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ClinicalTrials.gov public records Last synced Nov 15, 2026, 6:52 AM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 841–864 of 2,615 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Sleep-Wake Disorders Clear all

Conditions: Obstructive Sleep Apnea, Stroke
Interventions: continuous positive airway pressure or CPAP, sham CPAP; Device
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2010
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Opioid Dependence, Opioid Withdrawal, Sleep Disturbance
Interventions: Placebo oral capsule, Low Dose Suvorexant, High Dose Suvorexant; Drug
Lead sponsor: Johns Hopkins University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Shift-Work Sleep Disorder
Interventions: eszopiclone, matching placebo; Drug
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 20 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia, Depression
Interventions: Cognitive Behavioral Therapy for Insomnia; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Palo Alto, California

Conditions: Obstructive Sleep Apnea, Hypoxia, Insulin Resistance
Interventions: Continuous Positive Airway Pressure; Device
Lead sponsor: University of California, San Francisco; Other
Eligibility: 19 Years to 100 Years
Enrollment: 48 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Bruxism, Sleep-Related
Interventions: Not listed
Lead sponsor: Otis Dental, LLC; Industry
Eligibility: 18 Years to 50 Years · Male only
Enrollment: 2 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Sleep Deprivation
Interventions: SPD489 20 mg, SPD489 50 mg, SPD489 70 mg, Armodafinil, Placebo; Drug
Lead sponsor: Shire; Industry
Eligibility: 18 Years to 40 Years · Male only
Enrollment: 135 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: New York, New York

Conditions: Obstructive Sleep Apnea Syndrome
Interventions: OxiplexTS; Device
Lead sponsor: ISS, Inc.; Industry
Eligibility: 21 Years to 55 Years
Enrollment: 309 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2010
U.S. locations: 4
States / cities: Orange, California • Stanford, California • Chicago, Illinois + 1 more

Conditions: Post Traumatic Stress Disorder, Traumatic Brain Injury
Interventions: Transcutaneous nerve stimulation location 1; Device
Lead sponsor: University of Florida; Other
Eligibility: 18 Years to 55 Years
Enrollment: 221 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017 – 2025
U.S. locations: 3
States / cities: Gainesville, Florida • Jacksonville, Florida

Conditions: Lung Cancer
Interventions: Armodafinil, Placebo, Minocycline, Questionnaires; Drug · Other · Behavioral
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Chronic Pain, Musculoskeletal Pain, Sleep Disturbance, Pain Disorders
Interventions: Weighted Blanket; Device
Lead sponsor: National University of Natural Medicine; Other
Eligibility: 18 Years and older
Enrollment: 44 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Sleep Apnea, Obstructive
Interventions: Oral appliance, BluePro oral appliance; Device
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 70 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Insomnia
Interventions: Sleep Wellness Device (BeCurie); Device
Lead sponsor: University of Utah; Other
Eligibility: 18 Years and older
Enrollment: 59 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Salt Lake City, Utah

Conditions: Insomnia
Interventions: zolpidem tartrate; Drug
Lead sponsor: Sanofi; Industry
Eligibility: 18 Years to 45 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006
U.S. locations: 1
States / cities: Bridgewater, New Jersey

Conditions: Sleep Apnea, Obstructive
Interventions: CPAP with ThermoSmart, then CPAP without ThermoSmart, CPAP without ThermoSmart, then CPAP with ThermoSmart; Device
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Obstructive Sleep Apnea
Interventions: SensAwake On, SensAwake Off; Device
Lead sponsor: Fisher and Paykel Healthcare; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 70 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 3
States / cities: Glendale, Arizona • Macon, Georgia • Columbia, South Carolina

Conditions: Obstructive Sleep Apnea
Interventions: Autoadjusting CPAP (VPAP Auto), CPAP; Device
Lead sponsor: MetroHealth Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Parkinson Disease
Interventions: e-Tapper TT-R1; Device
Lead sponsor: Boston University; Other
Eligibility: 50 Years to 75 Years
Enrollment: 21 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Obstructive Sleep Apnea
Interventions: SleepFlex; Device
Lead sponsor: Berendo Scientific, LLC; Industry
Eligibility: 21 Years and older
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Narcolepsy, Idiopathic Hypersomnia
Interventions: Xywav, Placebo; Drug · Other
Lead sponsor: Jazz Pharmaceuticals; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2028
U.S. locations: 15
States / cities: Birmingham, Alabama • Irvine, California • Long Beach, California + 12 more

Conditions: Sleep Initiation and Maintenance Disorders, Obesity
Interventions: Diet and exercise, Cognitive Behavioral Therapy, Passion and Balance; Behavioral
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 28 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2010
U.S. locations: 1
States / cities: Stanford, California

Conditions: Rett Syndrome, Prader-Willi Syndrome, Angelman Syndrome, Sleep Problems
Interventions: Not listed
Lead sponsor: Baylor College of Medicine; Other
Eligibility: 1 Year to 18 Years
Enrollment: 804 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2013
U.S. locations: 9
States / cities: Birmingham, Alabama • Irvine, California • San Diego, California + 6 more

Conditions: Dementia, Parkinsonism, Mild Cognitive Impairment, REM Sleep Behavior Disorder
Interventions: I-123 Ioflupane solution injection prior to SPECT scan (DaTscan), Single photon emission computed tomography (SPECT) scan; Drug · Device
Lead sponsor: Mayo Clinic; Other
Eligibility: 40 Years to 90 Years
Enrollment: 500 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2026
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Moderate to Severe Insomnia
Interventions: Transcranial alternating current stimulator; Device
Lead sponsor: Nexalin Technology; Industry
Eligibility: 22 Years to 65 Years
Enrollment: 160 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027
U.S. locations: 1
States / cities: Houston, Texas

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Sleep Apnea Treatment After Stroke (SATS)

Medical Management of Sleep Disturbance During Opioid Tapering

Effects of Daytime Eszopiclone Administration in Shift Workers

Sleep Mechanisms Of Regulating Emotions

Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia

A Sensor-enhanced Mouth Guard to Quantitatively Measure Bite Compression Forces.

Pharmacodynamic Profile of SPD489 in Healthy Adult Males Undergoing a Nocturnal Period of Acute Sleep Loss

Brain Oxygenation and Hemodynamics During Sleep in Obstructive Sleep Apnea Sufferers

Non-invasive Nerve Stimulation for PTSD and Sleep

A Study for Reducing Symptom Burden Produced by Chemoradiation Treatment for Non Small Cell Lung Cancer by Minocycline and Armodafinil

Weighted Blanket Use for Adults With Chronic Pain

Characterizing Upper Airway Collapse to Guide Patient Selection for Oral Appliance Therapy for Obstructive Sleep Apnea

A Novel Wearable Device to Improve Sleep Quality

Residual Effects of Zolpidem Tartrate Extended Release and Eszopiclone Vs Placebo

ThermoSmart® Versus Conventional Humidification in Continuous Positive Airway Pressure (CPAP)

Comparison Study of the ICON™ CPAP Series With and Without SensAwake™

CPAP vs AutoCPAP for Treatment of Obstructive Sleep Apnea (OSA) in the Postoperative Setting

Bio Electro Stimulation Therapy for Parkinson's Disease

SleepFlexTM Treatment of Obstructive Sleep Apnea

A Study Evaluating the Efficacy and Safety of Xywav Expanded Dosing vs Placebo in Participants With Narcolepsy or IH

Adding Sleep Intervention to Traditional Diet and Exercise Approach to Weight Loss

Sleep Abnormalities in Rare Genetic Disorders: AS, RTT, and PW

DaTSCAN Imaging in Aging and Neurodegenerative Disease

HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia