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ClinicalTrials.gov public records Last synced Nov 15, 2026, 4:31 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 601–624 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Insomnia
Interventions: Quetiapine, Cogntive behavioral therapy; Drug · Behavioral
Lead sponsor: Michael E. DeBakey VA Medical Center; Federal
Eligibility: 60 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Insomnia, Coronary Heart Disease
Interventions: Go! to Sleep, General Sleep Education; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years and older
Enrollment: 34 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Sleep Deprivation
Interventions: sleep deprivation, Normal sleep; Other
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Shift-Work Sleep Disorder, Shift Work Type Circadian Rhythm Sleep Disorder, Sleep Disorders, Circadian Rhythm, Sleep Disorders, Intrinsic, Advanced Sleep Phase Syndrome (ASPS), Advanced Sleep Phase Syndrome, Advanced Sleep Phase, Delayed Sleep Phase, Delayed Sleep Phase Syndrome, Non-24 Hour Sleep-Wake Disorder, Irregular Sleep-Wake Syndrome
Interventions: Short Nap Intervention, No Nap Intervention; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 18 Years to 50 Years
Enrollment: 5 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2025
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acute Decompensated Heart Failure, Sleep Disordered Breathing
Interventions: MV ASV, Optimized Medical Treatment; Device · Drug
Lead sponsor: ResMed; Industry
Eligibility: 21 Years and older
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2015
U.S. locations: 14
States / cities: Huntsville, Alabama • Los Angeles, California • Denver, Colorado + 11 more

Conditions: Insomnia
Interventions: Cold Pressor Test; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 55 Years
Enrollment: 44 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Preeclampsia, Hypertension
Interventions: Positive Airway Pressure; Device
Lead sponsor: University of Michigan; Other
Eligibility: 14 Years and older · Female only
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Obesity, Rhinitis, Rhinitis, Allergic, Respiratory Sounds, Dyspnea, Headache, Migraine Disorders, Arthritis, Arthralgia, Anxiety, Sleep Initiation and Maintenance Disorders, Sleep Deprivation
Interventions: Vitamin A, Vitamin B6, Vitamin C, Nicotinamide, Vitamin D3, Vitamin E, Broccoli, Spinach, Caffeine, Coffee, Axon Eyewear, Chocolate; Dietary Supplement · Other · Device
Lead sponsor: Verifomics LLC; Industry
Eligibility: 18 Years and older
Enrollment: 16 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Obstructive Sleep Apnea
Interventions: Placebo oral tablet, Trazodone Hydrochloride; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 70 Years
Enrollment: 18 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2026
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Taking Benzodiazepines for Any Reason for 3 Months, Benzodiazepine Dependence
Interventions: EMPOWER-ED; Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: Not listed
Enrollment: 170 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Sleep, Sleep Disturbance, Sleep Disorder
Interventions: Rest Study Active Product 1.1 Usage, Rest Study Active Product 1.2 Usage, Rest Study Active Product 2.1 Usage, Rest Study Active Product 2.2 Usage, Placebo Control Form 1, Placebo Control Form 2, Placebo Control Form 3, Rest Study Active Product 3.1 Usage, Placebo Control Form 4, Rest Study Active Product 4.1 Usage, Rest Study Active Product 4.2 Usage, Rest Study Active Product 4.3 Usage; Dietary Supplement
Lead sponsor: Radicle Science; Industry
Eligibility: 21 Years to 105 Years
Enrollment: 4,152 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Del Mar, California

Conditions: Sleep Quality, Sleep Duration, Fatigue, Energy Levels, Overall Health and Well-Being
Interventions: Sleep Well Diffuser Blend followed by Sleep Well Roll-On; Dietary Supplement
Lead sponsor: Saie Beauty; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026
U.S. locations: 1
States / cities: Las Vegas, Nevada

Conditions: Anxiety
Interventions: Anxiety Management Education, 10 week tai chi intervention, Enhanced tai chi instruction; Behavioral
Lead sponsor: Appalachian State University; Other
Eligibility: 18 Years to 40 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2014
U.S. locations: 1
States / cities: Boone, North Carolina

Conditions: Obstructive Sleep Apnea
Interventions: Auto-titrating mandibular positioner test; Device
Lead sponsor: Zephyr Sleep Technologies; Industry
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 1
States / cities: Encino, California

Conditions: Obstructive Sleep Apnea
Interventions: Ketorolac, Standard of Care; Drug
Lead sponsor: Emory University; Other
Eligibility: 2 Years to 18 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Insomnia
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I); Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 21 Years to 70 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Sleep Initiation and Maintenance Disorders
Interventions: Cognitive behavioral treatment (CBT) delivered over the Internet; Behavioral
Lead sponsor: University of Virginia; Other
Eligibility: 18 Years to 65 Years
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2009
U.S. locations: 1
States / cities: Charlottesville, Virginia

Conditions: Insomnia, Related Distress Among Cancer Caregivers
Interventions: Cognitive Behavioral Therapy for Insomnia (CBT-I), Acupuncture, questionnaires, Diurnal Cortisol; Behavioral · Procedure · Other
Lead sponsor: Memorial Sloan Kettering Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 13 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2020
U.S. locations: 3
States / cities: Irvine, California • New York, New York

Conditions: Primary Insomnia
Interventions: Acupuncture; Other
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 60 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Fatigue, Head and Neck Cancer, Psychosocial Effects of Cancer and Its Treatment, Sleep Disorders
Interventions: medical chart review, questionnaire administration, fatigue assessment and management, quality-of-life assessment; Other · Procedure
Lead sponsor: Vanderbilt University; Other
Eligibility: 21 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2007
U.S. locations: 3
States / cities: Nashville, Tennessee

Conditions: Critical Illness, Sleep Deprivation, Respiratory Failure, Sleep Disorders, Circadian Rhythm
Interventions: Sleep and circadian rhythm promotion, Usual care; Behavioral
Lead sponsor: Brian Gehlbach; Other
Eligibility: 18 Years and older
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 2
States / cities: Chicago, Illinois • Iowa City, Iowa

Conditions: Schizophrenia and Related Disorders, Sleep Disturbance
Interventions: SPARK Healthy Sleep; Device
Lead sponsor: Indiana University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 115 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Indianapolis, Indiana

Conditions: Heart Failure, Sleep Apnea Syndromes
Interventions: Continuous positive airway pressure, Nocturnal supplemental oxygen, Healthy Lifestyle and Sleep Education; Device · Behavioral
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 74 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2020
U.S. locations: 2
States / cities: West Haven, Connecticut • Boston, Massachusetts

Conditions: Snoring, Mouth Breathing, Obstructive Sleep Apnea
Interventions: myTAP oral appliance plus mouth shield, myTAP oral appliance alone for first 4 weeks; Device
Lead sponsor: Texas A&M University; Other
Eligibility: 18 Years and older
Enrollment: 89 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Dallas, Texas

Search by objective public record fields.

Group Cognitive Behavioral Therapy (CBT I) Vs. Quetiapine for Residual Insomnia Impairing Recovery Among Elderly With Stable Major Affective Disorders

Improving Sleep for Healthy Hearts

Sleep Deprivation and Energy Balance

Breath Biomarkers for Sleep Loss and Circadian Timing

Cardiovascular Improvements With MV ASV Therapy in Heart Failure

Challenging the Inflammatory Response System in Insomnia Disorder

Study of Positive Airway Pressure in Preeclampsia to Reduce Blood Pressure

Interventional Testing of Gene-environment Interactions Via the Verifomics Mobile Application

Trazodone on OSA Endotypes

Promoting Benzodiazepine Cessation Through an Electronically-delivered Patient Self-management Intervention

Radicle Rest 2: A Study of Health and Wellness Products on Sleep and Health Outcomes

A Clinical Trial to Evaluate the Effects of a Topical Roll-on and Diffuser Blend on Sleep Quality and Sleep Duration

Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults

A Study for Obstructive Sleep Apnea Using a New At-Home Sleep Test

Effect of Ketorolac on Post Adenotonsillectomy Pain

The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & Relapse

Effectiveness of Internet Cognitive Behavioral Therapy Intervention for Treating Insomnia

Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers

Acupuncture for the Treatment of Insomnia

Insomnia in Patients Undergoing Chemotherapy and Radiation Therapy for Head and Neck Cancer

Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients

SPARK Healthy Sleep

Oxygen Versus PAP for Sleep Apnea in Heart Failure

OA Therapy for Mouth-breathers Who Snore