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ClinicalTrials.gov public records Last synced Nov 15, 2026, 3:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 529–552 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Poor Quality Sleep
Interventions: Well-Being Intervention, Sleep Hygiene; Behavioral
Lead sponsor: Columbia University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 76 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: New York, New York

Conditions: Nightmare, Insomnia, PTSD, TBI, Sleep Disorder (Disorder), REM Behavior Disorder
Interventions: NightWare smartwatch configured to detect physiological signs of sympathetic activation during sleep, such as heart-rate spikes and movement patterns., Sham (No Treatment); Device
Lead sponsor: Uniformed Services University of the Health Sciences; Federal
Eligibility: 18 Years to 62 Years
Enrollment: 180 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 2
States / cities: Bethesda, Maryland • Minneapolis, Minnesota

Conditions: Dysbiosis
Interventions: Creamy Richards 100% Peanuts! Creamy Natural Peanut Butter, Cadbury Milk Chocolate Spread; Other
Lead sponsor: Florida State University; Other
Eligibility: 6 Years to 13 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Tallahassee, Florida

Conditions: Acid Reflux Disease, Obstructive Sleep Apnea
Interventions: Pantoprazole; Drug
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 68 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2004 – 2006
U.S. locations: 1
States / cities: Cincinnati, Ohio

Conditions: Type 2 Diabetes Mellitus, Insomnia, Sleep Disorder, Inflammation
Interventions: Suvorexant, Placebo; Drug · Other
Lead sponsor: Massachusetts General Hospital; Other
Eligibility: 25 Years to 75 Years
Enrollment: 108 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Apnea
Interventions: Induced central apneas; Other
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2017
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstructive Sleep Apnea
Interventions: Pillar Palatal Implants; Device
Lead sponsor: University of Cincinnati; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2006
U.S. locations: 3
States / cities: Indianapolis, Indiana • Cincinnati, Ohio • Milwaukee, Wisconsin

Conditions: Healthy, Narcolepsy
Interventions: MK-6552, MK-6552 placebo, Modafinil, Modafinil placebo; Drug
Lead sponsor: Merck Sharp & Dohme LLC; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024
U.S. locations: 2
States / cities: Atlanta, Georgia • Eatontown, New Jersey

Conditions: Sleep Initiation and Maintenance Disorders
Interventions: SHIP (Sleep Health in Preschoolers), SHIP Control Arm; Behavioral
Lead sponsor: Seattle Children's Hospital; Other
Eligibility: 30 Months to 71 Months
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2020
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Obstructive Sleep Apnea, Bariatric Surgery
Interventions: Not listed
Lead sponsor: Summa Health System; Other
Eligibility: 20 Years to 85 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2010
U.S. locations: 1
States / cities: Akron, Ohio

Conditions: Respiratory Complication, Obstructive Sleep Apnea
Interventions: Sugammadex 100 MG/ML [Bridion]; Drug
Lead sponsor: University of California, Los Angeles; Other
Eligibility: 18 Years and older
Enrollment: 12,248 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: PTSD, Sleep, Obstructive Sleep Apnea, Quality of Life
Interventions: Not listed
Lead sponsor: Veterans Medical Research Foundation; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 1
States / cities: San Diego, California

Conditions: Dementia, Alzheimer Disease, Circadian Rhythm Disorders, Circadian Rhythm Sleep Disorder, Insomnia, Hypersomnia, Cognitive Impairment, Cognitive Decline, Mild Cognitive Impairment, Frontotemporal Dementia, Neurocognitive Disorders, Vascular Dementia, Sleep Disorder, Memory Impairment
Interventions: Attention-Control Condition, Timed Activity Intervention; Behavioral
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 110 Years
Enrollment: 421 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2021
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obstructive Sleep Apnea
Interventions: CPAP withdrawal; Other
Lead sponsor: Johns Hopkins University; Other
Eligibility: 20 Years to 75 Years
Enrollment: 144 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2022
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Obstructive Sleep Apnea
Interventions: F&P Toffee; Device
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 22 Years and older
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Sleep Quality, Sleep Health
Interventions: Sleep Supplement, Placebo; Dietary Supplement
Lead sponsor: 4Life Research, LLC; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 30 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Sandy City, Utah

Conditions: Obesity, Obstructive Sleep Apnea Syndrome
Interventions: Not listed
Lead sponsor: University of Rochester; Other
Eligibility: 8 Years to 18 Years
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2004
U.S. locations: 1
States / cities: Rochester, New York

Conditions: Insufficient Sleep, Physical Inactivity, Sedentary Behavior, Obesity
Interventions: Sleep intervention, Contact Control; Behavioral
Lead sponsor: University of Minnesota; Other
Eligibility: 21 Years to 65 Years
Enrollment: 80 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2026
U.S. locations: 1
States / cities: Minneapolis, Minnesota

Conditions: Obstructive Sleep Apnea
Interventions: Ultrasound Exam, Polysomnography; Device
Lead sponsor: Henry Ford Health System; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Detroit, Michigan

Conditions: Obstructive Sleep Apnea
Interventions: Tonsillectomy; Procedure
Lead sponsor: University of Southern California; Other
Eligibility: 17 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2015
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
Interventions: Simulated short term night shift work schedule; Behavioral
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 20 Years to 40 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2025
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Insomnia
Interventions: ACT Guide for Insomnia; Behavioral
Lead sponsor: Utah State University; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2025
U.S. locations: 1
States / cities: Logan, Utah

Conditions: Post-Traumatic Stress Disorder, Sleep Initiation and Maintenance Disorders
Interventions: Prazosin, Placebo, Psychotherapy; Drug · Behavioral
Lead sponsor: Seattle Institute for Biomedical and Clinical Research; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2010
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Obstructive Apnea
Interventions: Portable oxygen concentrator Inogen G5 model; Device
Lead sponsor: Children's Hospital Medical Center, Cincinnati; Other
Eligibility: 5 Years to 17 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2028
U.S. locations: 1
States / cities: Cincinnati, Ohio

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Well-being Promotion and Sleep Hygiene Education to Improve Sleep Quality

INSIGHT: Insomnia, Nightmares, and Sympathetic Hyperactivity Intervention

Effect of Peanut Butter on Gut and Metabolic Health

Study of Pantoprazole for Sleepiness Associated With Acid Reflux and Sleep Apnea

Suvorexant on Sleep Disturbance in Patients With Chronic Insomnia and Suboptimally Controlled Type 2 Diabetes

Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study D

Study to Determine the Effectiveness of Pillar Palatal Implants to Treat Obstructive Sleep Apnea

A Study of MK-6552 in Sleep Deprived Healthy Participants (MK-6552-003)

Sleep Health in Preschoolers: a Randomized Controlled Trial

Bariatric Surgery and Obstructive Sleep Apnea

Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications

Effects of CPAP Therapy on PTSD Symptoms

The Healthy Patterns Sleep Study

Metabolic Impact of Intermittent CPAP

Evaluation of the F&P Toffee Nasal Pillows Mask, US, 2022

Clinical Study to Assess a Dietary Supplement on Sleep Health and Quality

Pilot Study to Assess the Effectiveness of Tonsil and Adenoidectomy (T+A) in Overweight Children and Adolescents

Social Determinants of Sleep and Obesity

Ultrasound Against Obstructive Sleep Apnea

Tonsillectomy in Adults With Tonsillar Hypertrophy and Obstructive Sleep Apnea

Skeletal Response to Simulated Night Shift

An ACT Website for College Students With Insomnia

Prazosin for Treating Noncombat Trauma Post-Traumatic Stress Disorder

Comparison of a Demand Oxygen Delivery