnea Treatment

Measuring Effectiveness in Sleep Apnea Surgery

Nexalin Therapy as a Viable Adjunctive Treatment for Substance Use Disorders

Vitamin D for Painful Nocturnal Leg Cramps

Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC)

Atomoxetine and Oxybutynin in Obstructive Sleep Apnea

Sleep to Prevent Evolving Affecting Disorders

Sleep Quality and Pain Medication Use Following Arthroscopic Rotator Cuff Repair

Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

Brief Sleep Intervention for Bipolar Disorder

A Randomized Controlled Trial of Mandatory Naps for Physicians in Training

Examining the Effect of Acupuncture on Sleep Difficulties Related to Post Traumatic Stress Disorder

Sleep Loss and Mechanisms of Impaired Glucose Metabolism

Revisiting Parental Survey for Screening for Obstructive Sleep Apnea in Patients Undergoing Polysomnography

GARM II: A Study on the Genetics of Age-related Maculopathy

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

Behavioral Insomnia Therapy in Primary Care

Efficacy of Ramelteon on Transient Insomnia in Healthy Adults